I have had those kind of days too. Cecelia is right on. I think heat helps to "seal the deal". I even use a hairdryer sometimes to heat up the area. I also try not to lay down right after changing so the stuff doesn't back up around the wafer until it seals. Hope you find the answer.
Where r u storing your supplies? I've been wondering if this makes a difference. Like if we store them where it is too hot, or too cold does it contribute tho their effectiveness? Do u have a nurse u can call to get some assistance? I can't imagine how ur skin must b doing with the constant putting on and takingo off. I hope u find relief soon