Is the Zoladex working?

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Tony1951
Regular Member


Date Joined Jul 2008
Total Posts : 49
   Posted 8/30/2008 11:12 PM (GMT -6)   
 
I had my first shot of Zoladex on 8/26/2008.  I was told that my libido would go away, that I would have hot flashes and that I may feel moody.  I know it's only been like five days, but while I'm happy that I seem to be tolerating the drug, I am concerned that since I don't feel anything different, perhaps it isn't doing its job.
I still get aroused looking at my wife, and I haven't experienced so much as a mild flush.  Any feedback on this would be most appreciated.  I would especially like to hear from someone who has taken zoladex shots.
 
Thanks,

aus
Regular Member


Date Joined Sep 2006
Total Posts : 211
   Posted 8/31/2008 4:27 AM (GMT -6)   
 
Not everyone experiences  the acute side effects often mentioned. It is too early to judge how effective Zoladex will be for you: usually a PSA test is done at 3 months to gauge what's happening, when hopefully your PSA will be a very low figure.
 
If you havn't already done so, I always suggest reading the book by Dr Myers mentioned in another recent post here, "Gleason 9 & Hormone Therapy". As discussed in that post I have two friends currently doing well on hormone therapy. In both instances their PSA reduced substantially to under 1 after 3 months. One uses Zoladex, and his PSA reduced from 50 to .2 at 3 months then .04 at 9 months.
 
Best wishes,
 
John

Tony1951
Regular Member


Date Joined Jul 2008
Total Posts : 49
   Posted 8/31/2008 7:53 AM (GMT -6)   

Thanks for the pompt reply John.  I don't think I'll have the benefit of knowing what effect the Zolladex is having on my PSA.  I'm suppose to be on it for a month or two (confused about the time frame at the moment) and then I start IMRT.  If I'm getting some benefit from the medication without the side effects I've heard about, I woud be very pleased.  There are no noticable  physiological or psychological effects form the shot.

Steve


hopemylove
Regular Member


Date Joined Apr 2008
Total Posts : 65
   Posted 8/31/2008 8:15 AM (GMT -6)   

Morning,

Five days is a little soon to experience any of the side effects of HT--this does not mean the PSA isn't dropping though. Think positive. Enjoy your libido while you have it!!

Karen eyes


Karen--New York
Husbands Info:
Age of diagnosis--62
2/28/08--PSA 279   DRE--positive/rock hard
Flomax and Casadex started
Biopsy--3/7/08--187cc--Gleason 10--12 of 12 positive--Perineural and LV invasion identified
T4 bone met.--hydroureteronephrosis/right kidney
3/28/08--Lupron Inj. started
4/7/08--Zometa IV started
5/15/08--PSA 12
5/20/08--Tubes placed in kidneys (through back)
5/21/08--diagnosed Neuro Endocrine Prostate carcinoma
5/28-30/08--1st round Chemo
6/18-20/08--2nd round Chemo
7/2/08--blood clot--Coumadin started
7/10/08--Stop chemo--cancer not responding
7/20-24--hospitalized for some type of seizure
7/24--New chemo given-no response
8/20/08--Start Hospice
 
 
 


Tony1951
Regular Member


Date Joined Jul 2008
Total Posts : 49
   Posted 8/31/2008 9:08 PM (GMT -6)   
hopemylove said...

Morning,

Five days is a little soon to experience any of the side effects of HT--this does not mean the PSA isn't dropping though. Think positive. Enjoy your libido while you have it!!

Karen eyes

 And here I was thinking I was going to dodge the hot flashes....

sterd82
Regular Member


Date Joined Sep 2006
Total Posts : 187
   Posted 9/2/2008 7:34 AM (GMT -6)   
It took me a good month before I had hot flashes/libido loss.   Libido actually went UP right after the shot (testosteronoe burn off).   GOOD LUCK!
Sterd82
Age 47 - pre-surgery PSA 39
Open Radical Prostatectomy 6/9/2006
Pathological Stage T3a, Positive Surgical Margin
Gleason 3+4
PSA rose to .24 in November of 2006
6 month hormone therapy initiated December 1. 2006
36 sessions of IMRT Ended Feb 1, 2007
PSA as of May 25, 2007 undetectable
PSA as of November 29, 2007 undetectable
PSA as of May 14, 2008 undetectable
Next PSA November of 2008

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