I am using bi-mix too. My experience is that I need about .4 to .5 ml to be effective. I too have noticed a curve at times. It appears to curve more when it is hardest.
I too wondered about adding the third ingredient, but I have already tried and rejected the 100% alprostadil (Caverject) due to etreme discomfort. However, if I am given some assurance that the smaller amount in tri-mix works with out the pain, I will give that a try.
I hope that we both can get some other persons's opinion and experience.
I now have a penile implant but when I was using injections I also found that I needed more and more of the Bimix to get a firm enough erection and then I was having to put up with 3 to 4 hour long erections. I switched to Trimix but I had it formulated with one fourth the amount of Alprostadil then the normal formula. This combination dropped my dosage to 0.07 for Trimix from the 0.4 with Bimix. It gave me a firmer erection which lasted about half the time as the one with Bimix. I did have some aching with it but taking some Ibruprofen about 30 minutes before injecting helped a lot. I did have to get a prescription for the reformulated Trimix.
Thanks for your response. I would like to review the plump and prick technique. Where do you find the information? I have been stimulating the penis prior to injection and holding the base after while using the other hand to work the Trimix into both sides. The ring sounds like a great idea. Where do you purchase them?
I'm going to fill my Bimix Rx tomorrow and hope for good results without the after injection pain.
I switched from TriMix to BiMix due to the pain from PGE. I'm using .4ml per dose with decent results. The only difference is the erection with BiMix. It is adequate for intercourse, but isn't quite as good as it was with TriMix. The erection curves slightly downward toward the end although it is just as long. It isn't curving to the side so I don't believe that it is a side effect. Perhaps, not quite as much blood is entering the cavernosum without the PGE in the mix.
I'm thinking about trying TriMix again with only 1/4 of the usual PGE in the mix. Unfortunately, I'm one of the 33% that has a severe reaction to PGE so I'm reluctant to switch.
Has anyone out there had similiar experiences to mine?
My curvature is right at the end and it goes slightly down. I thought that Peyronie's only causes curvature to the side. This wasn't gradual but happened almost immediately after changing from TriMix to BiMix. I have an appt. with my Urol. in 2 weeks and I'll get his opinion. I do change injection sites from one side to the other everytime so I don't think that's the problem.