Surgery For The Under 50 yr Olds

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

NotHard
Veteran Member


Date Joined Mar 2009
Total Posts : 737
   Posted 5/19/2009 2:44 AM (GMT -6)   
A very positive report for those under 50 yrs of age, whom have chosen surgery.  Just thought I would
share it with you all..............Cheers Nothard
 
 
 
http://esciencenews.com/articles/2009/05/11/surgery.improves.survival.prostate.cancer.patients.younger.50
Age 51yrs
DX 11/11/08
6 out of 8 cores positive 3 X 60% / 3 X 10%
PSA 4
Gleason 3+4=7
Stage T1c
Robotic Surgery 24/12/08
Upgrade Gleason 4+3=7 (60% Grade 4)
Stage T2c
Three small foci total volume 10%
Neg Margins and Nodes
Nil - Extraprostatic Extentions
Dry less than 1 week.
ED- taking Meds/ No results yet/still "NotHard"
PSA 28/1/09 0.03
PSA 24/2/09 0.03
"Everyday in Everyway I get better"


Squirm
Veteran Member


Date Joined Sep 2008
Total Posts : 692
   Posted 5/19/2009 10:24 AM (GMT -6)   
I saw that too. It was hard to believe that surgery offers that much of an advantage over other treatment options such as radition. I was taken back by this statement: (I'm not certain what the NDT group comprised of).

"The cancer-specific survival in the NDT group was 78 percent at 16 years, in the radiation group was 63 percent at 17 years; and 94 percent in the radical prostatectomy at 21 years. On a subset analysis the outcome was significantly better after radical prostatectomy in patients with moderately and poorly differentiated prostate cancer.

Overall, the study shows the 5-year, 10-year, 15-year and 20-year overall survival and cancer specific survival is significantly increased in patients who were less than 50 years of age with moderately and poorly differentiated cancers in the surgery group."

geezer99
Veteran Member


Date Joined Apr 2009
Total Posts : 990
   Posted 5/19/2009 3:48 PM (GMT -6)   
NDT = no definitive treatment = watchful waiting
Age at diagnosis 66, PSA 5.5
Biopsy 12/08 12 cores, 8 positive
Gleason 3 + 4 = 7
CAT scan 1/09 negative, Bone scan 1/09 negative

Robotic surgery 03/03/09 Catheter Removed 03/08/09
Post surgical pathology report. Lymph nodes negative, Seminal vesicles negative
Surgical margins positive, Capsular penetration extensive Gleason 4 + 3 = 7
At 6 weeks: 1 pad/day, 1 pad/night -- mostly dry at night.


Tudpock18
Forum Moderator


Date Joined Sep 2008
Total Posts : 2723
   Posted 5/19/2009 6:07 PM (GMT -6)   

Geezer...FYI, read a couple of posts on the thread on this same subject but quoted from Science Daily.  I think you'll see some good analysis of why the radiation numbers look bad in this report.

Tudpock


Age 62
Gleason 4 +3 = 7
T1C
PSA 4.2
2 of 16 cores cancerous
27cc
Brachytherapy December 9, 2008.  73 Iodine-125 seeds.  Procedure went great, catheter out before I went home, only minor discomfort.  Regular activities resumed, everything continues to function normally as of 5/1/09.

Kark60
Regular Member


Date Joined Jun 2008
Total Posts : 88
   Posted 5/19/2009 6:41 PM (GMT -6)   
What does "moderately and poorly differentiated cancer" mean. I assume this corresponds to a Gleason score... turn
Husband and father of two (current ages 5 and 7).
Age when diagnosed: 47 (currently 48)
Pre-surgery PSA: 13.7
Pre-surgery Gleason: 4+3=7
CT Scan, Bone Scan, PET Scan: Clear
Robotic Surgery on May 28, 2008, at Barnes Hospital in St. Louis.
Right nerve bundle spared; left bundle removed.
POST-SURGERY PATH REPORT:
Gleason: 4+3=7
Involved 10% of prostate; all quadrants involved
Extraprostatic extension at left base and apex
Extensive perineurual invasion present.
Bladder neck, lymphvasular space, seminal vesicles, 17 examined lymph nodes, and all surgical margins FREE of tumor.
T3a
Four-week post-surgical PSA = 0.1
Seven-week post-surgical PSA = .01
October 2008 PSA = 0.0
January 2009 PSA = 0.0
April 2009 PSA - 0.0
Next PSA scheduled for July 2009.


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 7701
   Posted 5/19/2009 8:39 PM (GMT -6)   
It doed Kark.
Gleason grade 2 to 4 is well differentiated.
Gleason grade 5 to 6 is moderate
Gleason grade 8 to 10 is poorly differentiated.

Gleason grade 7 can go either way from moderate to poor.

Tony
 Age 46 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Geason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 11, 2009): <0.1
 
My Journal is at Tony's Blog  
 
STAY POSITIVE!


Dirtmover
Regular Member


Date Joined Apr 2008
Total Posts : 158
   Posted 5/20/2009 3:16 PM (GMT -6)   
what an outstanding piece of info for some of those younger guyz who might be having a difficult time making their decision for treatmentfor some its an easy choice , for some its not , i so appriciate what this forum does for all whom need it  from recently dx to treated  i am gonna be a year out  in a few days going for the psa results friday ,, thank you my brothers  and sisters for all you have done ..................................dirt turn
Diagnosed November 2007   (43 years old )
PSA 3.9 / Gleason 6 / TC1 6 cores 1 shows 25%
Sugery scheduled 5/29/08 - City of Hope - Dr. Mark Kawachi
 "First show of the day"
 and now for the new ive been waiting for
 FINAL PATH REPORT:gleason upgraded to 3+4 T2c bilateral disease,tumor involvment 5%
extra prostatic extention:absent
seminal vesical invasion :absent
pathological staging:pTNM pT2 ORGAN CONFINED
margins free of carcinoma
usable erections ;6-6-08 with little blue pill
continence; 1 pad a day, dry at night
continence a non issue at 10weeks


Squirm
Veteran Member


Date Joined Sep 2008
Total Posts : 692
   Posted 5/20/2009 3:23 PM (GMT -6)   
Dirt,
But I wonder how well this was researched. To me it seems if surgery had this much of an advantage over radiation in younger men, it would have been recognized long ago.

Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 7701
   Posted 5/20/2009 3:38 PM (GMT -6)   
Squirm,
It was. This study is based upon the last 16 to 20 years. Certainly something that should matter to the youngest here...Before that, the use of EBRT technology, the only available technology twenty years ago, was highly destructive. It was seldom considered as a primary treatment for prostate cancer, though it was used for salvage therapy regularly. We have seen a huge improvement in delivering radiation through IMRT, Proton, IGRT and seeding. Less initial side effects....

Tony
 Age 46 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Geason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 11, 2009): <0.1
 
My Journal is at Tony's Blog  
 
STAY POSITIVE!


Paul1959
Veteran Member


Date Joined Nov 2007
Total Posts : 597
   Posted 5/20/2009 4:15 PM (GMT -6)   
This study confirms everything I was told by two urologists and all four surgeons I saw. Without hesitation, they looked at my numbers and said surgery was basically my only option.
They all said "Considering your age, surgery offers you the best chance of never seeing PCa again."
I think this info is out there pretty well for us guys who were in our 40's. While I never read a study, everywhere I turned said the same thing. So, it is nice to see the info I was given backed up by this article.
thanks
Paul
46 at Diagnosis.
Father died of Pca 4/07 at 86.
1/06 PSA 3.15
1/07 PSA 4.6 (Biopsy 3/07 just suspicious)
10/07 PSA 5.06 (Biopsy 11/07 1 of 12 with 8% involvment) (1mm)
Da Vinci surgery Jan 5, '08 at Mt. Sinai Hosp. NYC www.roboticoncology.com
Saved both nerve bundles.
Path Report: Stage T2cNxMx
-Gleason (3+3)6
-totally contained to prostate,
-10% involvement in L & R Mid lobes
PSA 0 at nine months.
Pad free on March 14 - (10 weeks.) Never a problem since.
ED - Took 100mg viagra every night. for several months
Totally usable erections at 10 weeks, which disappeared over the course of a month or two.
ED bounce is what they call it. Now, at one year, ED is fine with viagra.
One year PSA - undectable!


Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 7701
   Posted 5/20/2009 6:00 PM (GMT -6)   
Here is a European study that concludes the same way. Except that it gives radiation better makrs that watchful waiting...


longevity.about.com/b/2007/12/08/best-treatment-for-prostate-cancer.htm

Then click on comparisons...



For some reason this link does not work. But if you copy and paste in in your browser it works fine.



Tony

That link is really messed internally. I tried to repost the original by going to the site manually and copying, but no go.

Post Edited By Moderator (James C.) : 5/20/2009 8:41:52 PM (GMT-6)


Squirm
Veteran Member


Date Joined Sep 2008
Total Posts : 692
   Posted 5/20/2009 6:43 PM (GMT -6)   
Tony that link doesn't work.

Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 7701
   Posted 5/20/2009 7:08 PM (GMT -6)   
Sqirm,
I'm not sure why it doesn't link directly. But if you cut and paste it in your browser, it works fine.

I'll see if I can figure this one out...

Tony
 Age 46 (44 when Dx)
Pre-op PSA was 19.8 : Surgery at The City of Hope on February 16, 2007
Geason 4+3=7, Stage pT3b, N0, Mx
Positive Margins (PM), Extra Prostatic Extension (EPE) : Bilateral Seminal vesicle invasion (SVI)
HT began in May, '07 with Lupron and Casodex 50mg (2 Year ADT)
IMRT radiation for 38 Treatments ending August 3, '07
Current PSA (May 11, 2009): <0.1
 
My Journal is at Tony's Blog  
 
STAY POSITIVE!


James C.
Veteran Member


Date Joined Aug 2007
Total Posts : 4453
   Posted 5/20/2009 9:44 PM (GMT -6)   
Tony, if you hover over the link and look at the bottom line of your browser, it shows the coding for it there. There is some extra html init, specifically <b>'s. That's whats wrong and it's built in the link.
James C. Age 62
Co-Moderator- Prostate Cancer Forum
4/07 PSA 7.6, referred to Urologist, recheck 6.7
7/07 Biopsy: 3 of 16 PCa, 5% involved, left lobe, GS 3/3=6
9/07 Nerve sparing open RRP- Path Report: GS 3+3=6 Stg. pT2c, 110gms, margins clear
21 mts: ED- 50 mg Viagra 3X week, pump daily,Trimix .35ml 2X week continues
PSA's: .04 each 3 months

New Topic Post Reply Printable Version
Forum Information
Currently it is Friday, October 31, 2014 4:46 AM (GMT -6)
There are a total of 2,256,100 posts in 250,951 threads.
View Active Threads


Who's Online
This forum has 157699 registered members. Please welcome our newest member, rdthydjdf.
176 Guest(s), 5 Registered Member(s) are currently online.  Details
sayyadina, Wrap_down_unde, THE HAPPY TURTLE, Utahgal, paulroy


Follow HealingWell.com on Facebook  Follow HealingWell.com on Twitter  Follow HealingWell.com on Pinterest  Follow HealingWell.com on YouTube
Advertisement
Advertisement

©1996-2014 HealingWell.com LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer