Father died from poorly differentiated PCa @ 78 - normal PSA and DRE
5 biopsies over 4 years negative while PSA going from 3.8 to 28
Dx Nov 2007, age 46, PSA 29, Gleason 4+4=8
Decided to participate in clinical trial at Duke - 6 rounds of chemo (Taxotere+Avastin)
PSA results: 1/8/2008-33.90, 1/11/2008-29.50, 1/31/2008-38.20,
2/21/2008-32.00, 3/13/2008-26.20, 4/3/2008-26.60, 4/24/2008-20.60
RRP at Duke (Dr. Moul) on 6/16/2008
Pathology: Gleason downgraded 4+3=7, Duke: T2c N0MX, one positive margin,
2nd opinion at Sloan Kettering: T3a N0MX, extraprostatic extension, two positive margins
PSA undetectable for 8 months, then 2/6/2009-0.10, 4/26/2009-0.17, 5/22/2009-0.20, 6/11/2009-0.27
6 Months ADT: Casodex started 6/12/2009, Lupron 6/22/2009
IMRT to start mid-Aug
Your responses have been a great help to me. I have been told that I have many options, and I am trying to do what everyone must think they can do - get rid of the cancer without any side effects. (From what I see it's pretty near impossible.) It just seems that robotic surgery is so invasive, and the recovery period so long - about 2 years I am told for complete return to what is considered acceptable. Luckily I have the time to wait until I accept that I have Prostate cancer, and that I must do something or risk a fate worse than the side effects of surgery.
Greetings, Paul. I would agree with my brothers here who have said there are very few doctors who would attempt salvage surgery after radiation. The radiation just does so much to the prostate bed that it is almost impossible and yes, there are lots of horror stories out there regarding those who have tried the surgery.
There is somewhat of a bias here on this board towards surgery - me included. Yes, there are side effects but don't assume they will be for 2 years. My doc advised me to be prepared for incontinence and impotence for 2 years, but neither have effected me very much right from the start. Sure, there are some issues but nothing that couldn't be dealt with.
You do have time so make a good decision and then don't look back. Do the research and once you have a treatment then do it and let the healing begin. David
64 years old.
PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DX BPH and continue to get biopsies yearly. Positive Biopsy in 10-08, 2 cores of 25, G6 less than 5%. Scheduled Surgery as recommended.
2nd Opinion from Dr Sholtz, an Oncologist said DX wrong, path shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G 4+3 approx 2.5cm diameter.
Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy.
Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and burining urination. Daily activities resumed day after implants.
Scheduled for 5 weeks IMRT in July