what does unifocal/multifocal mean?

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Veteran Member

Date Joined Nov 2009
Total Posts : 6096
   Posted 12/2/2009 4:13 PM (GMT -7)   
I was looking at one of those many PC calculators and it asked if the cancer was unifocal or multifocal. I'm not sure what that means. Does unifocal mean 1 positive core and multifocal >1, or are they talking about something else?
63 years old
PSA-- 3/08--2.90;  8/09--4.01; 11/09--4.19 (Free PSA 24%), this after 45 days on cipro! DREs have always been normal.
History of BPH/prostatitis.
PCA-3 test: 75.9
Biopsy on 11/30/09
Biopsy Report—Prostate Cancer

5 out of 12 positive

2 cores were 3+3 (I have to get the percentages) on one side

2 cores are 4+3 (5%)

1 core 3+4 (30%)

no peri-neural invasion

prostate is 45 grams

Stage: T1C


Veteran Member

Date Joined Jun 2008
Total Posts : 1803
   Posted 12/2/2009 4:33 PM (GMT -7)   
Compiler, multifocal means that there was cancer found in more than one area with unifocal meaning only one area had cancer. Prostate cancer is generally a multifocal disease. In fact, the average surgical specimen after prostatectomy contains 7 areas with cancerous cells.
Husband diagnosed in 2/2008 at age 57 with stage T1c. Robotic surgery performed 3/2008. Stage upgraded to T3a (single small EPE in posterior left). Perineural tumor infiltration present. Apex margin, bladder neck and SV negative. Final Gleason 3+4 SA. PSA: 0.0 til July 2009. August 2009 PSA was 0.1, in September it was 0.3 Met with radiation oncologist, CT scan and bone scan clean. Third PSA on October 16 - PSA BACK TO UNDETECTABLE! Next PSA scheduled for early December. No radiation treatment at this time!

Veteran Member

Date Joined Nov 2007
Total Posts : 598
   Posted 12/2/2009 4:38 PM (GMT -7)   
PCa was described to me as a Swiss Cheese disease. It starts all over the place all at the same time. Isn't that weird? It's as if some switch is turned on and it starts to go bad from the inside out.
46 at Diagnosis.
Father died of Pca 4/07 at 86.
10/07 PSA 5.06 (Biopsy 11/07 1 of 12 with 8% involvment) (1mm)
Da Vinci surgery Jan 5, '08 at Mt. Sinai Hosp. NYC www.roboticoncology.com
Saved both nerve bundles.
Path Report: Stage T2cNxMx
-Gleason (3+3)6
Pad free on March 14 - (10 weeks.) Never a problem since.
ED - at one year, ED is fine with viagra.
One year PSA - undectable!

ED Website: www.FrankTalk.org - frank discussions of Erectile Dysfunction - check it out.

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