biopsy results please translate..............................

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hightimes
New Member


Date Joined Dec 2009
Total Posts : 7
   Posted 1/18/2010 12:27 PM (GMT -6)   
Tlc Gleason 7 adenocarcinoma of the prostate
 
PSA 4.6. TRUS/bx cores - evaluate for malignancy
 
right lateral apex recieved in formalin is a 1.3 cm tan core (1ns)
 
right medial apex recieved in formalin is a  a 1.3 cm tan core (1ns)
 
right anterior (right lateral mid)  recieved in formalin is a 1.4 cm tan cor (1ns)
 
right medial mid recieved in formalin is 1.o cm tan core (1ns)
 
right lateral base recieved in formalin are two tan cores 0.2 to 1.2 cm (2ns)
 
right medial base recieved in formalin is a 1.2 cm tan core (1ns)
 
left lateral apex recieved in formalin is a 1.2 cm tan core (1ns)
 
left medial apex recieved....
 
My friends father took the results away from him before he could finish but this was what he was able to email to me.  we dont know anything about prostate cancer and are hoping someone could shed some light on what any of this means. 
 
Radiation treatment was given to him as an option, thus avoiding surgery at this time.  is this a good move or is surgery the correct decision.  i realize these are tough calls and are made by the physician and patient behind closed doors but any and all opinions regarding these above biopsy results would be greatly appreciated..
 
thx in advance

Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3217
   Posted 1/18/2010 1:04 PM (GMT -6)   
High,

You were just coming to the important stuff. Typically if you have a 12 needle biopsy there are 6 on one side and 6 on the other. The info you were typing was where each one was taken.
The kinds of numbers you want to see are: 0/12 positive. That means they did not find anything in 12 samples. From my signature you can see "7/12" so that means they found it in 7 out of 12. There is a second number If they found something, you might see 5% in for example: left lateral apex. It is better if that number is low. Again from my signature I had some that were 70%. Not the best. There are guys here that had 12/12 and 90%. Look at signatures.
Also you want to know the Gleason score. It would look like GS 3+3=6. That is important. I won't get into what it all means. You can easily find details on line. Lower gleason is better. 3+3 is a typical "nice" value(as if any PC value is "nice") 5+5 is the worst, bad.
So if you get a chance to see it again, look for something like:"2/12 positive, 10% , Gleason 3+3."
Good luck,
Jeff
DX Age 56. First routine PSA test on April 8th: 17.8. Start 2 weeks of Cipro to rule out protatitis.
May PSA: 22.6, 3 weeks later: PSA: 23.2.
Biopsy 6/10/09: 7/12 scores positive, Gleason 6=3+3. Bone scan and C/T scan negative.
RP DaVinci -7/21/2009 @ Univ of Roch Medical Center
Left nerve gone, right partial spared.
Catheter removed - 7/31/2009 Pathology report received:
Gleason 3+4=7, Tumor size: 2.5 x 1.8 cm, location: both lobes and apex.
Extraprostatic extension present; Perineural invasion: present, extensive.
No Malignancy in Seminal Vesicle, vasa deferentia, lymph nodes 0/13
Prostate mass 56 grams. Pathologic Stage: pT3aN0MX
Post Surgery Status:
Potency - 12/11 5 months, Still no activity, zip. Using pump daily since 11/11. No effect with 20 mg of Cialis or 100 mg of Viagra. Shots next? See Uro 1/20/10
Incontinence - 8/20 4 full pads per day
.. 9/7 3-4 full pads per day (Try cutting down on fluids. Bad idea. I know.)
11/14 4 months: Still 3 pads per day. 420ml/day, 91 um leak.
12/11 5 months: Still 3 pads per day. 400-450ml/day
1/11/10 6 months: Still 3 pads but leak is now 320 ml (5 day avg.)
Post Surgery PSA - 9/3 6 weeks - 0.05; 10/13 3 months - 0.04 undetectable.


Purgatory
Elite Member


Date Joined Oct 2008
Total Posts : 23847
   Posted 1/18/2010 1:28 PM (GMT -6)   
High, unfortunately, what you posted is too incomplete. The most important parts aren't shown, anyway you can a full copy and post the full results?

David in SC
Age: 57, 56 dx, PSA: 7/07 5.8, 7/08 12.3, 9/08 14.5, 10/08 16.3
3rd Biopsy: 9/08 - 7/7 Positive, 40-90% Cancer, Gleason 4+3
Open RP: 11/08, Rht nerves saved, 4 days in hospt, on catheters for 63 days, 5th one out 1/09
Path Rpt: Gleason 3+4, pT2c, 42g, 20% cancer, 1 pos margin
Incontinence:  1 Month     ED:  Non issue at any point post surgery
Post Surgery  PSA: 2/09 .05,5/09 .1, 6/09 .11. 8/09 .16
Post SRT PSA: 1/10 .12
Latest: 7/9 met 2 rad. oncl, 7/9 cath #6 - blockage, 8/9 2nd corr surgery, 8/9 cath #7 out 38 days, 9/9 - met 3rd rad. oncl., mapped  9/9, 10/1 - 3rd corr. surgery - SP cath/hard dialation, 10/5 - 11/27 IMRT SRT 39 sess/72 gys ,cath #8 33 days, Cath #9 35 days, 12/7 - Cath #10 in place


Casey59
Veteran Member


Date Joined Sep 2009
Total Posts : 3172
   Posted 1/18/2010 1:57 PM (GMT -6)   
Sean, in your earlier post you said that "late stage cancer" was mentioned by the doctor. While there is not enough information in what you provided here to tell, one positive note is that the two key measurements you did provide (PSA=4.6 and Gleason=7) COULD be associated with an advanced case, but are more likely associated with an intermediate stage. Sorry, but beyond that, more info is needed...

Tony Crispino
Veteran Member


Date Joined Dec 2006
Total Posts : 7582
   Posted 1/18/2010 2:06 PM (GMT -6)   
hightimes,
The core information you listed is only description of the core samples, not the pathological analysis of each sample. My report had this information you listed but also had a second section that looked like the following:

1> right lateral apex - shows stroma and normal normal glandular formation
2> right lateral base - 80% of sample is positive for adenocarcinoma (Gleason 4+3=7)

Etc.

You need to ask for the complete pathology report...

Tony
Prostate Cancer Forum Co-Moderator


hightimes
New Member


Date Joined Dec 2009
Total Posts : 7
   Posted 1/18/2010 3:43 PM (GMT -6)   

Ok guys.  really appreciate the feedback.  My friend's father apparently wants to keep his health issues to himself but he goes to work at 430 eastern and since we are only trying to help him Amin is going to go dig for the information at that time.  I will start a new thread, hopefully by 530 eastern or whenever we can get the report in full detail.  thanks for the posts.  I'll get another thread started ASAP.

thx again.

sean/amin...............


medved
Veteran Member


Date Joined Nov 2009
Total Posts : 959
   Posted 1/18/2010 4:28 PM (GMT -6)   
I know you are motivated by a desire to help your friend's father.  I admire your desire to do so, and there are people on this forum who are very knowledgeable and could provide good advice.  Still, it seems to me you should at least consider respecting the preference of your friend's father to keep his medical information to himself, and not have it posted -- even anonymously -- on an internet board.  Assuming your friend's father is mentally competent, it seems to me he probably has the right to make all decisions concerning his own medical condition, including when and where to ask for help.  Just a thought....
 
Best wishes,
 
 
Age 45.  Father died of p ca. 
My psa starting age 40: 1.4, 1.3, 1.43, 1.74, 1.7, 1.5
 

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