IMRT radiation long term side effects

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koperg
New Member


Date Joined May 2010
Total Posts : 2
   Posted 5/2/2010 5:38 PM (GMT -6)   
confused  I had Davinci a year ago...then 37 IMRT treatments starting in late OCT. During the course if IMRT to the present, I have had little in the way of side effects.
 
Have any of you had any long term side effects?  I have heard it can take up to 2 years before effects can surface.
 
Thanks for any response.
 
George

Galileo
Veteran Member


Date Joined Nov 2008
Total Posts : 588
   Posted 5/2/2010 6:31 PM (GMT -6)   
None here. I'm nearly 3 years out from salvage IMRT. ED from surgery was not worsened as far as I can tell. No incontinence from radiation, 99.9% dry.

I had a short term SE, radiation proctitis, but that is long gone.
Galileo

Dx Feb 2006, PSA 9 @age 43
RRP Apr 2006 - Gleason 3+4, T2c, NX MX, pos margins
PSA 5/06 <0.1, 8/06 0.2, 12/06 0.6, 1/07 0.7.
Salvage radiation (IMRT) total dose 70.2 Gy, Jan-Mar 2007@ age 44
PSA 6/07 0.1, 9/07 and thereafter <0.1
http://pcabefore50.blogspot.com


don826
Veteran Member


Date Joined May 2008
Total Posts : 763
   Posted 5/2/2010 6:33 PM (GMT -6)   
Hello George,

I completed 45 IMRT treatments on 9/11/2008. The only side effect that I might attribute to RT is erectile disfunction. I am also on HT so I am not entirely sure that all of the problem is from the RT. I have not tried any of the ED drugs available. Have had modest erections on a couple of occassions but nothing to brag about. Other than that one issue I have gone about my life as before the treatment.

You are correct about the time frame for side effects to show up. I was told 18 to 24 months and I am between those two benchmarks. So far so good.

Best to you.
Don
Diagnosed 04/10/08 Age 58 at the time
Gleason 4 + 3
DRE palpable tumor on left side
100% of 12 cores positive for PCa range 35% to 85%
Bone scan clear and chest x ray clear
CT scan shows potential lymph node involvement in pelvic region
Started Casodex on May 2 and stopped on June 1, 2008
Lupron injection on May 15 and every four months for next two years
Started IMRT/IGRT on July 10, 2008. 45 treatments scheduled
First 25 to be full pelvic for a total dose of 45 Gray to lymph nodes.
Last 20 to prostate only. Total dose to prostate 81 Gray.
Completed IMRT/IGRT 09/11/08.
PSA 02/08 21.5 at diagnosis
PSA 07/08 .82 after 8 wks of hormones
PSA 10/08 .642 one month after completion of IMRT, 6 months hormone
PSA 03/09 .38 six months post radiation and nine months into hormones
PSA 06/09 .36 or .30 depending on who did the test
PSA 09/09 .33 one year after IMRT and 16 months into hormone
PSA 03/10 .32 18 months after IMRT Still on hormones


koperg
New Member


Date Joined May 2010
Total Posts : 2
   Posted 5/2/2010 6:50 PM (GMT -6)   
Thanks for the reply Galilio& Don.........my last PSA was 0.1 so I am optimistic.........ED has reared its ugly head...............but at age 66...........I'm happy thats the only problem.

Best to all,
George

JB71
Regular Member


Date Joined Nov 2009
Total Posts : 202
   Posted 5/3/2010 9:28 AM (GMT -6)   
Hope my results will be similar. Already on HT since November, had open surgery in January and will be starting IMRT next Monday, May 10.
 
ED has been a problem for a year but at 71, I'm not too concerned about that right now.

Post Edited (JB71) : 5/3/2010 10:41:48 AM (GMT-6)


randy2
New Member


Date Joined Feb 2012
Total Posts : 3
   Posted 9/25/2013 7:56 PM (GMT -6)   
I am nearly 6 months after IMRT w/o HT and although ejaculation is clear and viscous, ED has not reared it's "ugly" head...as it were! I'm 74 and still able to "get it up"! I feel so fortunate. My partner is happy also. To all you great guys who are going through worse than I am...keep the faith and "keep on truckin'". Last PSA went from 9.5 to 2.6 in three months. Another PSA in early October. Cheers
Albert

Redwing57
Veteran Member


Date Joined Apr 2013
Total Posts : 856
   Posted 9/25/2013 8:25 PM (GMT -6)   
Just finished IGRT a month ago, so I'm interested too in the long term effect reports! Four months on ADT2 with really good initial results, <0.1, for 2 years total planned.

The little guy is still functional with some focused attention, but with dry orgasms. Different, but quite intense. No idea what's created by what yet, but I imagine most of what's happening right now is from the ADT.
IGRT by IMRT, 44 done 8/28/13: 50.4 Gy pelvic nodes, 79.2 Gy prostate
ADT2 2 yrs: Lupron 5/1/13+Casodex 6/25/13

Age 55 @ Dx 4/16/13-
Bx 6/12 pos all on rt G9=5+4 (80%, 60%), 4+5 (2 at 100%, 80%, 10%), PNI confirmed
3T MRI: Bilateral EPE, NVB+, SV-, LN-, cT3

Date PSA fPSA
8/13 <0.1 (ADT, post-RT)
6/13 9.7
3/13 5.2 12% PCA3=31
9/12 4.1 15%
history since 2002 high/varying PSA, 3 neg bx

InTheShop
Veteran Member


Date Joined Jan 2012
Total Posts : 3027
   Posted 9/25/2013 9:16 PM (GMT -6)   
I am about a year and a half out from IMRT. So far SE not bad. Hemorrhoids are acting up a bit more. A little urgency from time to time and a bit of ED (the pills help).

Andrew
I'll be in the shop.
Age 53
PSA 4.2 10/11, 1.9 6/12, 1.2 12/12, 1.0 5/13
GS 3+4
Stage T1C
2 out of 14 cores positive
Treatment IGRT - 2/2012
My latest blog post

Bohemond
Regular Member


Date Joined Apr 2012
Total Posts : 388
   Posted 9/25/2013 9:56 PM (GMT -6)   
I began having rectal bleeding about 8 months after SRT ended. This was a few times per week at first and gradually diminished over a period of 10 months or so until things returned to more-or-less normal.

I also had uncomfortable, but manageable urinary urgency during the last half of my treatment and for a few weeks afterward. This was especially when first standing up, but receded after a minute or two on my feet.
Age 67
-DX March 2002 - PSA 9.4, needle biopsy PCa 5 of 10 cores positive - 30-50%.
-RP April 2002. Pathology PT3B N0 MX Gleason=7 (3+4), 75% left lobe; small focus right lobe; lymphatic/vascular invasion.
-Post-surgery PSA low of 0.01; slow rise to 0.4 (August 2009).
-SRT Jan/Feb 2010. Enlarged lymph node near prostate bed targeted. Casodex 3 months during SRT
-PSA 0.00 Apr 2013
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