impact of coffee or alcohol on PSA

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medved
Veteran Member


Date Joined Nov 2009
Total Posts : 963
   Posted 7/26/2010 1:17 PM (GMT -6)   
I read a couple of articles on websites today suggesting that coffee or alcohol consumption can affect psa results.  For example, one site, which was linked on the Yannow site, stated:  "Alcohol and Coffee: Both can irritate the prostate and should be avoided for 48 hours prior to blood being drawn."    I had never heard that before.  Have any of you received that advice, or otherwise looked into this?
 
Even if this is true, I am wondering whether I should follow this advice.  My reasoning:  PSA trends may be more important than absolute values, and I have not abstained from coffee or alcohol in advance of prior PSA tests.  So maybe better not to do so in the future either, so that my results are comparable.  (Same idea as using the same lab/assay).
 
Thoughts?
 
 
Age 46.  Father died of p ca. 
My psa starting age 40: 1.4, 1.3, 1.43, 1.74, 1.7, 1.5, 1.5
 


Steve n Dallas
Veteran Member


Date Joined Mar 2008
Total Posts : 4004
   Posted 7/26/2010 2:24 PM (GMT -6)   
I've never been told to NOT doing anything before a PSA test.
 
And I can't get out of bed without my coffee...
Age 55   - 5'11"   215lbs
Overall Heath Condition - Good
PSA - July 2007 & Jan 2008 -> 1.3
Biopsy - 03/04/08 -> Gleason 6 
06/25/08 - Da Vinci robotic laparoscopy
05/14/09  - 4th Quarter PSA -> less then .01
11/20/09 - 18 Month PSA -> less then .01
05/18/10 - 24 Month PSA -> less then .01
Surgeon - Keith A. Waguespack, M.D.


John T
Veteran Member


Date Joined Nov 2008
Total Posts : 3703
   Posted 7/26/2010 3:13 PM (GMT -6)   
I don't know what affect that alcohol and caffine have on psa, but I doubt that it is much. As Medved said the real value of psa is how it reacts over time; this can tell us a lot about our pc, much more than just one reading.
PSA can fluctuate about 25% from day to day; If you don't believe this go on Yannow and see the test that Terry Hurber ran, taking psa tests daily for 30 days. The daily fluctuations are remarkable and anyone who would even think of making a decision based on only one or two psa tests should look at Terry's little test.
JohnT

64 years old.

PSA rising for 10 years to 40, free psa 10-15. Had 5 urologists, 12 biopsies and MRIS all neg. Doctors DXed BPH and continue to get biopsies yearly. 13th biopsy positive in 10-08, 2 cores of 25, G6 less than 5%. Scheduled for surgery as recommended by Urological Oncologist.

2nd Opinion from Dr Sholtz, a Prostate Oncologist, said DX wrong, pathology shows indolant cancer, but psa history indicates large cancer or metastasis. Futher tests and Color Doppler confirmed large transition zone tumor that 13 biopsies and MRIS missed. G7, 4+3, approx 16mmX18mm.

Combidex MRI in Holland eliminated lymphnode mets. Casodex and Proscar reduced psa to 0.6 and prostate from 60mm to 32mm. Changed diet, no meat and dairy. All staging tests indicate that tumor is local and non agressive. (PAP, PCA3, MRIS, Color Doppler, Combidex, tumor reaction to diet and Casodex, and tumor location in transition zone). Surgery a poor option because tumor is located next to the urethea and positive margin is very likely; permanent incontenance is also high probability with surgery.

Seed implants on 5-19-09, 3 hours door to door, no pain, minor side affects are frequency and urgency; very controlable with Flowmax and lasted 4 weeks. Daily activities resumed day after implants with no restrictions. Gold markers implanted with seeds to guide IMRT.

25 treatments of IMRT 6 weeks after seed implants. No side affects at all.

PSA at end of treatment 0.02 mostly the result of Casodex. When I stop Casodex next week expect PSA to rise. Next PSA in November. Treatments and side affects have greatly exceeded my expectations. Glad to have this 11 year journey finally conclude.

JohnT


NotHard
Veteran Member


Date Joined Mar 2009
Total Posts : 737
   Posted 7/26/2010 5:40 PM (GMT -6)   
If the alcohol and coffee I drink, can find my prostate, they can irritate the hell out of it, if they like .lol................Kev
Age 52yrs
6 out of 8 cores positive 3 X 60% / 3 X 10%
PSA 4 Gleason Score 3+4=7 Stage T1c
Robotic Surgery 24/12/08
Upgrade Gleason Score 4+3=7 Gleason Differential 60%/40%
Stage T2c Three small foci total volume <10%
Neg Margins and Nodes
Nil - Extraprostatic Extentions
Dry less than 1 week. ED- okay with Meds.
PSA at 18mths no change remains 0.03
"Everyday in Everyway I get better"


T40
Regular Member


Date Joined Oct 2009
Total Posts : 103
   Posted 7/26/2010 6:41 PM (GMT -6)   
I think the effect would be minimal.
Age 40
Pre-op PSA was 5.8 from wellness test on May 19, 09
Follow up test from uro was 4.6 with a 9.3% free psa
Gleason 3+3 in one core, 3+4 in second core of 12 samples taken
Surgery performed August 19th, 09.
One side nerves spared. Nerve graft on other side.
Six weeks incontinence almost over. ED a work in progress but seeing some response.
4 months no longer using pads. ED using trimix with positive response.
Post op October 2nd, 2009 All margins were negative. PSA results in a few days.
Post op pathology 3+4 PT2A NOMO
6 wk PSA .004
3 month PSA .003 12-18-09
6 month PSA .003 3-17-10


goodlife
Veteran Member


Date Joined May 2009
Total Posts : 2612
   Posted 7/26/2010 9:14 PM (GMT -6)   
May be if you drink caffeinated coffee before you go to bed, you might be inclined to do the big no-no with the mrs. as you lay there wide awake.

Like Kev, not my problem anymore.
Goodlife
 
Age 58, PSA 4.47 Biopsy - 2/12 cores , Gleason 4 + 5 = 9
Da Vinci, Cleveland Clinic  4/14/09   Nerves spared, but carved up a little.
0/23 lymph nodes involved  pT3a NO MX
Catheter and 2 stints in ureters for 2 weeks .
Neg Margins, bladder neck negative
Living the Good Life, cancer free  6 week PSA  <.03
3 month PSA <.01 (different lab)
5 month PSA <.03 (undetectable)
6 Month PSA <.01
1 pad a day, no progress on ED.  Trimix injection
No pads, 1/1/10,  9 month PSA < .01
1 year psa (364 days) .01
15 month PSA <.01


JLW1974
New Member


Date Joined Jul 2010
Total Posts : 7
   Posted 7/27/2010 1:38 PM (GMT -6)   
I read somewhere that having sex or the "release of semen by other means" within 24 hours of a PSA test can slightly increase PSA levels.

Post Edited (JLW1974) : 7/27/2010 12:45:27 PM (GMT-6)


goodlife
Veteran Member


Date Joined May 2009
Total Posts : 2612
   Posted 7/27/2010 9:30 PM (GMT -6)   
That was my point of the "big no-no" before a PSA draw.
Goodlife
 
Age 58, PSA 4.47 Biopsy - 2/12 cores , Gleason 4 + 5 = 9
Da Vinci, Cleveland Clinic  4/14/09   Nerves spared, but carved up a little.
0/23 lymph nodes involved  pT3a NO MX
Catheter and 2 stints in ureters for 2 weeks .
Neg Margins, bladder neck negative
Living the Good Life, cancer free  6 week PSA  <.03
3 month PSA <.01 (different lab)
5 month PSA <.03 (undetectable)
6 Month PSA <.01
1 pad a day, no progress on ED.  Trimix injection
No pads, 1/1/10,  9 month PSA < .01
1 year psa (364 days) .01
15 month PSA <.01


newtopc
Regular Member


Date Joined Dec 2009
Total Posts : 57
   Posted 7/28/2010 9:32 AM (GMT -6)   
I think both irritate the prostate. I went in for my PSA test after a three day "hunt camp", more of a drinking camp, my liver count was way up in all categories and my PSA jumped .60. I went back for a new test and abstained from everything  for 7 days and my PSA dropped .66 and liver went close to normal. I will be posting new results under separate cover today. I abstained  for 4 days prior to all the same tests. Waiting for my doctor to call right now. Praying PSA has not gone up.
47 Year old male, smoker, healthy
Routine physical May 12, 2009, PSA 4.12
Follow up PSA October 27, 2009, PSA 4.61 / Free PSA 4% (Not good)
Referral to Urologist Feb 18, 2010
Follow up PSA January 7, 2010, PSA 3.95, Free PSA 4% (still not good)
Biopsy March 16th, 2010, 8 core samples taken, Results April 5, 2010
Results - very small prostate, DRE normal, all core samples negative, follow up PSA July, results Aug 2nd 2010

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