63 years old . PSA-- 3/08--2.90; 8/09--4.01; 11/09--4.19 (Free PSA 24%), after 45 days on cipro! DREs have always been normal. PCA-3 was about 75 (way above the 35 threshold). That led to:
Biopsy on 11/30/09. 5 out of 12 cores positive. Gleason 4+3. 2 cores were 3+3 (one 5% and the other 30%) on one side. On other side:2 cores are 4+3 (5%)--1 core 3+4 (30%) no peri-neural invasion. prostate is 45 grams. Stage: T1C.
Surgery with Dr. Menon at Ford Hospital, 1/26/10. He says all looked good. Spared nerves. Unfortunately: Pathology Report: G 4+3 (65%-35%). Cancer in 15% of gland. Lymph Nodes: Clear. Perineural Invasion: yes. Seminal Vessical Involvement: No. Extraprostatic Extension: yes. Positive Margin: Yes-- focal-- 1 spot .5mm. Final Weight is 52.7 gms. (Second opinion from Jon Epstein at Hopkins confirmed these results)
Incontinence: joined that club-- definite leaks—1 pad/day. Night is dry, was using 1 pad at night for security, but pretty much dispensed with that most nights. Update: no pads at night. No pads while at home, but still very uncomfortable. Use 1 pad for out-of-house activities. Suddenly got MUCH better on 3/10/10, almost overnight. Still some urgency but no pads about 90% of the time. As of 3/12/10--completely continent! Uh...OH. As of about 3/16/10 problems with constant urgency although no pads needed--feels like an infection but none showing in urine.
Update: since late March all is well in that area. I would say 99.9% continent (a spurt here and there, maybe 5 spurts per week). As of 6/22/10, I would say I am 100% continent, but I do have (controllable) significant urgency.
First post-op PSA on 3/10/10--DRUM ROLL: 0.01 Next PSA in mid-June.
Second post-op PSA on 6/21/10--0.02--Not too bad!
Post Edited (Arch) : 8/24/2010 7:45:38 PM (GMT-6)