side effects - or harms of POMx and flexeed pills?

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ein
Regular Member


Date Joined Jan 2012
Total Posts : 75
   Posted 2/27/2012 4:43 AM (GMT -6)   
In another thread Bob has mentioned POMx pills and flexeed pills are helping him. I don't know how much will it help and am neither denying it nor accepting it - but I wanted to ask the forum - is there any "harm" in taking those?

i.e. are there any known side effects in old age from these? If not - I would like to start it along with my multivitamin and Vitamin D pills.

What are your recommendations against it?

Thanks
Ein

Steve n Dallas
Veteran Member


Date Joined Mar 2008
Total Posts : 3980
   Posted 2/27/2012 6:28 AM (GMT -6)   
There are dozens of threads on the subject. But, I would Google both and read about the side effects etc..

SpecialLady
Veteran Member


Date Joined Nov 2011
Total Posts : 858
   Posted 2/27/2012 8:29 AM (GMT -6)   
From what I have read pomegranate capsules are extremely safe, my father is taking 500mg daily. Flaxseed oil was criticized by Dr.Myers (he wrote a book about it) in that Omega-3 fatty acids in this oil are not processed well by a male organism, basically he called it a useless source of Omega-3. He recommends fish, instead. On the other hand, flaxseed itself (the whole seed) does have some lignans that have been proven to have some benefit against prostate cancer, but again, not sure how strong this evidence is.
Father (69 now) diagnosed with PCs in Jan 2011: PSA 7.5, Gleason 3+3, two inconclusive bone-scintigraphies, MR scan showed 2 bone mets. Started hormonal therapy (Trelstar+Casodex) in Jan 2011. Added Zometa in January 2012.

robertC
Veteran Member


Date Joined May 2011
Total Posts : 937
   Posted 2/27/2012 8:46 AM (GMT -6)   
Some studies have found that multivitamins are statistically harmful.
Gleason (3+4) 7, PSA 5 in November 2011 age 63
cryoablation in January 2011.
April 29 2011 psa undetectable.
January 2012 psa .05 detectable

Casey59
Veteran Member


Date Joined Sep 2009
Total Posts : 3172
   Posted 2/27/2012 10:07 AM (GMT -6)   
 
 
ein said...
What are your recommendations against it?
 
 

Ein, just a brief comment on your post.  I’m not a medical researcher and I don’t give “recommendations,” but I’ll give you the commonly available wisdom for PC…

If you want to use flaxseed, use the whole ground flaxseed and not the flaxseed oil.  The whole flaxseed is an outstanding plant source of omega-3 fatty acids and lignans which produces phytoestrogens (protective against prostate cancer), and increases apoptosis (cancer cell death).  A tablespoon of ground flaxseed per day is typical; but forego the oil.  HERE’s a Mayo Clinic reference FYI.

Be careful of overdoing multivitamins.  The problems seem to lie in some of constituent components; calcium, for example, in amounts exceeding 2000 mg daily have been associated in multiple studies with elevated risk of PC.  Vitamin D is beneficial, but mega-dosing not under a doctor’s care can be bad for PC.  Many PC specialists are recommending against multivitamins, and recommend taking a daily maintenance dose of Vit D instead.

I’ve seen absolutely no harms in pomegranate published…only benefits (in many areas, including PC).

 

What most doctors recommend, and what I personally try to follow, is to use supplements as supplements.  Try hard to eat an intelligent, colorful diet.  Reduce or eliminate animal fats (fatty red meats and high-fat diary, which both stimulate prostate cancer growth).  Avoid transfats.  Use olive oil instead of corn or canola oil.  Increase fresh fish intake (avoid fried fish).  Enjoy tomato products (high in lycopene), which includes pizza souce, tomato paste and ketchup.  Increase fresh fruit, herb and vegetable consumption…think “color.”  And lastly, enjoy a glass or red wine daily, or grape juice, or pomegranate juice.

 

Bon appétit!


Mitch128
Regular Member


Date Joined Aug 2010
Total Posts : 78
   Posted 2/27/2012 1:58 PM (GMT -6)   

Ein,

I agree with the previously posted comments re: POMx. I've been taking 1000mg daily for the last year or so with no adverse side-effects. I also took 5000 IU of Vitamin D-3 daily until my Hydroxy D levels rose to within normal levels. The dosage has now been reduced to 5000 IU twice a week.

 

Again I agree with the previously posted comments re: Multivitamins. As an example, Centrum Ultra Men's Multivitamin supplement contains 150% of the daily allowance (45 IU) of Vitamin E which, if taken, would be diametrically opposed to my hormonal therapy goals of reducing testosterone, not encouraging its production. I'm sure this same situation applies to many of our forum members who, for instance, have been chemically castrated by Lupron and/ who are on a continuing hormonal therapy program.

 

BTW, Dr. "Snuffy" Meyers has consistently referred to Resveratrol as the single-most important supplement for men with PCa. On his recommendation, I have been taking 100 mg daily for the last year or so. Not sure if Resveratrol is offered at chain pharmacies, but it can be ordered online from Swanson. 

 

Hope this helps,

 

Mitch in SC


Carlos
Regular Member


Date Joined Nov 2009
Total Posts : 469
   Posted 2/27/2012 2:36 PM (GMT -6)   
Ein,  Johns Hopkins conducted a small study on POMx.  They compared a 1000mg dose to a 3000mg dose over 18 months.  Mild to moderate diarrhea was seen in 8 pts (almost all were on the higher dose of POMx.)  No other side effects were reported.
 
Carlos

F8
Veteran Member


Date Joined Feb 2010
Total Posts : 3208
   Posted 2/27/2012 2:50 PM (GMT -6)   
I just received my 8th 90-day supply of pomx capsules from Pom. I plan to take them for the duration.

ed
age: 56
PSA on 12/09: 6.8
gleason 3+4 = 7
HT, BT and IGRT
received 3rd and last lupron shot 9/14/10
2/8/11 PSA <.1, T= 6 ng/dl
6/8/11 PSA .2, T = 540 ng/dl
8/19/11 PSA .3, T = 487 ng/dl
10/5/11 PSA .2, T = 530 ng/dl

Casey59
Veteran Member


Date Joined Sep 2009
Total Posts : 3172
   Posted 2/27/2012 4:33 PM (GMT -6)   
http://i1142.photobucket.com/albums/n618/59Casey/2-18-201112-10-13PM.jpg

Added the above image as a "supplement" to my last post. My personal approach is to try to have at least one of the three on the left of this chart every day. I have pomegranate supplements, but don't take them every day. I had a Welch's 100% Concord Grape juice with lunch today (I keep them in my desk drawer), and I have a glass or so of red wine several nights per week, and I supplement with POM on days when I do neither (actually, on the morning after).

Jerry L.
Veteran Member


Date Joined Feb 2010
Total Posts : 2349
   Posted 2/27/2012 4:52 PM (GMT -6)   
The only side effect I've had to any of the usual suspects is my wallet seems lighter.
11/09 Dx at Age 44
12/09 DaVinci Surgery
1/10 T3b, G9
2/10 Adj. Radiation
3/11 PSA Rise/Scans/Spot on Pelvic Bone
4/11 HT / XGEVA
5/11 Spot Radiation
12/11 Scans - No new spots; spot is less intense / decrease in uptake

PSA History:
-----------------
'05 - .75
11/09 4.3 - 4.8
2010 <.05 (after surg&adj rad)
3/11 .09
4/11 .06
10/11 <.05
11/11 <.01
12/11 <.01

142
Forum Moderator


Date Joined Jan 2010
Total Posts : 5844
   Posted 2/28/2012 12:54 AM (GMT -6)   
I've been drinking Pom 100% juice as an alternative to orange juice since surgery, which does truly ugly things to my bladder.
 
My PSA is rising (doubling at 50 days), and my wallet is lighter, so pom is of no apparent value to me. And the task sucks.
 
Not sure whether I meant to say the task of drinking Pom sucks, or that the taste sucks. Both are true, in my opinion.

Post Edited (142) : 2/28/2012 7:18:48 AM (GMT-7)


ein
Regular Member


Date Joined Jan 2012
Total Posts : 75
   Posted 2/28/2012 8:21 AM (GMT -6)   
142 said...

My PSA is rising (doubling at 50 days).

Sorry - I never appreciated that fact from your posts in my last 2 months here. I always assumed that your PSA is in check after the radiation.

Jerry L.
Veteran Member


Date Joined Feb 2010
Total Posts : 2349
   Posted 2/28/2012 10:15 AM (GMT -6)   
142,

In your honor, I just rolled down my window and yelled some nasty language out the window about this disease. Once I rolled up the window, I reminded myself of all the miles still left to be travelled. Lots of options (new and old).

Jerry L.
11/09 Dx at Age 44
12/09 DaVinci Surgery
1/10 T3b, G9
2/10 Adj. Radiation
3/11 PSA Rise/Scans/Spot on Pelvic Bone
4/11 HT / XGEVA
5/11 Spot Radiation
12/11 Scans - No new spots; spot is less intense / decrease in uptake

PSA History:
-----------------
'05 - .75
11/09 4.3 - 4.8
2010 <.05 (after surg&adj rad)
3/11 .09
4/11 .06
10/11 <.05
11/11 <.01
12/11 <.01

Post Edited (Jerry L.) : 2/28/2012 8:19:21 AM (GMT-7)

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