imtls, I cannot directly answer your question with a “yes” or “no,” and I suspect that a clear answer to this narrow question is unknown today, but I suspect that there might be only marginal differences (but I doubt this aspect has been studied in depth). The bigger differences is likely from those who take pomegranate of any variety versus those who don’t take pomegranate to help slow PC progression.
I’m guessing that you are already aware that at last year’s American Society of Clinical Oncologists (ASCO) conference, the findings of the pomegranate/PC benefits under study in a Phase II trail (by Dr Michael Carducci from highly respected Johns Hopkins) were judged to be so important that they adjusted the conference schedule to allow for oral presentation of interim results. The Carducci study was independent confirmation of the favorable impact on slowing PSADT as a measurement of PC progression. (A number of study participants actually had their PSAs decline.)
This news from ASCO was exciting and wonderful news to the prostate cancer community!!!
To your original question, imtls, one thing for you to be aware of that I’ve read is that if you are using a pomegranate blend is to make sure it is 100% pure, with no added sugars, as the added sugars can take away from the antioxidant effect. A lot of guys here take the pomegranate extract pills instead of the juice for various reasons: to avoid sugars, don’t like the juice taste (that’s my reason #1), easier to regulate daily intake (my reason #2), etc.
Sounds like you have a sharp doc…one who keeps up-to-date with the newest information on prostate cancer care! Good for him/her, and more importantly good for you!
Many docs are recommending pomegranate because it’s high antioxidant index – it’s often called a “Super Antioxident.” Lots of non-PC related health benefit studies have been published—you can read-up on the benefits to heart disease (the #1 killer of men with PC), diabetes regulation benefits, and added protection from several cancers…but for you, and your doctor, and most the other men here at HW it is the pomegranate’s chemoprevention/anticancer effect on PC that it the very exciting news for all of the PC community! [Want to learn more details about pomegranate and differentiation (ability of PC cells to revert to their normal counterparts)? You can find scholarly work published HERE.]
Beyond the general recommendation, increasingly you will find the docs that specialize on treating PC are specifically recommending pomegranate for advanced case patients who seek to increase their chances against PC metastasis (those that seek to “stack the odds in their favor,” as I like to phrase it).
For example, Dr Nicholas Vogelzang (several guys here at HW see him, and he is chair and medical director of the developmental therapeutics committee at US Oncology in Las Vegas) was interviewed after the ASCO announcement (the one I previously mentioned, above); he called the impact of the study which confirmed results from previous studies “dramatic.” In his practice, he “recommends pomegranate extract or juice a lot,” typically for men with rising PSA levels.
imtls, while you won’t really know how much impact the pomegranate has in your own complex body/system (everyone responds differently to every type of medication), you know that you have science on your side in helping do your part to fight against increasing PSA. Best wishes!!
Post Edited (Casey59) : 4/24/2012 2:51:56 PM (GMT-6)
Post Edited (FoxRun) : 4/26/2012 8:58:46 AM (GMT-6)