New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

shipper12
Regular Member


Date Joined Mar 2012
Total Posts : 110
   Posted 6/5/2012 10:19 AM (GMT -6)   
I have a few questions about Trimix dosage.
 
I know it varies, but what is the average dose most men use?
 
Does the size of the dose vary depending where you inject? I notice I get better results on a lower dose when I inject on the right side near the base.
 
Does the size especially the thickness of the penis when flaccid have a bearing on the size of the dose?  Some men who use very small doses told me they very small when flaccid.

James C.
Veteran Member


Date Joined Aug 2007
Total Posts : 4452
   Posted 6/5/2012 11:45 AM (GMT -6)   
If I were making a WAG, I'd say between .1 and .2 (10 units to 20 units) is probably the most common amount. Some lucky guys use much less, so of us unfortunate ones use more. There seems to be no relation to injection point and results, but the whole process of injecting does have a lot of variations from one time to the next, seems like.
James C, 65, A Better Man, Injections? Read This
4/07: PSA 7.6, 3/16 PCa, 5% inv, lf. lobe, GS6
9/07: open RP, Path: pT2c, 110 gms., Prob. micro.inv.-left apical margin -GS6
4 Yrs: .04 'til 4/10-.06, 12/10-.09, 5/11-.08, 9/11-.14, 2/12-.10

Post Edited (James C.) : 6/5/2012 10:48:44 AM (GMT-6)


shipper12
Regular Member


Date Joined Mar 2012
Total Posts : 110
   Posted 6/5/2012 12:00 PM (GMT -6)   
James;;
 
I think your assessment is right.  I use .15 (15 units) and I get a very hard erection in 5 mins which lst for 2 hours. How lng have you been using Trimix?

James C.
Veteran Member


Date Joined Aug 2007
Total Posts : 4452
   Posted 6/5/2012 12:19 PM (GMT -6)   
Off and on, varying between bimix and trimix for 4 1/2 yrs. No problems so far.

Im_Patient
Veteran Member


Date Joined Aug 2009
Total Posts : 523
   Posted 6/5/2012 2:38 PM (GMT -6)   
There are varying strengths that docs prescribe, depending on their expectations of your need for help. Therefore, it is difficult to identify an amount to inject. After SRT, I had to ask for increasing strengths and inject larger amounts until I decided that it was better to take a different approach and went for an implant.

As long as you inject into the corpus cavernosum cavities, which span from the base to far up the shaft, the amount should not make a difference, since the medicine passes through the cavities pretty readily. Ditto for the size - it should more be dependent on what you will require given your condition, rather than the state of things. That said, if you are partially where you want to be without supplementation, I would be inclined to inject less than your normal dose.
Gleason,3+4;PSA 9.8,Nerve-sparing RRP,03/2008(Age 48 then),pT2c, 60g, neg margins; perineural & lymphatic invasion;3 lymph nodes removed,clear; seminal vesicle invasion:absent;Gleason 4 was 5-10%; PSA <0.1 until Oct 09:0.1; retest <0.1; scans clear;monthly results from Jan 2010:0.2,.2,.17,.17,.24,.31,.29,.41, IGRT SRT started 8/4/2010, PSA@5 weeks in: .17,after:.12,.10,.06, .05 since

Im_Patient
Veteran Member


Date Joined Aug 2009
Total Posts : 523
   Posted 6/5/2012 2:40 PM (GMT -6)   
shipper, if you are hard to your satisfaction for 2 hours, that sounds like you are injecting an optimal dose - that is where you want to be (something that sustains long enough, but does not get close to the 4 hour limit).
Gleason,3+4;PSA 9.8,Nerve-sparing RRP,03/2008(Age 48 then),pT2c, 60g, neg margins; perineural & lymphatic invasion;3 lymph nodes removed,clear; seminal vesicle invasion:absent;Gleason 4 was 5-10%; PSA <0.1 until Oct 09:0.1; retest <0.1; scans clear;monthly results from Jan 2010:0.2,.2,.17,.17,.24,.31,.29,.41, IGRT SRT started 8/4/2010, PSA@5 weeks in: .17,after:.12,.10,.06, .05 since

Tigerfan53
Veteran Member


Date Joined Jan 2011
Total Posts : 790
   Posted 6/6/2012 12:02 AM (GMT -6)   
Dr. Mulhall says the maximum duration should not exceed 90 minutes.
The minimum is 10 minutes.
The ideal is between 15 and 30 minutes.
If you get to 2 hours you should take steps to get it back down (below penetration hardness).

I agree with Im_Patient that size and location do not affect the dose, but rather what you need for your condition.
Diagnosed Dec 2010 at age 53
09/2010 PSA 4.8
11/2010 PSA 5.1
11/2010 PSA 5.3 after antibiotics
12/2010 Biopsy: 50% in 1 of 12 cores, PIN, G6, T1c
03/2011 PSA 5.6
06/2011 RALP negative margins, G6, pT2b, PIN, PNI, EPE
09/8/2011 PSA < 0.05
12/8/2011 PSA < 0.05

shipper12
Regular Member


Date Joined Mar 2012
Total Posts : 110
   Posted 6/6/2012 9:58 AM (GMT -6)   
I found that after I ejaculate and stay in bed awhile my erection starts to subside. However, If I get up and walk around, it comes back and Im still capable of penetration. Ive don't this before and my wife said i was just as hard the second time.
 
Also how flaccid should you be by the 2 hour limit? Although Im not hard enough to penetrate, my penis is much larger for quite awhile than it is in its normal flaccid state. I must add that I grow quite a bit when erect so Im very small when flaccid.
 
I also take 4 30mg Sudafed if necessary  
 
Any comments or suggestions?

Steve n Dallas
Veteran Member


Date Joined Mar 2008
Total Posts : 3985
   Posted 6/6/2012 10:25 AM (GMT -6)   
Do you automatically take the Sudafed or do you just have it handy? I wouldn't auto take it...

shipper12
Regular Member


Date Joined Mar 2012
Total Posts : 110
   Posted 6/6/2012 12:56 PM (GMT -6)   
No I only take it if Im not down in 2 hours. Its hard to gage as whats "dpwn" for me because i still remain large:

142
Forum Moderator


Date Joined Jan 2010
Total Posts : 5846
   Posted 6/6/2012 1:19 PM (GMT -6)   
Interesting discussion on the Sudafed. Never had that one with the uro, he just gave me instructions on which ER to go to, and put a flag in their system as to contact priorities.
 
Over time I've thought "maybe he missed that", but as I was looking at some of my files getting ready for the next visit, I realized that of course my severe allergy to Sudafed is listed in the medical record, so why would he tell me to take something that would kill me? Seems my uro pays attention to all the info I give them. 
Moderator - Prostate Cancer
(Not a medical professional)

DaVinci 10/2009
My adjuvant IGRT journey (2010) -
www.healingwell.com/community/default.aspx?f=35&m=1756808

shipper12
Regular Member


Date Joined Mar 2012
Total Posts : 110
   Posted 6/6/2012 2:02 PM (GMT -6)   
My urog gave me written instructions that were prepared by Sloan Kettering in NYC for PC patients who inject. It says that after 3 hours to take  4 30g regular strength Sudafed.

Tigerfan53
Veteran Member


Date Joined Jan 2011
Total Posts : 790
   Posted 6/6/2012 9:50 PM (GMT -6)   
As long as you are below penetration hardness you are ok.

I am being treated at Sloan Kettering and my instructions say take 4 - 30mg plain Sudafed tablets if you are still at penetration hardness at 2 hours.

shipper12
Regular Member


Date Joined Mar 2012
Total Posts : 110
   Posted 6/7/2012 10:15 AM (GMT -6)   
Tiger
 
You right it IS 2 hours In the Sloan Kettering instr. After 3 hours you supposed to call the hot line. Luckily, I hardly ever go over 2hours. When I do, I take th Sudafed which seems to work fast.
 
I hear cold compresses also works. Have you tried that?
 
This may seem silly, but what is penetration hardness? I ssume its being able to have intercourse. Before I told trimix i get  almost hard enough

sfhotrod
New Member


Date Joined Apr 2012
Total Posts : 11
   Posted 6/7/2012 6:38 PM (GMT -6)   
I have been using it for about a year and I finally settled on .18 as the dose for me. I do find that I occasionally miss the right angle and have gotten it into the urethra and then nothing happens.....after 10 minutes i do it again and then its fine. I also becareful I don't get it into one the larger veins because the same thing happens. I also alternate between left and right sides.

Now that I have had to start lupron therapy my urologist suggest a slightly higher dose. I went up to .22 and that did the trick.

JStars
Regular Member


Date Joined Oct 2005
Total Posts : 451
   Posted 6/7/2012 10:36 PM (GMT -6)   
Ship,

Penetration hardness? Just call it rock hard or achingly hard, or no bend hard. That would be the type you might worry about if it was still around going on 3 hours. If it is bendable (in the middle of penis) and even a little squeezable then that is probably nothing to worry about. I've never taken sudafed even once .. although a couple times I did down a vodka or two to help things. Dunno if that helps, but it would sure make you be more relaxed if you did have to go to the ER (just let someone else drive!).

J

StrictlyInc
Regular Member


Date Joined Dec 2006
Total Posts : 331
   Posted 6/7/2012 10:59 PM (GMT -6)   
@sfhotrod: so if the first injection doesn't work (e.g., your injection into the urethra) you inject again? I thought this was a no-no... though I have done it myself, switching to the other side.

also, how do you know when you have injected into the urethra?
____________________

Prostate cancer diagnosed: May 15, 2006 (age 40)
Gleason score: pre-surgery 3+3=6; post-surgery 3+4=7
daVinci radical prostatectomy: July 25, 2006
size of tumor: approx 1.1 inches; negative margins from surgery

- number of pads/day at 3 months after surgery: 3 to 5
- number of pads/day at 4 months after surgery: 1 to 2
- number of pads/day at 6-18 months after surgery: 0 to

Im_Patient
Veteran Member


Date Joined Aug 2009
Total Posts : 523
   Posted 6/7/2012 11:48 PM (GMT -6)   
StrictlyInc - I think you have your terminology mixed up.
You NEVER want to inject into the urethra - that is the small tube that the pee goes through near the bottom of the penis. Since you had a prostatectomy, you have had a catheter - it goes into the urethra. There are 2 "tubes", one on each side of the penis, that swell with fluid when an erection occurs. They are called corpus cavernosum. You want to inject into one of those via the side. The bimix, trimix, or caverject are chemicals that get the swelling to occur.

I only ever injected a single time per episode, but if you did not inject enough with the first injection, as long as you don't inject more than is needed with the second (and you immediately re-inject at a different location), I would not think there should be a bad consequence.
Jeff

StrictlyInc
Regular Member


Date Joined Dec 2006
Total Posts : 331
   Posted 6/8/2012 2:03 AM (GMT -6)   
@Im_Patient: thanks for the explanation, but I know what the urethra is, and I know I don't want to inject into it. I asked the question about the urethra to sfhotrod because he seems to know when he has hit the urethra. so I was just curious as to how he could notice such a thing. I know when I hit fairly large veins, but don't know how one would even know they hit the urethra, other than maybe bleeding during urination.
____________________

Prostate cancer diagnosed: May 15, 2006 (age 40)
Gleason score: pre-surgery 3+3=6; post-surgery 3+4=7
daVinci radical prostatectomy: July 25, 2006
size of tumor: approx 1.1 inches; negative margins from surgery

- number of pads/day at 3 months after surgery: 3 to 5
- number of pads/day at 4 months after surgery: 1 to 2
- number of pads/day at 6-18 months after surgery: 0 to

Im_Patient
Veteran Member


Date Joined Aug 2009
Total Posts : 523
   Posted 6/8/2012 2:28 PM (GMT -6)   
Strictly, thanks for clarifying your post. Now I understand your perspective.

There was a post in the last month or two of someone who hit the urethra while injecting, and had blood leak out the end, and also did not receive an erection. I think those two symptoms would give you the indication.
Gleason,3+4;PSA 9.8,Nerve-sparing RRP,03/2008(Age 48 then),pT2c, 60g, neg margins; perineural & lymphatic invasion;3 lymph nodes removed,clear; seminal vesicle invasion:absent;Gleason 4 was 5-10%; PSA <0.1 until Oct 09:0.1; retest <0.1; scans clear;monthly results from Jan 2010:0.2,.2,.17,.17,.24,.31,.29,.41, IGRT SRT started 8/4/2010, PSA@5 weeks in: .17,after:.12,.10,.06, .05 since

buckskin544
New Member


Date Joined Jun 2012
Total Posts : 3
   Posted 6/18/2012 7:11 PM (GMT -6)   
I have been taking trimix off and on for about 12 or more years.  Lost track to be honest.  I stopped taking it for awhile and tried all the oral tabs but to no avail, so eventually went back to trimix.  It works ok but have been having quite a time figuring out the proper dose.  .5 of a cc seemed to be about right but it didn't stay hard for very long.  Nothing like is being described here.   I injected today and had a lot of blood come out of my urethra and never even got an erection out of it.  I did wind up with a big lump on the tip of my penis howeverand it has changed color big time.  I called my urologist on this and he said not to worry but didn't say what had caused this. Any thoughts anyone may have is much appreciated.

142
Forum Moderator


Date Joined Jan 2010
Total Posts : 5846
   Posted 6/18/2012 10:01 PM (GMT -6)   
Buckskin,
Welcome to HW. We like to have you introduce yourself with your basic Prostate Cancer journey to date.
 
"I injected today and had a lot of blood come out of my urethra and never even got an erection out of it. "
 
Sounds like you hit the urethra, and injected into it. That could cause the bleeding, and the lack of reaction. You'll likely have some burning the next few days.
Moderator - Prostate Cancer
(Not a medical professional)

DaVinci 10/2009
My adjuvant IGRT journey (2010) -
www.healingwell.com/community/default.aspx?f=35&m=1756808

buckskin544
New Member


Date Joined Jun 2012
Total Posts : 3
   Posted 6/19/2012 6:44 AM (GMT -6)   
I think I may have logged into the wrong part of the site by accident.  I do not have cancer as far as I know.  I suffer from erectile dysfunction.  I do appreciate the response on my question however.

142
Forum Moderator


Date Joined Jan 2010
Total Posts : 5846
   Posted 6/19/2012 9:34 AM (GMT -6)   
Buckskin,
 
No problem. We do discuss ED to some extent because it is a very real side effect of Prostate Cancer treatment. ED does not have it's own "home" on Healing Well, and we do have to keep it toned down, because this is a site open to men, women, and children 13 or over who suffer from quite a number of problems. Once a member signs up, they can visit any forum.
 
For ED questions, I would suggest you try a site managed by folks we know here - www.franktalk.org. Because that is an "18 and over" site, the conversation can be a little more complete.
 
I'll also add my wish that you don't have to come back here because of Prostate Cancer. Get your PSA checked just in case.
Moderator - Prostate Cancer
(Not a medical professional)

DaVinci 10/2009
My adjuvant IGRT journey (2010) -
www.healingwell.com/community/default.aspx?f=35&m=1756808

buckskin544
New Member


Date Joined Jun 2012
Total Posts : 3
   Posted 6/19/2012 12:35 PM (GMT -6)   
Thank you, I already did that.  Waiting on reply from the doc as we speak.  Thank you for good wishes.
New Topic Post Reply Printable Version
Forum Information
Currently it is Wednesday, August 27, 2014 3:55 PM (GMT -6)
There are a total of 2,202,410 posts in 245,155 threads.
View Active Threads


Who's Online
This forum has 155103 registered members. Please welcome our newest member, Jephrey74.
461 Guest(s), 22 Registered Member(s) are currently online.  Details
Jacksmum, Colita, Roxie60, I got uc, Serenity Now, AZ9999, Merrida, letthepeoplesing, getting by, cilly, AML94, Dubaideb, Techman101, lesweet1971, gtothep82, Dr-A, AubreyBear, Traveler, quincy17, Myself 09, _Marine_, iPoop


Follow HealingWell.com on Facebook  Follow HealingWell.com on Twitter  Follow HealingWell.com on Pinterest  Follow HealingWell.com on YouTube
Advertisement
Advertisement

©1996-2014 HealingWell.com LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer