How much does sex before a blood test affect PSA?

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Gleason 6
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Date Joined Mar 2011
Total Posts : 790
   Posted 6/27/2012 7:42 AM (GMT -6)   
Funny thing. On Monday I remembered that I had an appointment with my urologist on Friday for a 10 month post seed checkup. So, I rushed in and had a PSA blood test hoping that the doctor would get the results by Friday. I forgot that I had sex the night before (this is the second time I have done this!). Rushing in to get the test was all in vain as I ended up cancelling the appointment because I found out my wife (at my request) had changed it to Thursday. I have a yearly coming up with my radiologist, so I think I will just wait until I see him and skip the urologist for now (unless the blood test is shockingly up). They both will just look at the PSA and do a DRE.

Any ideas or data on how sex the night before a test affects the PSA results?
Click here for My Journey from diagnosis to decision to have seeds
Age 61
PSA 4.3 9/10
PSA 6.73 5/18/11
Template Biopsy GS6(3+3)
Stage T1C
CT neg
8/5/11 87 I-125 seeds.
PSA 6 months after seeds 3.9 - 2/16/12
PSA 9 months after - 3.2 5/2/12

Steve n Dallas
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Date Joined Mar 2008
Total Posts : 3959
   Posted 6/27/2012 8:20 AM (GMT -6)   
Many people suggest not having sex for about 48 hours before a blood draw... I on the other hand am not crazy about trying to influence test results. It is what it is...

Water Guy
Veteran Member


Date Joined Jul 2011
Total Posts : 2403
   Posted 6/27/2012 8:27 AM (GMT -6)   
The on going opinion is that sex and ejaculations before the blood draw can cause the prostate to produce more PSA. However the question should be, after having RT or seeds and since the radiation pretty much kills off most of the prostate tissue, does sex or ejaculation have any effect on the PSA it produces?
 
Terry
AGE 61 Dx with fam hist of PC
PSA
1.5 5/09
2.5 6/10
3.5 12/10 ref URO
5.25 2/11 DRE Neg
BX 4/13/11 2 of 12 cores diag both sides 15% & 20% GS7(3+4)
RALP nerve-sparing 6/8/11 path G7 pT2C, Marg-Lymph-Sem-Vas-PNI- organ confined 60% tumor involved 69grms 4.3X4X3 cm
100% dry 7/3/11
post PSA
8//11 <0.07
12/11 <0.04
3/12 <0.01
6/11/12 <0.01
TRIMIX therapy for ED seeing improvement

overthepond
Veteran Member


Date Joined Apr 2011
Total Posts : 599
   Posted 6/27/2012 10:25 AM (GMT -6)   
I don’t have any answers – we’ve ‘abstained’ the 72 hours for each previous test so we are just trying to keep a level playing field this time too. A recent post suggested we should be abstaining from alcohol too for the 72 hours but no chance of that with Euro 2012 footie match tonight and Jeff’s test tomorrow!
Dont’ understand why you would cancel your urologist check-up though?
Husband's age 63
Excellent health
First PSA test - 7
Two months later - 11
Biopsy results: Gleason 3+3 in two cores (right medial 30% and right apex 90%). Small benign-feeling prostate
Feb 2011 – Brachytherapy – Iodine 125
PSA results: Dec 2010 - 11, May 2011 - 3.83, Aug 2011 - 3.18, Nov 2011 – 1.78, Feb 2012 - 2.77

142
Forum Moderator


Date Joined Jan 2010
Total Posts : 5809
   Posted 6/27/2012 12:11 PM (GMT -6)   
Johns Hopkins, in the mass of newsletters they put out, say no sex the day before.
 
Terry's point is also valid. If the poor guy has been nuked to death, would it matter? Good question, no answer forthcoming from me.
Moderator - Prostate Cancer
(Not a medical professional)

DaVinci 10/2009
My adjuvant IGRT journey (2010) -
www.healingwell.com/community/default.aspx?f=35&m=1756808

Gleason 6
Veteran Member


Date Joined Mar 2011
Total Posts : 790
   Posted 6/27/2012 12:20 PM (GMT -6)   
Over,

Basically, I'm cheap and will be seeing the Radiologist in a month for my 1 year checkup. It doesn't seem like the Uro does much more than look at the PSA and do a DRE...same as the Radiologist will do. If the PSA is high or going up, I'll make the appointment.

Good luck with your appointment and PSA reading.

England lost a tough one against Italy. What a game.
Click here for My Journey from diagnosis to decision to have seeds
Age 61
PSA 4.3 9/10
PSA 6.73 5/18/11
Template Biopsy GS6(3+3)
Stage T1C
CT neg
8/5/11 87 I-125 seeds.
PSA 6 months after seeds 3.9 - 2/16/12
PSA 9 months after - 3.2 5/2/12

Arkyrider
New Member


Date Joined Apr 2012
Total Posts : 4
   Posted 6/27/2012 1:28 PM (GMT -6)   
G6, If your looking for a specific #or% increase due to having sex before a psa test. You probably won't find one, I never could find one (after a couple of hrs. of internet searching) just the general response your getting in this thread. I drank beer and had sex the night before along with riding my motorcycle to the GP's office for a routine checkup (long over due) the GP also did the DRE before the blood draw for a psa test (my first psa test,age55). All 4 things I just mentioned have the potential to raise the psa (which came back at 13)Which got me a trip to the URO . I asked him the same thing your asking in this thread. My question to him was, what your asking. His short answer was all 4 activities together wouldn't raise it from 1 or 2 to 13. That was back in mid March Had the LDR seed implants June 4th.

leeanglo
Regular Member


Date Joined Dec 2010
Total Posts : 191
   Posted 6/27/2012 1:35 PM (GMT -6)   
I heard sex 48 previous or rigourous cycling can raise PSA by a max 10%
psa on dx 144, gleason 4+3 7 12 biopsie cores cancerous
T3a N2 M1.
psa after 3 months zoladex 20
T levels 0.5 after 3 months zoladex.
now taking 50mg cosadex daily also.

Gleason 6
Veteran Member


Date Joined Mar 2011
Total Posts : 790
   Posted 6/27/2012 1:36 PM (GMT -6)   
Arkyrider,

Thanks for the info and welcome.

You had seeds June 4th of this year? I hope you are doing well. You may want to add your stats to your signature.

Best of luck to you.
Click here for My Journey from diagnosis to decision to have seeds
Age 61
PSA 4.3 9/10
PSA 6.73 5/18/11
Template Biopsy GS6(3+3)
Stage T1C
CT neg
8/5/11 87 I-125 seeds.
PSA 6 months after seeds 3.9 - 2/16/12
PSA 9 months after - 3.2 5/2/12

Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3220
   Posted 6/27/2012 1:51 PM (GMT -6)   
I want consistent, comparable PSA results so I control all the factors within my power: when I take the test, what I eat before it, which lab I use, and sex. Since it is much easier for me to have no sex, cry , I wait 72 hours minimum.

about a year ago I recall seeing a legitimate study on the effect I'm sure someone will find it here. The results were quite significant - for guys with prostates.
Jeff

Arkyrider
New Member


Date Joined Apr 2012
Total Posts : 4
   Posted 6/27/2012 1:51 PM (GMT -6)   
Yes G6, 6/4/2012. I'll fill out my stats here shortly.

clocknut
Veteran Member


Date Joined Sep 2010
Total Posts : 2262
   Posted 6/27/2012 2:10 PM (GMT -6)   
A very interesting question.  Unfortunately, I don't remember what "sex" is.

Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3220
   Posted 6/27/2012 2:18 PM (GMT -6)   
Wow I just googled "effect of ejaculation before prostate specific antigen PSA test 24 hours 48 hours 72 hours" There were lots of studies! It is significantl

One Greek paper from Dept of Internal Medicne , Naval Hospital of Crete, Chania, Greece,
"We have examined a 52-year-old asymptomatic Greek subject who in an annual routine blood test had a serum total PSA of 6 ng/ml. His personal and family medical history was unremarkable. There was no history of using drugs, or having symptoms of benign prostate hypertrophy, prostate cancer or prostatitis, and he had no recent diagnostic clinical tests of the genitourinary tract. The patient refused digital rectal examination. An abdominal and prostate ultrasound scan showed no evidence of benign prostate hyperplasia or of prostate cancer. Serum total PSA after ten days was 5.2 ng/ml, but the percent free PSA was 27% (normal > 20%) [8]. After a month, serum total PSA value was 1.2 ng/ml. In another blood test after 3 months, serum total PSA value rose to 7 ng/ml with a percent free PSA of 40%. The urologist recommended a transrectal ultrasound-guided prostate biopsy. The patient refused biopsy. All serum PSA measurements were performed with the same radio-immune assay (RIA) in a nuclear medicine laboratory (Tandem-R PSA, Hybritech Inc., USA) with normal range 0-4.0 ng/ml. The percent free serum PSA was calculated as the ratio of serum free PSA to total PSA multiplied by 100. After discussing this situation with the patient, we were informed that he had sexual activity and ejaculation in less than 24 hours before the first and before the last serum PSA measurements (being 6 and 7 ng/ml respectively). Ejaculation might have had an effect on serum PSA levels in our patient. All other values of serum total PSA measurements performed at least 4 days after sexual abstinence were <1.2 ng/ml..

That's an extreme case. The guy ejaculated within 24 hours of test and had a PSA of 6. One month later it was 1.2. At 3 months he repeated the test after ejaculating within 24 hours and his PSA was 7!
Very significant.
I'd live to be a fly on the wall in that bedroom!
Age: 59, Mar 36 yrs, 56 dx, PSA: 4/09 17.8, 6/09 23.2
Biopsy: 6/09 7 of 12 Pos, 20-70%, Gleason 4+3 Bone, CT Neg
DaVinci RP: 7/09, U of Roch Med Ctr
Path Rpt: Glsn 3+4, pT3aNOMx, 56g, Tumor 2.5x1.8 cm both lobes and apex
EPE present, PNI extensive, Sem Ves, Vas def clear, Lymph 0/13
Incont: 200ml/day ED: Trimix
Post Surg PSA: 10/09 .04, 7/10 <0.01, 7/11 <0.01, 1/12 <0.02
AdV Sling 1/10/11 Dry

Gleason 6
Veteran Member


Date Joined Mar 2011
Total Posts : 790
   Posted 6/27/2012 2:41 PM (GMT -6)   
I wish I would have thought of abstaining! At least I would not question the results. Maybe I'll call tomorrow and see if they got the results.
Click here for My Journey from diagnosis to decision to have seeds
Age 61
PSA 4.3 9/10
PSA 6.73 5/18/11
Template Biopsy GS6(3+3)
Stage T1C
CT neg
8/5/11 87 I-125 seeds.
PSA 6 months after seeds 3.9 - 2/16/12
PSA 9 months after - 3.2 5/2/12

Steve n Dallas
Veteran Member


Date Joined Mar 2008
Total Posts : 3959
   Posted 6/27/2012 2:54 PM (GMT -6)   
Are you going to abstain from orgasm the rest of your life? The words "false positive" comes to my mind when I think about doing things that might influence test results.

Neither of my two Uro's or my GP ever said anything about anything except when and where to get blood drawn.

How about all the other times you've had blood drawn? If they happened shortly after having the big O - then you're on the same track.

Worried Guy
Veteran Member


Date Joined Jul 2009
Total Posts : 3220
   Posted 6/27/2012 5:38 PM (GMT -6)   
If you want consistency, be consistent.

Steve, We don't have to abstain for the rest of our lives. We just have to do our part and remove variables we can control.

I always get my test done in the morning before I have eaten breakfast. Does that make a difference? Absolutely Why? Because in my mind I have eliminated that variable. It might not make a difference in the actual PSA number. But it sure makes a difference in my head.

There is tons of evidence that ejaculation, DRE, and even bike riding affects PSA. (You can do a quick google search and you'll see it.) Abstaining for 48 or 72 hours or is a small price to pay for the confidence that your numbers are not affected by those variables.

Supposedly the PSA test for those of us without prostates is not affected by the big O, but, I still abstain to remain consistent.

Jeff

James C.
Veteran Member


Date Joined Aug 2007
Total Posts : 4450
   Posted 6/27/2012 6:51 PM (GMT -6)   
HWell, if my doc says to fast 12 hrs before getting a blood test for cholrestol, glucose and such , I,m gonna do it. I don,t think that is cheating the test or giving false data. Same with the pas test, the doc says no, so I don,t. What,s the difference between these two tests?

Post Edited (James C.) : 6/27/2012 5:55:31 PM (GMT-6)

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