How long for Synthroid to start working?

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Tirzah
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Date Joined Jul 2008
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   Posted 6/15/2009 8:46 PM (GMT -6)   
Hi all!
I was recently diagnosed with hypothyroidism & just started Synthroid last week. Does anyone know how long until I start feeling better? I have been feeling so run down for a long time. When my hair started falling out I got tested for TSH & it came back high. My dermatologist says it will be probably 6 months for my hair to start growing back, but I'm wondering how long until the other symptoms start to subside.

Also, I have a stomach problem (infection, probably an ulcer also we're waiting on test results) so I have been losing a LOT of weight. I've heard that hypothyroidism usually causes weight gain so I'm wondering whether Synthroid would end up causing weight loss. I'm a little concerned since I've already lost so much weight. I see my PCP again in 3 weeks, but I'm hoping maybe some other members can share their experiences so maybe I don't have to worry so much in the meantime.

Thanks much!
Frances
Moderator -- Depression Forum


Tavish
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Date Joined Jul 2003
Total Posts : 2272
   Posted 6/15/2009 9:18 PM (GMT -6)   
My experience is that I was able to feel some improvement on each med dose increase but the total max benefit takes up to 6 weeks.
My colleague had one lobe removed and after a month felt very run down. They put her on 50 mcg of synthroid and within a few days she felt much better.
I was hypo for a few months following surgery, and had IBS type symptoms for the entire time. A large dinner or certain foods sent me running for a restroom and I was sure I had IBS....they said stomach problems are related to being hyper and not hypo.
Well my symptoms started a week after going off meds and got better one week after my dose went from 112 to 150. Stomach has been fine since... so my point is that your stomach problems may be from being hypo, even though it is more commonly related to being hyper.
Good luck!
Lori


gachrons
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Date Joined Mar 2007
Total Posts : 4527
   Posted 6/15/2009 9:22 PM (GMT -6)   
Hi I have crohn's disease and see that immune system play an important role with thyroid problems as well. Sorry I cain't help you much with your question but just wanted to give some support as a person living with crohn's I am amazed at how many problems the immune system can cause.I do know someone that takes a replacement med because they have had their thyroid removed .Hope someone comes along with some answers. lol gail
Hallarious woman over 50 ,CD ,IBS 27 years--resection,fistula's,obstructions,hemmies,and still alive.lol gail
"Blessed are those that can give without remembering and recieve without forgetting ~Aurthor Unknown~Blessed are they that have the joy of helping others~ Moderator gail


Tirzah
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Date Joined Jul 2008
Total Posts : 2137
   Posted 6/15/2009 9:34 PM (GMT -6)   
Gail,
Thanks for your support.

Lori,
That is so encouraging to hear that your stomach problems went away with the Synthroid. I was hoping they were related. I can hardly believe how many of my symptoms are related to my thyroid problems. I am already feeling a bit more energy & less depressed even though I just started the meds last week. My PCP thinks that my stomach probs & anemia are signs of an ulcer & are not related to my thyroid, but I have been anemic or borderline anemic most of my life & have been tested for ulcers & never had one yet. The weight loss & nausea started about the same time as the rest of my symptoms, so I'll keep my fingers crossed that maybe it's all due to my thyroid. Thanks so much for sharing with me. :)

Frances
Moderator -- Depression Forum


saposs
Regular Member


Date Joined Nov 2008
Total Posts : 339
   Posted 6/15/2009 9:34 PM (GMT -6)   
It takes about a 6 weeks for med to work. Last time my TSH went high despite taking medicine, my major symptom was - severe leg pain during evening walk- ....with higher dose it took a few weeks to get better.
UC forum : Right now -FLARING (after my Rubella vaccination)
Diagnosed in Jan'2009: Canasa suppositories 1000 nightly - worked for 2 months then re-flare
13 may: canasa 1000 X2 daily for 2 weeks - to start Lialda after 2 weeks if canasa double dose does not work
Lialda X2 started on 30th may.
Symptoms: Mucus, blood, constipated (not always), Lots Gas
Also started Probiotic from 23 Mar & fresh Turmeric root from 25 March'09- stopped both on 10th May

Thyroid Forum: Dx in Dec'08, levothyroxine from 50mcg to 77 mcg in June'09 :-(


Tirzah
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Date Joined Jul 2008
Total Posts : 2137
   Posted 6/15/2009 10:20 PM (GMT -6)   
Thanks saposs,
I had been in increasing pain & saw my pain specialist for injections which didn't help much. I have noticed that my knee pain is reduced quite a bit now & my back pain is a tiny bit better, so I'm hoping that the pain will continue to decrease over time. It is so encouraging to read all these stories about people being helped so much by starting on thyroid meds. Thanks so much for the encouragement.

Frances
Moderator -- Depression Forum


lambkins
Veteran Member


Date Joined May 2008
Total Posts : 563
   Posted 6/16/2009 11:29 AM (GMT -6)   
Hi i have hypothyroidism and ulcerative colitis and for the last week have been getting really bad leg pains which i put down to finishing prednisone but seem to blame that for everything lately i take 50mg of levothyroxine for thyroid maybe dose needs changing did not even think it could be to do with my thyroid for years i have just taken the tablets and not thought any more have bloods done and thats about it.
  
  Diagnosed 22.5.08 with Lft sided U/C
  Meds Predfoam 20mg 2x day stopped started pentasa supps 1gm 26/6/08
 Asacol 800mg x2 twice daily
  Domperidone 10mg as needed
  co codamol 30/500 x2 when needed
  Asacol foam 2g nightly 19/3/09
  Prednisone 60mg 19/3/09 tappering after2wks


opnwhl4
Forum Moderator


Date Joined Dec 2008
Total Posts : 4721
   Posted 6/17/2009 2:51 AM (GMT -6)   
Frances -
My wife was diagnosed with Hashimotos at 13. She has had the left side removed and the right side basically cut in half(thickness). Before the surgery she was losing a lot of weight even with being hypo. Since the surgery she has struggled with her weight and has not been able to get the symptoms to subside. She still deals with the tiredness, inability to handle cold temps, some hair lose at times, leg pains, etc. Her surgery was in 2003 and her levels are constantly changing. She has to be tested every 6 months to stay on top of it. And unfortunately her remaining thyroid is starting to enlarge again, as they said in might. The Ents and Endos told her the symptoms should subside in a couple months at first, now they say they may never change.
It's strange that even though it was enlarged and she had nodules, that were benign, she felt better before they did the surgery than she does now. And now they say they should have just removed both sides and the synthroid would probably have worked better. Some day I am sure she will have had enough and decide to have the rest removed, but she doesn't want to seal with the surgery again just yet.
I pray everyone dealing with this finds a way to manage their symptoms. I have seen how frustrated you can be and wish you all can be symptom free.
I am a regular on the GERD forum and have told her about this forum starting, but she just isn't comfortable yet to come her.
Sorry I ended up rambling here instead of giving Frances a straight answer.
Take care,
Bill

MMMNAVY
Veteran Member


Date Joined Jul 2006
Total Posts : 6923
   Posted 6/17/2009 12:23 PM (GMT -6)   
No worries Bill. Ramble all you want!


I have heard of people having results in a couple days, but for me it took about 2 months.
Forum Co-moderator - Crohn's Disease:_All comments have the caveat contact your local health care provider.

I will find a way or make one. –Phillip Sidney 1554-1586

All that I am and all that I shall ever be, I owe to my Angel Mother.

The Bucket List- Have you found joy in your life?  Has your life brought joy to others?

Make sure your suffering has meaning…


jeanneac
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Date Joined Feb 2009
Total Posts : 1611
   Posted 6/17/2009 4:04 PM (GMT -6)   
Gosh, looks like a few of us from the UC forum also have thyroid issues-:) I guess no suprirse since they are both autoimmune diseases.
diagnosed 1/09 with colitis & diverticulitis
 54 yo, colazal, fish oil, synthroid, cymbalta
good results w/ acupuncture


Tirzah
Veteran Member


Date Joined Jul 2008
Total Posts : 2137
   Posted 6/17/2009 6:08 PM (GMT -6)   
Bill,
Thanks so much for the info & story. It really is so helpful to me to keep hearing about other people's experiences. That's awful about your wife feeling worse after surgery. Fortunately, I don't seem to have any lumps right now & I'm hoping it will stay that way. But I just feel so sick. I tried my PCP again today & she has yet to get back to me about my latest test results.

All,
This is really great all the information everyone has to share. I have been reading some about hypothyroidism, but it seems like sites either list only a few symptoms, or they list basically every sickness known to man. I'm trying to sort out what is what & to see when the Synthroid might help and if I might need a higher dose at some point (I'm at 50 right now). It is so great to read about everyone's experiences.

Many thanks,
Frances
Moderator -- Depression Forum


MMMNAVY
Veteran Member


Date Joined Jul 2006
Total Posts : 6923
   Posted 6/19/2009 6:51 AM (GMT -6)   
Frances, have you done a pill camera?
Forum Co-moderator - Crohn's Disease:_All comments have the caveat contact your local health care provider.

I will find a way or make one. –Phillip Sidney 1554-1586

All that I am and all that I shall ever be, I owe to my Angel Mother.

The Bucket List- Have you found joy in your life?  Has your life brought joy to others?

Make sure your suffering has meaning…


Tirzah
Veteran Member


Date Joined Jul 2008
Total Posts : 2137
   Posted 6/19/2009 8:33 PM (GMT -6)   
I haven't. I'm interested in them (though trying to find it is a bit disturbing), but I've been told that they won't do the camera pill until after they have already done an upper & lower endoscopy. I'm not sure why that is -- I kinda panicked when I heard the word "endoscopy". I had a really horrible experience the last time -- long story short, the GI violated the contract I signed, overdosed me on anesthesia (I didn't know where I was for 3 days) & then lied to me and told me I had Barrett's Syndrome to cover up the fact that he had badly scraped my esophagus with the scope & needed to put me on pills so everything could heal up. A friend of the family, one of the top GI specialists in the US, ended up reviewing my case & helping me get things straightened out, but it was all really horrible & the fact that he lied to me & told me I was pre-cancerous at age 19, was really upsetting.

So I'm hoping they can figure out some sort of treatment plan with just blood work. If they can figure out a way to do the pill cam & get my insurance to cover it, I suppose I would be willing to do that, but I'm just really concerned about getting more sedation for a procedure. I know you can get endoscopies done without sedation, but that was what my last one was supposed to be -- I even signed a statement & wrote on there that they couldn't give me demerol, but they gave it to me anyways. It was a mess & I'm worried it would happen again. So I guess we'll just have to see whether the Synthroid will be enough & if not, take it from there.

Thanks for your ideas!

Frances
Moderator -- Depression Forum


atlcdn
New Member


Date Joined Dec 2012
Total Posts : 1
   Posted 12/23/2012 10:32 PM (GMT -6)   
I just recently went from 75 mcg to 137 mcg and I am not nearly as tired as I usually am. [about a week on the higher dose]..... I could fall asleep anywhere, anytime. I believe I will be feeling much better in the next few weeks. Also, this is important...make sure you take Synthroid and NOT the generic. My doctor insists on that and I have done some research..the generic does not work nearly as well and can cause some problems. I wish I could remember what...sorry... :) [My dr is a complentary medical dr...I think most conventional drs will tell you this isn't true]

MA10
Regular Member


Date Joined Oct 2012
Total Posts : 115
   Posted 1/2/2013 11:08 PM (GMT -6)   
You are not alone. Several of us have to put up with the daunting troubles of thyroid disorders. I am like you: I didn't realize how much your thyroid could affect EVERY other part of your body. It's crazy. But, thankfully we live in a day and age where medicine can greatly reduce the symptoms.

I went undiagnosed for about a year or so, and got my full plate of every hypo symptom. Now, though on Synthroid I still am working through it all. Just keep hanging to the fact that one day it will be better. I have come a LONG way from a year ago and just keep fighting, thus becoming stronger everyday.

Thank you all for sharing your stories. It always tends to offer encouragement to those of us going through similar things. Take care and "May the FORCE be with you". haha.
Depression, Generalized Anxiety Disorder, Osteoarthritis in ankle/foot and knee, Chondromalacia patella, Accessory Navicular Syndrome, Hamstring tendonitis, Hypothyroidism

#LGLP, #JN3:16 #PS28:7 #ask_me_about_THEHOPE_i_have

jen2011
New Member


Date Joined Apr 2012
Total Posts : 2
   Posted 6/30/2013 9:49 PM (GMT -6)   
From 5/2011 to 11/2012 I had 15 deep tissue treatments of glucocorticoids with intermittent prescriptions of prednisone. This was to treat inflammation from a brain & spine injury, the worst area being around my brain stem because of the lack of support from my now herniated C1-C7 discs & severe lardosis.
Anyway, according to my endocrinologist as a result of the treatment I now have thyroid disease (note: because I had hyperthyroidism as a young adult I've had continuous TSH screens over the years; it never exceed 1.18 until now where my value is over 8). After having the same weight (+/- 5 lbs) for more than 15 yrs I put on more than 50 pounds in a 3-month period. I'm sure I've even gained more but I stopped finding out how because I was too injured to exercise to do anything about it (I was also in the hospital much of the time; I also have problems with my lumbar area from a birth defect but that's another story).
I started synthroid (50 mcg) a week ago & I am praying that this will help me eventually regain a normal functioning thyroid. I've seen some really positive, but of course the negative ones scared the heck out of me (I felt bad for those who wrote them too). Even though I'm down to 500 calories a day (I have been for months now out of desperation) I feel like I look even more bloated since I started taking synthroid. I have read reviews where people gained weight. Again, I'm praying that this is just an initial side effect. Even though I've had non-stop throat pain w/hoarseness, dermatological issues, fevers, & weakness before taking the medicine my doctor said I might feel worse at first before I feel better & this seems to be the case. Also, as a migraine sufferer my doctor said this too could worsen initially, which it has, but I'm cautiously optimistic that this likelihood is lessening as my body seems to be getting used to synthroid.
Anyway, I wondering if any of what I'm going through is relatable & is there any hope of a light at the end of this tunnel? Thank you for reading & any help would be greatly appreciated.
(I apologize for the lengthiness of my post...I'm feeling pretty sick as I'm writing this)

Post Edited (jen2011) : 6/30/2013 9:52:50 PM (GMT-6)


Judy2
Forum Moderator


Date Joined Mar 2003
Total Posts : 8918
   Posted 7/1/2013 12:26 PM (GMT -6)   
It takes approximately six weeks for synthroid to take full effect, doubt there would be any detectable changes at all after only a week. At this point there's not much you can do except try to relax as much as possible and wait it out.

I've have very good luck with synthroid, as do most hypothyroid people. We have a lot here who don't do well on synthroid because people who have a more difficult course with any treatment are much more likely to seek the support of a group such as this. Hopefully you will do well also. Remember also that your levels can change gradually and your meds may need to be adjusted over time. It can take a couple of years to get to your maintenance level, but generally after the first month or so you'll feel better.
Ulcerative colitis diagnosed in 2001; symptoms as early as 1992. In remission since 2006 with Remicade.
Inflammatory osteoarthritis; osteonecrosis from steroids
Grave's disease successfully treated with radioactive iodine and now on Levothyroxine.
Type II diabetes induced by steroids.
Meds: Remicade, Colazal, Levothyroxine, Mobic, Metformin

Moderator, thyroid forum

jen2011
New Member


Date Joined Apr 2012
Total Posts : 2
   Posted 7/2/2013 9:08 PM (GMT -6)   
Judy2:

Thank you so much for your help. I have people who depend on me (like many others on here) & don't have anybody close to my age (I'm the sole supporter to my elderly parents & child; again, I know I'm not alone) so no one to talk about anything health-related in person.

I've read about how adjusting one's dose is key & when I see my endocrinologist in 3 wks I'm sure we'll discuss this as she increases my dosage. I have a feeling for now that she just wanted to make sure my body handled synthroid. Right now there are 11 nodules that she's concerned where some might have to be surgically removed...had bloodwork this week to confirm/dis-affirm what was shown on the ultrasound... & for other reasons I'm having a hysterectomy along with an oophorectomy within the month, so I don't if I can resume the synthroid during these operations. She (my endocrinologist) & my ob/gyn think the hysterectomy & oophorectomy might significantly help my thyroid function. So either way, I have hope my thyroid will eventually get better. (I've only had medicine for a week but it's been a major problem for 8 mos. now.)

Anyway, your response is a great support to me. I know I got to be patient with feeling better. I'm glad there's a online support forum...just wish this disease didn't exist for anyone! Hope all is well for anyone on this site :-)

Jenna

Post Edited (jen2011) : 7/2/2013 9:20:50 PM (GMT-6)


kim123
Veteran Member


Date Joined Jul 2006
Total Posts : 1182
   Posted 7/3/2013 10:02 PM (GMT -6)   
Are any of you on natural dessicated thyroid hormone, or have ever tried it? I read a lot of positive stories for those who dont find great success with synthetic hormones?....even those with Hashi's.

Judy2
Forum Moderator


Date Joined Mar 2003
Total Posts : 8918
   Posted 7/4/2013 7:04 AM (GMT -6)   
Kim, we do have a number of people with Hashi's who post here and are on Armour dessicated hormone. You may want to start your own thread with a title about what you want to discuss as that will surely get more responses.

Since this is a holiday week traffic may be light, so please be patient with us.
Ulcerative colitis diagnosed in 2001; symptoms as early as 1992. In remission since 2006 with Remicade.
Inflammatory osteoarthritis; osteonecrosis from steroids
Grave's disease successfully treated with radioactive iodine and now on Levothyroxine.
Type II diabetes induced by steroids.
Meds: Remicade, Colazal, Levothyroxine, Mobic, Metformin

Moderator, thyroid forum

polekat86
New Member


Date Joined Feb 2014
Total Posts : 2
   Posted 2/28/2014 1:38 AM (GMT -6)   
Wow All of this is a bit new to me. I watched my mom and older brother suffer with hypothyroidism for years. But as they went to have it checked out were told they had a mental illness. Every time they had bad flare ups meds were changed and my mom even received shock treatments. I found out i had it from what i thought was a heart attack. My potassium levels dropped to crisis levels and was told i could die if they couldnt get the levels back up. I have had these symptoms all my life and chocked up to this or that,was called lazy most of my life. I couldnt hold out to do what others could do. My heart goes out to anyone who goes through this because you feel alone. Thoughts that you could be crazy i am sure cross everyone's mind from time to time. Ten medical professionals would of bet a months pay i had heart damage. By gods grace,and prayer warriors no damage nor blockage and i was given the diagnosis of hypothyroidism after many vials of blood drawn,lol

rebounder4ever
New Member


Date Joined Feb 2014
Total Posts : 9
   Posted 2/28/2014 12:00 PM (GMT -6)   
A very close family member of mine was told to have surgery - her FNA's were inconclusive *as were mine when checked for my nodules. Her left lobe was removed. Put on synthroid only. Hashimotos (hypo) She became sicker and sicker. Found to have Epstein Barr virus *old non active mono, or something like that.

Up and down the dosage went. On antibiotics that killed off beneficial bacteria in her gut which caused more problems for her (constipation went for over a week). It was so bad. Then, put on steroids for a twisted ankle. Anti-depressants for anxiety over her husband leaving her while she just signed up for college classes and only had a part time job. She was 900 miles away and alone. Blew up to over 200 pounds.

Came home and I found a great doc for her that found she needed Cytomel as well. Found she is gluten sensitive *thru blood work only - as well as CORN, SOY, Casein, egg whites and GLUTEN. All the stuff that is genetically modified. She has leaky gut.

She felt well after the addition of the Cytomel. And her numbers began to get normalized again.

We went gluten free in foods, home products, personal products and less grains/sugars. NO CORN.

She began losing weight. Began running after classes and would do infraRed saunas. Her eyebrows began to grow back. Then we both went on a bit of Iodine.

That was over four years ago. We continue with organic, gluten free, toxic free home. Our pets are grain free, too.

We are not sure but her really awful doctor insisted she begin the gardacil regimen. She had round 1 and became very ill immediately. My gosh it was awful for her being so far away at that time and alone.

I am trying to talk her into the 23andme dna test. She is positive for the heterozygous a1298c mutation. Brand new. Have no idea of that just yet.

But she graduated with honors (management/finance). Is working for a company she LOVES. Bought her own place and is adamant about health.

Hope this helps? It is awful when you have issues, I know. Best of health to you.

polekat86
New Member


Date Joined Feb 2014
Total Posts : 2
   Posted 2/28/2014 3:42 PM (GMT -6)   
I have been diagnosed with Hypothyroidism. I began noticing a few years back due to the kind of work i did after massaging sore muscles that knots began to form under the skin. Some would have a nerve type burning going on for a bit. Has anyone else noticed this or is it just I?

Cricket0217
New Member


Date Joined Mar 2014
Total Posts : 1
   Posted 3/31/2014 7:58 PM (GMT -6)   
I have been diagnosed with Hypothyroidism. My doctor put me on .75 mcg of synthroid.
I have been taking it for 4 wks. and felt good for about 5 days and now it seems I am feeling
how I was when it all started. Doctor said I should be at 112 mcg of synthroid but wanted to start me slow. I don't understand why. I am tired, moody, depressed, headaches and leg pain.
I just know I am tired of feeling this way and would like to feel normal again.
From everything I have read it doesn't seem that will ever happen.

Any suggestions on what I can do to help improve myself. I'm tired of waiting.

Judy2
Forum Moderator


Date Joined Mar 2003
Total Posts : 8918
   Posted 4/1/2014 6:00 AM (GMT -6)   
It takes about six weeks for synthroid to be effective, so hang in there. Your doctor started you on a low dose to let your body ease slowly into the medication. It's normal thyroid therapy and no doctor should ever start someone on 100 mcg at one time; if the dosage is too high it can throw you into hyperthyroidism, which is much more dangerous than hypo.

Most people with hypothyroidism are treated quite successfully, but it can take some time to get things level and stabilized. Try to think that you're on the road to feeling better, not just that you're still sick.
Thyroid forum moderator

Ulcerative colitis since 2001, starting 8th year of remission with Remicade.
Inflammatory osteoarthritis; osteonecrosis from steroids
Grave's disease treated with radioactive iodine and now on Levothyroxine.
Type II diabetes induced by steroids.
Eczema, darn it!

"It's always something." ~ Rosanne Rosannadanna
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