I also take 4 Lialda a day. I'm currently tapering off of prednisone (I'm almost down to 20 mg). The only side effect I have from the Lialda (or possibly the prednisone) is severe constipation. I also have heartburn and bloating. I told my GI, but she just said I probably have a case of IBS now (she's not the best GI around). She did say to take Colace stool softeners or Miralax, in addition to magnesium suppplements for the constipation. I'm new to UC treatment so I maybe other members have more knowledge about Lialda. I have to say that my meds (prednisone and Lialda) worked immediately. I was symptom free in 7 days and continue be symptom free 6 weeks later. Hope this helps.
EllieKate4 Lialda/day30 mg PrednisoneSCD Diet 2 monthsAssorted probiotics 7/dayAssorted vitamins