celexa and uc?

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bokscarracer
Regular Member


Date Joined Sep 2008
Total Posts : 149
   Posted 10/30/2008 8:44 PM (GMT -6)   
i just started celexa last friday and was a bit worried because i read that it can potentially cause bleeding. i'm currently in a flare and i finally gave in to medications for my anxiety because i really do believe the anxiety is fueling the UC. should i be worried at all? has anybody else here with UC been on any SSRIs? Thanks!

emory
Regular Member


Date Joined Aug 2008
Total Posts : 327
   Posted 10/30/2008 9:52 PM (GMT -6)   
Yes, there are quite a few people on here taking SSRIs, myself among them. (I asked a question similar to yours a couple of months ago, but about Effexor.) My current flare, which led to my diagnosis, actually started a few weeks after I had tapered off Effexor. I started taking it again while flaring, and can't really say whether it's had any effect on the flare itself. Like you, I'm concerned about potential for bleeding, but had to get my insomnia and anxiety under control so I could start feeling better (which I am now).

I wish you the best,
emory
40, female
Dx ulcerative proctitis, 3-5 cm, June 2008 (after 5 weeks of blood and mucous) and still flaring
Canasa 1000 mg suppositories and 2 tsp smooth texture Metamucil nightly
25 mg hydrocortisone suppositories and 1 Garden of Life Primal Defense Ultra in a.m.
Effexor 37.5, Remeron 30 mg, Clonazepam .5 mg (or more) and Trazodone 75 mg for sleep/anxiety
2.5 mg methimazole for thyroid
Trying acupuncture
Osteopenia and other assorted ailments


Scarlet504
Regular Member


Date Joined Oct 2008
Total Posts : 192
   Posted 10/30/2008 10:49 PM (GMT -6)   

I have taken Celexa last year after I quit smoking, because the smoking cessation gave me depression and anxiety. I started Celexa while I was flaring, but the flare wasn't too bad and it disappeared shortly while being on Celexa. I was on it around 6 months and then tapered off.

I wanted to start Celexa around 4 weeks ago and I have the worst flare of my life so far right now. Within two days on Celexa (50 mg), my flare got even worse, especially the bleedings. So I only took half a pill for the next two days and I got a little better. When I went taking 50 mg again, the bleeding got so much worse again (I went from around 12 bloody BMs to 30+). I stopped taking Celexa, only took it a week total and I am scared of going back again. I don't even want to consider another antidepressant right now.

I am not sure if the increased bleeding was caused from Celexa or if it was coincidence, but when I lowered the dose, the bleedings got a little better. It is hard to tell when you are in a full blown flare up. Anyway, just be careful and if you notice any worsening in your flare, you better talk to your doctor if the Celexa could be the culprit. Especially look out for tarry and black stools - I had them, too. Maybe you can consider taking something like Xanax for the anxiety? I take it occasionally when the anxiety gets overhand and I personally prefer taking something on a "as needed" basis for anxiety when I have a choice in that matter. If you suffer from depressions, too or GAD (generalized anxiety disorder), you are probably better off with long-term treatment as in antipressants.

Hope you feel better soon!


Pancolitis since 3/1997
Worst flare of my life since 8/2008, finally showing improvement!!
 
Meds (as in 10/2008)
12 x Asacol a day
40 30 25 mg Prednisone
Align (just started)
Flintstones Complete Vitamins (just started - tummy doesn't like the "adult" vitamins)
Cortenema


quincy
Elite Member


Date Joined May 2003
Total Posts : 25775
   Posted 10/31/2008 2:10 AM (GMT -6)   
Hi..I wouldn't worry about it since most of the meds we're on can cause gastro bleeding for some of us.

Try the Celexa and see if it helps. If it does, that's awesome!!

You might consider to take it in the evening wih a full meal rather than the morning...but I'm basing that on the fact that when I was on it for only a week...I couldn't function at all because I was so lethargic. i was on the lowest dosage. Anxiety wasn't the problem as much as the depression...once I was on the Effexor, I felt better. No problems with that as of yet either.

quincy
*Heather* Status..Asacol 6 (3 twice daily); enemas every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 4(Natural Factors Protec) bedtime + Primadophilus Reuteri Pearls occasionally
~multi-digestive enzymes as needed
~Ranitidine,Pariet (reflux);  Effexor XR 75mg(depression);  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!
 


suebear
Forum Moderator


Date Joined Feb 2006
Total Posts : 5419
   Posted 10/31/2008 8:04 AM (GMT -6)   
I took Celexa for 4 years after I had jpouch surgery. I did not suffer any side effects and found it to be a miracle drug for my depression. As with any SSRI it might take some trial and error to find the one that works best for you with the least amount of side effects. Everyone responds to them differently.

Sue
dx proctitis in 1987
dx UC in 1991, was stable until 1998

1998 started prednisone, asacol, pentasa, nortriptylene, ativan, 6MP, rowasa enemas and suppositories, hydrocortisone enemas, tried the SCD diet, being a vegetarian, omega 3s, flax, pranic healing, yoga, acupuncture, probiotics

2000 lost all my B-12 stores and became anemic

2001 opted for j-pouch surgery- now living life med-free


quincy
Elite Member


Date Joined May 2003
Total Posts : 25775
   Posted 10/31/2008 10:18 AM (GMT -6)   
absolutely Sue.....I only tried 3 (Effexor XR, Paxil...felt horrific on it, and Celexa...sleepy all the time). Effexor XR is amazing for me.

q
*Heather* Status..Asacol 6 (3 twice daily); enemas every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotic 4(Natural Factors Protec) bedtime + Primadophilus Reuteri Pearls occasionally
~multi-digestive enzymes as needed
~Ranitidine,Pariet (reflux);  Effexor XR 75mg(depression);  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!
 


bokscarracer
Regular Member


Date Joined Sep 2008
Total Posts : 149
   Posted 10/31/2008 2:44 PM (GMT -6)   
wow thanks so much for the responses everyone! i might have to think about asking to try the effexor. i've been pretty lethargic myself lately since i started the 20mg celexa last friday. i'm still only popping one every other day. i've also had some icky mud butt with a yellow liquid. don't know if my gallbladder is leaking or what. anyways, i feel so blessed to have come across this site. it really helps having that connection with other uc'ers. i always tell myself i'd rather have this disease now than to have been five years-old with leukemia or something! i guess i'm trying to think positively?

julee70
Regular Member


Date Joined Oct 2007
Total Posts : 475
   Posted 11/2/2008 3:56 PM (GMT -6)   
I would read a lot about Effexor and ask a lot of questions before trying it. Some people have a lot of trouble getting off it. (Google Effexor and "brain zaps" and you'll find some interesting side effects reported from people trying to get off it.)

I took Celexa (generic) for years and it did not seem to have an adverse impact on my UC. If anything, it made it better since I was happier and more relaxed. I took a very low dose -- maybe 5 mg a day -- and it made big difference.
-------
UC for the last ten years
Current Meds: 6MP since 2006, Cortifoam
Past Meds: You name it; I've tried it. (Asacol, Colazol, Pentasa, DiPentum, Rowasa, Canasa, Cortenema, sulfasalazine)
5ASA drugs don't work for me. Canasa seems to make me worse.
Alternative treatments I have had success with: Acupuncture, Hypnotherapy


Terps19
Veteran Member


Date Joined Jul 2005
Total Posts : 1425
   Posted 11/12/2008 11:08 AM (GMT -6)   

UC, Crohns, Microscopic colits and most other inflammatory diseases are intensified and sometimes seem worse when you are depressed and have anxiety all the time. 

Usually I find that I flare when I am stressed or drepressed, maybe this starts the hightened inflammatory response and leads to a flare but I am not sure.  I do know that I always feel better when I do not have anxiety and my depression is controlled.

I was DX'd with UC about 3-4 years ago and that really scared the crap out of me.  Depression and anxiety went thru the roof and I flared even bigger and harder.  My PCP put me on Wellbutrin and Ativan (wellbutrin has a lower chance of D being a side effect) and ativan to calm my nerves.  Since I have moved and have a new pcp that is telling me that combo is a bad one.  So we tried a few SSRIs (paxil and zoloft) and those only made my D worsen which in turn increases anxiety and drepression.   The next one to try is Celexa but I think I might just skip to Effexor (less chance of D) and not try the Celexa.

SSRIs can cause D, especially Paxil, and in some studies it even shows that it causes undetermined colitis in up to 40% of patients.  When I found this out Paxil was gone.  My mom suffered from a ton of D when she was on Paxil.

All that being said, I will keep trying to find that magic bullet for me that will keep me happy without the added D.  My symptoms are almost nonexistant when my mood is good.  When my mood is bad then I start to feel physically ill.

Good luck! 


March 2005 Dx'd with Ulcerative colitis
Took: asacol, colazal, rowasa, entocort, VSL probiotic
2.14.06 Test results positive for gluten and dairy sensativity! (enterolab)
July 2006 normal c scope and biopsies
Taking: Wellbutrin 150 mg Ativan .5 mg as needed
Officially married!
Gluten Free Dairy free since May 20, 2006 and feeling great 

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