Where does the mucus come from?

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madabs
Regular Member


Date Joined May 2008
Total Posts : 384
   Posted 11/17/2008 9:14 AM (GMT -6)   
 
Ok, I can guess that it comes from the colon..........
 
But for those of us who pass a lot of it both with and without stool  - What is the most likely site of inflamation?  Can it be from anywhere in the colon or just in the lower portions of colon and/or rectum?
 
I'm tweaking my medications right now and knowing the answer may help me make  better choices. 
 
 
 
 
 
UC diagnosed 10/05, first symptoms 1983
asacol 12/daily and rowasa as needed 
Trying out Culturelle Probiotic
past rx: colozal, lialda, canasa
i can't complain, but sometimes i still do.  lifes been good to me so far.  -joe walsh


Christine1946
Veteran Member


Date Joined Aug 2008
Total Posts : 5915
   Posted 11/17/2008 9:22 AM (GMT -6)   
     When starting a flare, mucus is the first thing I notice.  I have ulcerative proctitis, so I would guess it comes from the lower portion of the colon.
62 yr old granny. South Jersey
Diagnosed with ulcerative proctitis in 1998 in hospital
Hospitalized (2nd time) in May 2008
Update 11/03/08...finally in remission!!  Hope I don't jinx myself.  Off the prednisone since 11/01/08...now see if I can stay off for longer than two weeks.  Other meds: 6MP (75 mgm), colazal (6 per day), Benicar and Toprol (high blood pressure meds), Probiotic (2 per day), fish oil capsule and multi-vitamin and calcium with vitamin D.


Peety
Veteran Member


Date Joined Mar 2008
Total Posts : 2855
   Posted 11/17/2008 9:25 AM (GMT -6)   
it's been my understanding that if mucus is the first or only thing to come out it's the lower part of your colon that's inflamed and you need rectal meds.
49 year old female attorney, diagnosed UC/pancolitis 1985, no surgery but much suffering.
Asacol/5ASA 6x400 mg maintenance for 20+ years; use prednisone & Rowasa for flares. 
August 2008 sought care of naturopathic doctor. Food sensitivity test showed gluten, other intolerances; started diet without gluten, soy, dairy, tomato etc. Replete probiotic first, then Forte pills. 
Achieved remission for the first time in many, many years!? Seemed so, but colonoscopy Oct. 6 proved not so, heavy inflammation in ascending colon & will be using Rowasa again. But I AM better.
 
 


jujub
Forum Moderator


Date Joined Mar 2003
Total Posts : 10405
   Posted 11/17/2008 10:36 AM (GMT -6)   
The wall of the colon produces mucus throughout its length. The purpose is to lubricate the colon for easy passage of waste. People with healthy colons don't even notice the small amounts of mucus. When your colon is irritated, it produces more mucus to try to protect itself, and it becomes very visible.
Judy
 
Moderate to severe left-sided UC (21 cm) diagnosed 2001.
Avascular necrosis in both shoulders is my "forever" gift from Entocort.
Colazal,  Remicade, Nature's Way Primadophilus Reuteri. In remission since April, 2006.
"My life is an ongoing medical adventure"
 
Co-Moderator UC Forum
Please remember to consult your health care provider when making health-related decisions.


31fan
Regular Member


Date Joined Feb 2007
Total Posts : 34
   Posted 11/17/2008 11:52 AM (GMT -6)   
When I first flared, all I had coming out was mucus, and the c-scope showed pancolitis. So it doesn't necessarily mean the inflammation is localized.
Diagnosed with UC in transverse and descending colon in Feb. 2007
Doing well so far on Asacol 800 mg. 2x a day
Also take 25 mg. Paxil, 100 mg. Wellbutrin, 1 probiotic pearl per day
Back on 12.5 mg. Paxil to prevent post-partum depression.
Pregnant, to be induced July 1, 2008.
 


pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20577
   Posted 11/17/2008 2:12 PM (GMT -6)   
People with IBS can get mucus too and there is no inflammation with IBS...
 
However, the large bowel mucus layer effectively prevents contact between the highly concentrated luminal bacteria and the epithelial cells in all parts of the normal colon. Colonic inflammation is always accompanied by breaks in the mucus barrier. Although the inflammatory response gradually reduces the number of bacteria in mucus and faeces, the inflammation itself is not capable of preventing bacterial migration, adherence to and invasion of the mucosa.

 

In UC, the mucus membrane of the intestine becomes inflamed and develops ulcers. These ulcers bleed and produce pus and mucus, which may be visible as they are passed in the stool. In IBS, there may be increased mucus production by the lining of the intestine, which is then passed. Mucus is more often associated with diarrhea-predominant IBS. Mucus is less frequent with CD, but may be associated with the development of an anal fissure.



:)


My bum is broken....there's a big crack down the middle of it! LOL :)

Post Edited (pb4) : 11/17/2008 1:22:43 PM (GMT-7)


landcruiser
Regular Member


Date Joined Jun 2008
Total Posts : 80
   Posted 11/17/2008 2:42 PM (GMT -6)   
If you just have watery cloudy(mucus) exulsions with no stool and no blood, does that mean UC or IBS. Right now that is the biggest complaint.....several nighttime mucus movements...no stool and once or twice during the day...how do you stop that if it is IBS? on Remi and no steroids.....GI says my colon is not relasing enough water..Is that from damage? Any tips on how to stop the mucus production would be great appreciated....formed stool most days...very little blood, and what is there he says is from Hemmies....any help to stop the watery cloudy discharge...on garden of life pro biotics too and a fiber supplement.....Maddening to have this going on at night....

quincy
Elite Member


Date Joined May 2003
Total Posts : 29650
   Posted 11/17/2008 4:02 PM (GMT -6)   
basically....it's increased activity in the colon that creates the excess mucus. It could be a mechanical defect in how the colon acts/reacts as in IBS. . It could be from inflammation as in infection or UC or CD, MC...etc or it could be from IBS. Both can cause spasming in the colon..and the apasming can cause the increased activity which causes more mucus. Some will get more mucus without increased expulsion, some would get increased expulsion and mucus...could be only mechanical, could be disease, could be both....

clear as mud.

I think for either, an antispasmodic and fibre supplement and probiotic can help.

quincy
*Heather* Status..Asacol 6 (3 twice daily); enemas every 4th night
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals/supplements 
~Probiotics....(Natural Factors Protec 2 or 3  +   1 or 2 Primadophilus Reuteri Pearls @ bedtime
~multi-digestive enzymes as needed
~Ranitidine,Pariet (reflux);  Effexor XR 75mg(depression);  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!
 


pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20577
   Posted 11/17/2008 4:21 PM (GMT -6)   
Definitely fibre supplements, probiotics and bee propolis has aided my mucus issues, execessive mucus is no longer an issue for me.

:)
My bum is broken....there's a big crack down the middle of it! LOL :)


madabs
Regular Member


Date Joined May 2008
Total Posts : 384
   Posted 11/18/2008 7:44 AM (GMT -6)   

Thanks everyone for your input.

I guess mucus is a symptom of many things and too hard to pin down exactly.  To be expected of slime I suppose.

I do take fiber and a probiotic.  This sudden reappearance of "mucus bombs" yeah as someone in this forum so eloquently put it, is colitis related because I definitely feel something brewing in my guts and I keep seeing blood more and more as well.  Rowasa to the rescue I hope!

Take care!
UC diagnosed 10/05, first symptoms 1983
asacol 12/daily and rowasa as needed 
Trying out Culturelle Probiotic
past rx: colozal, lialda, canasa
i can't complain, but sometimes i still do.  lifes been good to me so far.  -joe walsh

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