I had a slip disc had to take Advil, can I take my mesalamine Apriso?Quincy Question for you

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therearemiracles
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Date Joined Dec 2006
Total Posts : 2930
   Posted 4/5/2010 10:40 AM (GMT -7)   
Has anyone started taking Apriso? i had to take an anti flammatory for my slipped disc, can I go ahead and take my medication as well?
 
Quincy, do you know if the medication start to work, can your body produce more mucus in repairing itself? When I started taking this med, I would have a lot of mucus (pinkish in color coming out but no stool, just liquid mucus)
 
Thanks,
 
Linda
Very mild left sided (could have fooled me with the "mild")  UC.Just found out 4 years into it I might have Lyme's Disease, going to a LLMD in December. Confirmed Lymes on 12/8/09 before my new antibiotic protocal from my LLMD, I  Started and stopped LDN ON 1/25/09 to mid May no improvements. Tried Asacol, Pentesa, Colozol, Sulfasulsadine and Lialda, they made me worse. A range of antibiotics (for 10 days here and there), not much better. Supplements: No UC meds at this time. Started Doxy and Cedfinir too rough on stomach, stopped those.Started Bicillin injection 1/12/10, once a week of injections.On Zithromax and Flagyl as well, about 2 year protocol to rid myself of bacteria Babesia, Chylmadia Phenomia and Borresliosis. Taking Oxy Aloe Flush and liquid vitamins, curcumin and CO Q10


fruitgirl
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Date Joined Feb 2009
Total Posts : 6980
   Posted 4/5/2010 10:47 AM (GMT -7)   
Apriso (or other mesalamines) don't interact negatively with NSAID's...the reason UCers are advised not to take them is because of increased risk of bleeding. At least that's my understanding. If you're feeling nervous about it, contact your GI or pharmacist. You also might want to speak with a doctor about a non NSAID pain managment alternative.

I'm on Apriso, and am doing very well on it.
Co-Moderator, UC Forum
Status: Remission since May 2009!
Symptoms began in November 2008, ~4 weeks after giving birth to my son
Diagnosed with pancolitis on 1/30/09
Meds: Apriso (4 0.375g pills ONCE!! daily), mesalamine enema twice weekly, Natural Factors Ultimate probiotic 12/12 Formula, multivitamin.  Used prednisone (starting dose 40 mg) to get into remission.
 
 


therearemiracles
Veteran Member


Date Joined Dec 2006
Total Posts : 2930
   Posted 4/5/2010 10:55 AM (GMT -7)   
Hi FG
 
Do you take your meds at night or in the morning?
 
Thanks,
 
Linda
Very mild left sided (could have fooled me with the "mild")  UC.Just found out 4 years into it I might have Lyme's Disease, going to a LLMD in December. Confirmed Lymes on 12/8/09 before my new antibiotic protocal from my LLMD, I  Started and stopped LDN ON 1/25/09 to mid May no improvements. Tried Asacol, Pentesa, Colozol, Sulfasulsadine and Lialda, they made me worse. A range of antibiotics (for 10 days here and there), not much better. Supplements: No UC meds at this time. Started Doxy and Cedfinir too rough on stomach, stopped those.Started Bicillin injection 1/12/10, once a week of injections.On Zithromax and Flagyl as well, about 2 year protocol to rid myself of bacteria Babesia, Chylmadia Phenomia and Borresliosis. Taking Oxy Aloe Flush and liquid vitamins, curcumin and CO Q10


fruitgirl
Veteran Member


Date Joined Feb 2009
Total Posts : 6980
   Posted 4/5/2010 11:21 AM (GMT -7)   
In the morning, with breakfast, mostly because it's easier to remember then. I basically always eat breakfast at home, but sometimes eat out for supper.
Co-Moderator, UC Forum
Status: Remission since May 2009!
Symptoms began in November 2008, ~4 weeks after giving birth to my son
Diagnosed with pancolitis on 1/30/09
Meds: Apriso (4 0.375g pills ONCE!! daily), mesalamine enema twice weekly, Natural Factors Ultimate probiotic 12/12 Formula, multivitamin.  Used prednisone (starting dose 40 mg) to get into remission.
 
 


therearemiracles
Veteran Member


Date Joined Dec 2006
Total Posts : 2930
   Posted 4/5/2010 12:58 PM (GMT -7)   
Thanks I noticed when taking two, I'm working my way up to 4 as prescribed, I have indigestion problem, and bad gas. Did you ever get this and did it go away? Thank you
Very mild left sided (could have fooled me with the "mild")  UC.Just found out 4 years into it I might have Lyme's Disease, going to a LLMD in December. Confirmed Lymes on 12/8/09 before my new antibiotic protocal from my LLMD, I  Started and stopped LDN ON 1/25/09 to mid May no improvements. Tried Asacol, Pentesa, Colozol, Sulfasulsadine and Lialda, they made me worse. A range of antibiotics (for 10 days here and there), not much better. Supplements: No UC meds at this time. Started Doxy and Cedfinir too rough on stomach, stopped those.Started Bicillin injection 1/12/10, once a week of injections.On Zithromax and Flagyl as well, about 2 year protocol to rid myself of bacteria Babesia, Chylmadia Phenomia and Borresliosis. Taking Oxy Aloe Flush and liquid vitamins, curcumin and CO Q10


fruitgirl
Veteran Member


Date Joined Feb 2009
Total Posts : 6980
   Posted 4/5/2010 1:00 PM (GMT -7)   
Nope. I went from Asacol 12 pills/day straight to Apriso 4 pills/day. Sorry I can't help more on that!
Co-Moderator, UC Forum
Status: Remission since May 2009!
Symptoms began in November 2008, ~4 weeks after giving birth to my son
Diagnosed with pancolitis on 1/30/09
Meds: Apriso (4 0.375g pills ONCE!! daily), mesalamine enema twice weekly, Natural Factors Ultimate probiotic 12/12 Formula, multivitamin.  Used prednisone (starting dose 40 mg) to get into remission.
 
 


thatfield
Veteran Member


Date Joined Jul 2008
Total Posts : 822
   Posted 4/5/2010 1:40 PM (GMT -7)   
I was told not to take NSAID's with Lialda b/c not only are they bad for UC but Lialda can have a side-effect of causing bleeding as can NSAID's.  Lialda is not asprin based but apparently has some similar chemical make-up to asprin.  I do not know about Apriso though - I would call your doctor and ask.

Dx 2006 right after the birth of my daughter, currently pregnant with #2!
Lialda 3 pills a day
Rowasa Nightly
Prenatal Vitamins
 


quincy
Elite Member


Date Joined May 2003
Total Posts : 25891
   Posted 4/5/2010 1:58 PM (GMT -7)   
Hi Linda...what NSAID are you taking for your slipped disc?

I've not been on Apriso, but it is in the 5ASA med category which hasn't agreed with you in the past.

Your stomachache could be from flaring in general or from the NSAID.

I'd say the increased pinkish mucus is from flaring...and yes, it would produce more in the "effort" to protect itself. It is a sign that it's hurting, however.

Are fibre supplements and probiotics something you can use as well?

How about rectal meds? What options do you have there?

quincy

therearemiracles
Veteran Member


Date Joined Dec 2006
Total Posts : 2930
   Posted 4/5/2010 2:03 PM (GMT -7)   
Hi Heather,
 
I use probiotics, and Advil is what I used today for my inflammation of my slipped disc in my back.
 
I'm taking antibiotics much better, compared to before, so I thought I would try again. What UC oral drug is not a 5ASA please?
 
Thanks,
 
Linda
 
Very mild left sided (could have fooled me with the "mild")  UC.Just found out 4 years into it I might have Lyme's Disease, going to a LLMD in December. Confirmed Lymes on 12/8/09 before my new antibiotic protocal from my LLMD, I  Started and stopped LDN ON 1/25/09 to mid May no improvements. Tried Asacol, Pentesa, Colozol, Sulfasulsadine and Lialda, they made me worse. A range of antibiotics (for 10 days here and there), not much better. Supplements: No UC meds at this time. Started Doxy and Cedfinir too rough on stomach, stopped those.Started Bicillin injection 1/12/10, once a week of injections.On Zithromax and Flagyl as well, about 2 year protocol to rid myself of bacteria Babesia, Chylmadia Phenomia and Borresliosis. Taking Oxy Aloe Flush and liquid vitamins, curcumin and CO Q10


AZYooper
Veteran Member


Date Joined Mar 2010
Total Posts : 1180
   Posted 4/5/2010 2:05 PM (GMT -7)   
I would not take any NSAID especially Advil or aleve especially if in a flare. I have disc problems and took Aleve for a number of years. It definitely aggravated my UC. I know literally dozens of people that have had GI bleeding problems using Nsaids especially advil and aleve. When I stopped using it I realized it was doing really nothing to improve my condition. Ice and hot pad + back exercises with a strong pain reliever like vicodin or percocet when needed is far better. CCFA warns against nsaid use and so do some doctors if you have colitis. I don't even take aspirin anymore. I do miss that for headaches. NSAIDs have been implicated recently in causing cardiac inflammation.
Diagnosed with proctosigmoiditis as my 50th birthday present Dec 2009
4.8 grams Asacol HD plus 1000mg canasa daily for 8 weeks
Now on 1.6 gr Asacol HD daily


quincy
Elite Member


Date Joined May 2003
Total Posts : 25891
   Posted 4/5/2010 2:16 PM (GMT -7)   
Sheesh, I should read the titles much better, d'oh....sorry Linda!

Yeah, advil or Aleve...not good. I have permission from my doc to take aspirin...but promised to never ever again take advil. I took it for periods, once a month, but after my hysterectomy...didn't need it, thankfully!

Maybe for your slipped disc you could take Robaxacet? It has a muscle relaxant in it....plus wear a support around your torso.

The only oral non-5ASA meds is Entocort which is a steroid. As well, there are rectal steroids.

But, the other option could be sulfasalazine? it does have a 5ASA, but maybe the sulfa in it would be of assistance for your joint pain and back since it seems to have antiinflammatory properties.

quincy

fruitgirl
Veteran Member


Date Joined Feb 2009
Total Posts : 6980
   Posted 4/5/2010 2:20 PM (GMT -7)   
Azathioprine and 6MP aren't 5-ASA's.....right?
Co-Moderator, UC Forum
Status: Remission since May 2009!
Symptoms began in November 2008, ~4 weeks after giving birth to my son
Diagnosed with pancolitis on 1/30/09
Meds: Apriso (4 0.375g pills ONCE!! daily), mesalamine enema twice weekly, Natural Factors Ultimate probiotic 12/12 Formula, multivitamin.  Used prednisone (starting dose 40 mg) to get into remission.
 
 


AZYooper
Veteran Member


Date Joined Mar 2010
Total Posts : 1180
   Posted 4/5/2010 2:20 PM (GMT -7)   
This should scare you. Warning for Motrin(Ibuprofin the same as advil):

Gastrointestinal Effects - Risk of Ulceration, Bleeding, and Perforation

NSAIDs, including MOTRIN tablets, can cause serious gastrointestinal (GI) adverse events including inflammation, bleeding, ulceration, and perforation of the stomach, small intestine, or large intestine, which can be fatal. These serious adverse events can occur at any time, with or without warning symptoms, in patients treated with NSAIDs. Only one in five patients, who develop a serious upper GI adverse event on NSAID therapy, is symptomatic. Upper GI ulcers, gross bleeding, or perforation caused by NSAIDs occur in approximately 1% of patients treated for 3-6 months, and in about 2-4% of patients treated for one year. These trends continue with longer duration of use, increasing the likelihood of developing a serious GI event at some time during the course of therapy. However, even short-term therapy is not without risk. NSAIDs should be prescribed with extreme caution in those with a prior history of ulcer disease or gastrointestinal bleeding. Patients with a prior history of peptic ulcer disease and/or gastrointestinal bleeding who use NSAIDs have a greater than 10-fold increased risk for developing a GI bleed compared to patients treated with neither of these risk factors. Other factors that increase the risk of GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. Most spontaneous reports of fatal GI events are in elderly or debilitated patients and therefore, special care should be taken in treating this population.
Diagnosed with proctosigmoiditis as my 50th birthday present Dec 2009
4.8 grams Asacol HD plus 1000mg canasa daily for 8 weeks
Now on 1.6 gr Asacol HD daily


therearemiracles
Veteran Member


Date Joined Dec 2006
Total Posts : 2930
   Posted 4/5/2010 2:21 PM (GMT -7)   
Thanks so much, I will try to stick with the Apriso and see how I do. My inflammation is less when I'm on it however, I get trapped gas and indigestionand I will get burst of diarreah and it will hit me and I have to go right then or else a accident happens.
 
I'll keep you posted.
 
Thanks again,
 
Linda
Very mild left sided (could have fooled me with the "mild")  UC.Just found out 4 years into it I might have Lyme's Disease, going to a LLMD in December. Confirmed Lymes on 12/8/09 before my new antibiotic protocal from my LLMD, I  Started and stopped LDN ON 1/25/09 to mid May no improvements. Tried Asacol, Pentesa, Colozol, Sulfasulsadine and Lialda, they made me worse. A range of antibiotics (for 10 days here and there), not much better. Supplements: No UC meds at this time. Started Doxy and Cedfinir too rough on stomach, stopped those.Started Bicillin injection 1/12/10, once a week of injections.On Zithromax and Flagyl as well, about 2 year protocol to rid myself of bacteria Babesia, Chylmadia Phenomia and Borresliosis. Taking Oxy Aloe Flush and liquid vitamins, curcumin and CO Q10


quincy
Elite Member


Date Joined May 2003
Total Posts : 25891
   Posted 4/5/2010 2:22 PM (GMT -7)   
Right fruitgirl....they're systemic oral meds, immunosuppressants. Different category, still UC meds.
As usual, I'm thinking topical.

q

wodin
Regular Member


Date Joined Jul 2009
Total Posts : 498
   Posted 4/5/2010 3:20 PM (GMT -7)   
Advil is a brand of ibuprofen like Tylenol, and is generally well tolerated by Ucers. Ibuprofen is also usually an ingredient in more heavy duty pain relievers like Percocet and Vicodin.

Aleve is Naproxen sodium, and for me is a no-no. It's a shame too, as Naproxen was my favorite analgesic. It lasts for 12 hours! Taking Naproxen sodium for me is a sure fire path to a flare.

quincy
Elite Member


Date Joined May 2003
Total Posts : 25891
   Posted 4/5/2010 3:26 PM (GMT -7)   
Ibupropfen is NOT recommended for UCers...most doctors poo-poo it...seriously.

Nothing is really good for most who have AI disease....most of us have pain. Tylenol, not good for the liver, Ibuprophen not good for the kidneys. Balancing act, although I would say once in a while would be OK.

Aspirin...well, a miracle med and a menace....I seem to tolerate it very well, at least I have options.

q

AZYooper
Veteran Member


Date Joined Mar 2010
Total Posts : 1180
   Posted 4/5/2010 3:29 PM (GMT -7)   
Tylenol is acetaminophen. Advil is ibuprofen which is a NSAID like aleve.
Diagnosed with proctosigmoiditis as my 50th birthday present Dec 2009
4.8 grams Asacol HD plus 1000mg canasa daily for 8 weeks
Now on 1.6 gr Asacol HD daily


Red_34
Forum Moderator


Date Joined Apr 2004
Total Posts : 22185
   Posted 4/5/2010 7:27 PM (GMT -7)   
Have you ever slipped a disc before? What are your symptoms? I have two bulging discs in my neck and I get cortisone injections to help alleviate the pain and swelling. But once in a while, even while on injections, my neck hurts a bit so I use ice to help reduce swelling. I have also been given the ok by my GI to take Celebrex for my arthritis which helps my neck as well as the rest of my body. Of course Celebrex is not usually recommended for Uc'ers either but I don't seem to have a problem with it but then again, I am in remission. Another thing that might help is Salonpas. These are otc pain killing adhesive pads. They work pretty well on pain as long as you don't have any neuropathies.
 @--->--SHERRY--<---@
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(6 daily),6mp(50-100mgs),Bentyl, Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate ALL mesalamines**~Allergies-Singulair, Zyrtec~Secondary Reynauds Syndrome~Sacroiliitis~bulging and herniated discs C5/C6 & C6/C7~Epidural injections (2 series of 3), OA (hands and spine)-Tylonel Arthritis, Celebrex, Fibromyalgia (diagnosis pending)
To help Healingwell - click here: DONATE
 
 
 
 
 

 
 


fruitgirl
Veteran Member


Date Joined Feb 2009
Total Posts : 6980
   Posted 4/5/2010 10:46 PM (GMT -7)   
Ooooh yeah to Salonpas. They help tremendously with all sorts of aches!
Co-Moderator, UC Forum
Status: Remission since May 2009!
Symptoms began in November 2008, ~4 weeks after giving birth to my son
Diagnosed with pancolitis on 1/30/09
Meds: Apriso (4 0.375g pills ONCE!! daily), mesalamine enema twice weekly, Natural Factors Ultimate probiotic 12/12 Formula, multivitamin.  Used prednisone (starting dose 40 mg) to get into remission.
 
 


quincy
Elite Member


Date Joined May 2003
Total Posts : 25891
   Posted 4/6/2010 2:03 AM (GMT -7)   
Never heard of Salonpas....but, the main ingredient is methylsalicylate...which is wintergreen. A cousin to aspirin..both being salicylates.

Again, if one is sensitive to salicylates, dont use them.

Wonder if they're in Canada? Thanks fruitgirl! seems they could be a good option rather than taking oral.

q

fruitgirl
Veteran Member


Date Joined Feb 2009
Total Posts : 6980
   Posted 4/6/2010 9:19 AM (GMT -7)   
I can't take aspirin (rips my gut to shreds, and always has) but Salonpas don't bother me at all.
Co-Moderator, UC Forum
Status: Remission since May 2009!
Symptoms began in November 2008, ~4 weeks after giving birth to my son
Diagnosed with pancolitis on 1/30/09
Meds: Apriso (4 0.375g pills ONCE!! daily), mesalamine enema twice weekly, Natural Factors Ultimate probiotic 12/12 Formula, multivitamin.  Used prednisone (starting dose 40 mg) to get into remission.
 
 


quincy
Elite Member


Date Joined May 2003
Total Posts : 25891
   Posted 4/6/2010 2:06 PM (GMT -7)   
will put that on my list to investigate.....doesn't give your skin any grief?

q

Red_34
Forum Moderator


Date Joined Apr 2004
Total Posts : 22185
   Posted 4/6/2010 2:24 PM (GMT -7)   
The Salonpas doesn't cause my skin to burn like other adhesives. I can't use bandaids because they burn my skin. The only thing, like I mentioned, is if one has neuropathies, it can aggravate it. Yes, learned that the hard way! lol I can't take aspirin but Salonpas doesn't bother me either.
 @--->--SHERRY--<---@
Moderator for Allergies/Asthma and Co-moderator for UC
~Left sided Uc-'92-Colazal(6 daily),6mp(50-100mgs),Bentyl, Prilosec,Biotin,Forvia,Pro-Bio**Unable to tolerate ALL mesalamines**~Allergies-Singulair, Zyrtec~Secondary Reynauds Syndrome~Sacroiliitis~bulging and herniated discs C5/C6 & C6/C7~Epidural injections (2 series of 3), OA (hands and spine)-Tylonel Arthritis, Celebrex, Fibromyalgia (diagnosis pending)
To help Healingwell - click here: DONATE
 
 
 
 
 

 
 


fruitgirl
Veteran Member


Date Joined Feb 2009
Total Posts : 6980
   Posted 4/6/2010 3:51 PM (GMT -7)   
Nope, they don't bother my skin, either. And I'm the type that if I have to wear a bandaid for more than a couple of days, my skin gets icky, I guess because of the adhesive.
Co-Moderator, UC Forum
Status: Remission since May 2009!
Symptoms began in November 2008, ~4 weeks after giving birth to my son
Diagnosed with pancolitis on 1/30/09
Meds: Apriso (4 0.375g pills ONCE!! daily), mesalamine enema twice weekly, Natural Factors Ultimate probiotic 12/12 Formula, multivitamin.  Used prednisone (starting dose 40 mg) to get into remission.
 
 

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