I just want to clarify my position a little clearer. I am a big fan of the rectal meds, wheter it's enemas or suppositories depending on high or low the inflammation is. I too had pancolitis and the ASA meds weren't doing anything for me. The imuran healed my colon well and I am trying to wean myself off the Imuran and get on rectal meds only. It's very important what is being said. The rectum is where uc starts and where it ends. The thinking is that if one can control this area then one can keep a good grip on their colitis. I initially started on 200 mg of Imuran and then lowered it to 150 mg with no noticeable effects. I have since added Canasa since there is only a small patch of inflammation in my rectum. My GI doc and I made a deal. I will stay on the Canasa for the next six months and do a flex scope in late spring. If that area has healed then I am to lower my Imuran dosage to 100 mg.
The point I am trying to make is that I don't like being on Imuran. But I don't like having UC either. If I have to live with this uc thing then I will Imuran as necessary but ideally I would like to be just on rectal meds. Imuran as a drug has worked very well for me thus far and it has it's place but rectal meds are good too.