Generic Mesalamine vs Lialda

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hateuc
Veteran Member


Date Joined Jun 2010
Total Posts : 2269
   Posted 9/13/2017 12:09 PM (GMT -6)   
Interesting thread. They tried to pass off generic on me too but fortunately I opened the bag there...noticed it and told them no thanks. I have the savings card so as long as that works, I will stick with what I am doing. Please do keep us all posted if anyone tries the generic.
B

MarjieKay
Veteran Member


Date Joined Jun 2017
Total Posts : 609
   Posted 9/13/2017 12:14 PM (GMT -6)   
The enemas I use are generic and seem to have been fine for me.
F, 51
2008 colitis, 2016 chronic UC, 2017 quiescent UC
Current pharms: Pentasa 3g day, mesalamine enema (1 x per wk)
Anti-inflammatory diet :IBD-AID from U of Mass

Extras:
Advanced gut health probiotics, Primadophilis Reuteri, water & milk kefir
Digestive enzymes (big protein meals only now), Psyllium seed powder, Ginger Tea
Vitamins D, C & K, fish oil, cal/mag

hateuc
Veteran Member


Date Joined Jun 2010
Total Posts : 2269
   Posted 9/13/2017 6:04 PM (GMT -6)   
I agree, the generic enemas work for me!!
B
UC diagnosed in 2010 but had prob. in 2009
2 Lialda/day Rowasa nightly, periodic anucort supp, Cortifoam as needed(needed more than I would like)
VSL#3, slippery elm
Metamucil capsules
Trying Gluten free (why not!)

Lgreco
New Member


Date Joined Sep 2017
Total Posts : 5
   Posted 9/18/2017 8:51 PM (GMT -6)   
How is everyone doing on generic?

iPoop
Forum Moderator


Date Joined Aug 2012
Total Posts : 10557
   Posted 9/19/2017 6:20 AM (GMT -6)   
Good, no issues.
Moderator Ulcerative Colitis
John
, 39, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; daily 75mgs 6MP, 4.8g generic-Lialda, and rowasa

Must've been a barking-spider!

UCdee
New Member


Date Joined Jul 2016
Total Posts : 9
   Posted 9/21/2017 6:35 AM (GMT -6)   
Having bad reaction to generic- just taking it for 3 days. I'm calling doc today and going back to Lialda. Glad to see this post, I really didn't know what happened! Back to urgent watery b/ms last two days.

JewelsOK
Regular Member


Date Joined Jun 2007
Total Posts : 364
   Posted 9/24/2017 6:11 PM (GMT -6)   
Anymore updates? My son just started it this past week, but is slowly switching over by taking 3 Lialda & 1 generic for a week, then going to do 2 & 2 for a while, then 1 Lialda and 3 generic, etc. until his supply of name brand runs out.

So far so good, but it's early!
Julie

Mom of Son 26 UC dx at age 10, Lialda x3, Azathioprine 175 mg, Iron, Protein Supplements.

Daughter 18 UC dx at age 8, Colazal x6, 6MP 25/37.5 mg, Prozac, Florastor, Culturelle, Iron, Vit/Min.

turtlepower
Regular Member


Date Joined Oct 2011
Total Posts : 232
   Posted 9/25/2017 7:41 AM (GMT -6)   
I was fighting a mini flare on Saturday, but I do not attribute it to the generic. It was a super hot day (Which always has the potential to give me problems) and made the mistake of having grapefruit juice. D'oh!

Other than that, no real problems. *Knocking on the biggest piece of lumber I can find*

Bigwill63
New Member


Date Joined Oct 2017
Total Posts : 1
   Posted 10/2/2017 9:12 AM (GMT -6)   
The generic lialda seems to be hurting my remission as well. Starting to get more urgency and inflammation going on. I was down to 2 a day for the last year along with biweekly enemas and all was good. Switched about 4 weeks ago. Upping my dosage and hopefully will help. I called the pharmacy to get brand name and it looks like the perscription savings card is ending October 15th. Bummer

iPoop
Forum Moderator


Date Joined Aug 2012
Total Posts : 10557
   Posted 10/2/2017 9:19 AM (GMT -6)   
The prescription savings card for lialda is good for one year at a time, call them (or request another online) to get another card for another year. There's no limits on how many years you can have a card! Some of us have had cards for many years!
Moderator Ulcerative Colitis
John
, 39, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; daily 75mgs 6MP, 4.8g generic-Lialda, and rowasa

That walk we do, due to post-public-restroom-embarassment, from our awful poop-spolsion in the bowl that flushing alone won't fully hide. Quiet, sly, and as near of a direct-path to the exit as possible...

beanie15
Regular Member


Date Joined Apr 2012
Total Posts : 42
   Posted 10/8/2017 7:14 AM (GMT -6)   
I have also been switched to the generic and before starting, I wanted to see how everyone else was doing. I still have a couple of weeks worth of Lialda. Been on it without issue since 2009.
My 90 day supply was only $30 co-pay and when I picked up my script from CVS it was only $15. I didn't realize I was switched until I got home, thought my doc only renewed for 45 days as I'm due to see her soon.

Just started a mild flare. Fun how this disease just keeps us guessing!

I will post with results if I have any problems with the generic.

Lgreco
New Member


Date Joined Sep 2017
Total Posts : 5
   Posted 10/16/2017 11:19 AM (GMT -6)   
Now that the Lialda savings card is over, I'm afraid generic may be my only option moving forward. For the past week, I've been taking half generic, half Lialda to test it out. No noticeable difference besides more frequent BM, but I've also upped fiber in my diet.

UCinGV
Regular Member


Date Joined Mar 2007
Total Posts : 385
   Posted 10/16/2017 1:30 PM (GMT -6)   
My employer is trying to push everyone into HSA/HDHP plans and phasing out their PPO starting at the end of 2019. The big problem with this for me, of course, is buying Lialda out of pocket. Currently my PPO is charging me $40 and paying $1124. (I also found out I was switched to the generic without me noticing. Before three months ago I was paying $250 and insurance paid $1296.)

So, in anticipation of being pushed into an HSA plan, I started looking at these prices. Someone showed me this app called "GoodRX" where you can find the place with the cheapest prices. This app says that 180 pills of generic Lialda "Mesalamine DR" is $1100 at Costco (close to what I'm paying with my insurance company's mail order) and $463 at Walmart.

Can that be right? Is there that big of a difference in prices or is the drug at Walmart different?

Before I go down there and buy some, how can I be sure that any "generic Lialda" I am buying has the same delivery mechanism as brand name Lialda?

Is "Mesalamine DR" the official generic name for Lialda with the delivery mechanism of Lialda?

iPoop
Forum Moderator


Date Joined Aug 2012
Total Posts : 10557
   Posted 10/16/2017 2:27 PM (GMT -6)   
Zydus Pharmaceuticals produces both generic-lialda and generic-asacohd.

www.zydususa.com/product-details/?id=307

www.zydususa.com/product-details/?id=216
Moderator Ulcerative Colitis
John
, 39, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; daily 75mgs 6MP, 4.8g generic-Lialda, and rowasa

Told my dentist I'd rather see him than my gasteroenteroligist. He said he'd take that as a compliment smile

JohnnyUC
New Member


Date Joined Nov 2016
Total Posts : 4
   Posted 10/17/2017 8:46 AM (GMT -6)   
I Switched to the generic 2 months ago. Blood and mucus came back. My GI asked if anything had changed and i told him i was taking the generic lialda. He said to switch back. have gone back to name brand and symptoms disappeared. there is supposed to be an allowable 1% difference in formula. so i am willing to pay the extra $20 for the name brand.

Glasw55
New Member


Date Joined Apr 2012
Total Posts : 6
   Posted 10/17/2017 8:53 PM (GMT -6)   
Has anyone that has been on Lialda and in remission had success taking the generic brand? I can't afford to have a flare, last flare was horrific and caused me permanent damage to my spine due to side effects of Prednisone, and I don't want to go on Humira or any other serious drug.

Don't think that taking these drugs are without risk. I've been on Lialda for 4+ years and it has been keeping me stable, took Asacol before that and flared every year. The release system of Lialda differentiates how it works compared with Asacol. They are both Mesalamine but work completely different in how the medicastioj is released into your system.

Anyway, I'm very wary in having to go the generic route but if I stay on Lialda, it will cause me to eventually go broke. My insurance won't cover much of the cost now and Lialda stopped their co-pay program. This is really disheartening to say the least.

iPoop
Forum Moderator


Date Joined Aug 2012
Total Posts : 10557
   Posted 10/18/2017 6:32 AM (GMT -6)   
I've been fine on Generic Lialda. Often switching between mesalamines is uneventful (and most pharmacists and doctors will say there's minimal difference), but some can have issues with it. There are no guarantees in life, you can certainly try it and switch back to the brandname if it becomes a necessity.

I think having an affordable medication is key as you're most likely to take it as recommended (and not take less of the brandnamed med and have adverse reactions as a consequence, say 3 pills a day instead of 4 or whatever).

There's several generics available that are mesalamine with delayed-release coatings. There's Mesalamine DR 800MG (generic Asacol HD) and Mesalamine DR 1200MG (generic Lialda).

Other generics that are a more complex molecule that is broken down to mesalamine and a byproduct by your gut bacteria. They're older medications but a lot more affordable than the above mentioned meds. The end result is the same, it's just not a MMX polymer that delivers the medication to the target location, rather gut bacteria cleave apart complex molecules to deliver mesalamine.
1.) Balsalazide disodium (generic of ColazalĀ®)
2.) Olsalazine (generic of DipentumĀ®)
3.) Sulfasalazine

One way or another, there is an affordable means to take a UC medication that will help you maintain your remission. Talk with your doctor about what is affordable and I am sure he/she can prescribe something that is cost effective. For example, Sulfasalazine is less than $100 a month without any insurance.

Cheers!
Moderator Ulcerative Colitis
John
, 39, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; daily 75mgs 6MP, 4.8g generic-Lialda, and rowasa

Told my dentist I'd rather see him than my gasteroenteroligist. He said he'd take that as a compliment smile

Post Edited (iPoop) : 10/18/2017 6:37:58 AM (GMT-6)

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