should i take probiotics while taking antibiotics?

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bananagirl
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Date Joined May 2011
Total Posts : 4320
   Posted 3/24/2012 6:11 AM (GMT -6)   
i just started a course of flagyl, 4 tablets of 500 mg a day. should i be taking a probiotic along with this? i have read conflicting info on this. some say that the flagyl will kill off the good and bad bacteria so i good to keep replenishing the healthy bacteria so the bad bacteria doesn't take over again when you're done the antibiotics. others say that the good bacteria in the probiotics will get killed while you are taking the antibiotics so it's a waste of money and to just take them when you are done your course. what are your thoughts on this? i'm really open to all answers as i have no idea. are there studies showing that a certain method is best?
Joanna, 22
current meds: remicade every 8 weeks- not working at all.
other epic fails- canasa supps, prednisone, 6mp, rowasa, lialda, cortico enemas, l-glutamine.
having lots of diarrhea and urgency ever since i took a 2 week break from my probiotics and got a concussion. dumbest decision ever.

deltaforce
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Date Joined Jun 2010
Total Posts : 1841
   Posted 3/24/2012 6:21 AM (GMT -6)   
My understanding is, probiotics (bacteria) are not antibiotics resistant so they WILL get killed when you are on antibiotics. So personally, I do not take probiotics when I am on antibiotics and start them 4 days after the antibiotics course completion.
Diagnosed March 2007 with left sided UC at the age of 30.
Currently on,
Colazal 9 daily, Imuran, 200mg daily, Vit. B12, 1mg, Multivitamin, 1 tablet daily, Fish oil 2400mg daily, Vit D 2000 IU daily.

Verapamil 240mg for migraine, Migraine episode now at least twice a month,
Ibuprofen 400mg is the only solution (but leads to bleeding). Looking for alternatives.

Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2732
   Posted 3/24/2012 6:29 AM (GMT -6)   
Antibiotics generally put me into flares, beginning with giving me D and cramps at best if I am lucky- however, if I take heavy doses of probiotics at opposite times of the day (or, at least 2 hours apart from the times when I take antibiotics in any case) from my probiotics, I find the bad, undesired side effects of the antibiotics are lessened and the chances of going into a full fledged flare are less- so I always take them with gusto when on antibiotics. I recall reading once that sacharomyces boulardi is one of the tougher probiotics in terms of not being killed off by anti-, so it would be a good one to add on those occasions- IMO. Of course, in all cases I would definitely keep up the heavy probiotics for some period after you finish the antibiotics, to replenish.

bananagirl
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Date Joined May 2011
Total Posts : 4320
   Posted 3/24/2012 6:47 AM (GMT -6)   
deltaforce, that's what i usually do- wait til im off antibiotics- but i've been reading a lot of info saying to take with them. it's so confusing! haha

probiotic, i do have some sacro b in my fridge. i have been taking probiotics every day but stopped yesterday when i started my antibiotics. im just in a terrible flare and my reason for asking for antibiotics is that maybe they will kill of all the bacteria and i can just start over again with a ton of good probiotics. do you know anything about prebiotics? i plan on ordering them because i most likely need them.
Joanna, 22
current meds: remicade every 8 weeks- not working at all. flagyl for 10 days
other epic fails- canasa supps, prednisone, 6mp, rowasa, lialda, cortico enemas, l-glutamine.
having lots of diarrhea and urgency ever since i took a 2 week break from my probiotics and got a concussion. dumbest decision ever.

sherbear46
Forum Moderator


Date Joined Jun 2011
Total Posts : 2642
   Posted 3/24/2012 9:28 AM (GMT -6)   
I still took my probiotic while I was on my zpac but I had known I was going to go on it so I took extra a week prior. I also took the antibiotic in the afternoon and the probiotic before bed. I did not flare or have any symptoms at all. :)
Co-Moderator UC

Sheri-39 years old

Diagnosed April 2009-suffered over a year prior to diagnosis

Currently taking Lialda 2 tabs in am, Protonix 40mg every day, Allegra, Zyrtec, Probiotics, Vitamin D3, Melatonin and Rowasa enema once a week.

Currently in Remission since June 2011. I seem to flare yearly Dec/Jan time frame. Hoping this winter to be different since I'm not working.

i_love_coffee
Veteran Member


Date Joined May 2010
Total Posts : 635
   Posted 3/24/2012 11:14 AM (GMT -6)   
bannanagirl: some probiotics have prebiotics in them.  benebiotics and jarrows sacch boulardi both have pre biotics in them.
UC dx 1991, have had it throughout colon in patches CURRENT:4inch isolated patch of inflamation in recto-sigmoid
Meds: Lialda , Entocort, Hydrocort/rowasa, omeprazole. weaning off oral entocort
fiber supp ,calcium, fish oil,multivit
jarrows sach. boul. probiotic,benebiotics, slippery elm
Diet: lactose intolerant Limit: sugar/alcohol/high acid foods/gluten. gluten free 2/24

killcolitis
Veteran Member


Date Joined Dec 2009
Total Posts : 2396
   Posted 3/24/2012 11:31 AM (GMT -6)   
I would take florastor definitely. It's an antibiotic resistant yeast and is recommended when taking something like flagyl. If you're going to take any other probiotics, take them at least 2 hours away from your abx.

InSoFla
Veteran Member


Date Joined Jan 2011
Total Posts : 4679
   Posted 3/24/2012 12:15 PM (GMT -6)   
Joanna,

Definitely take probiotics, and also s. boulaardi as well. But take them at least 4-5 hour away from the time you take your probiotics.

IMO, if you wait until you finish your antibiotics, then your gut will be in very bad shape since the antibiotics kill off all good gut flora.
Dx - UC 09/2010.Tried various Mesalamine enemas/suppos/pills with Prednisone for several rounds without any help.PaleoDiet of proteins,veggies,salads, fruits, & protein shakes w/almond milk, Liquid Minerals& Vitamins,Maca powder,L-Glutamine 15g, D-Ribose 5g,L-ArgEthylEster,chia seeds,VSL#3,K2,VIt. D3 100,000 IU every 10 days.Transdermal LDN put me remission!

ItsAlwaysSomething
Veteran Member


Date Joined Oct 2011
Total Posts : 1407
   Posted 3/24/2012 12:26 PM (GMT -6)   
There is a lot of info regarding the use of both anti and probiotics (at the same time) on the website
www.livestrong.com
Female, Retired
Diagnosed pancolitis 12/2003, Colazal generic (balsalazide), mesalamine (Rowasa generic) enemas as needed.
Benebiotic and Jarrow S Boulardii probiotics, vitamins, slippery elm bark, chia seeds, L-Glutamine and LDN.
Working toward a more organic, gluten-free, lactose-free diet.
Goals: (1) REDUCE INFLAMMATION (2) KEEP A SENSE OF HUMOR

deltaforce
Veteran Member


Date Joined Jun 2010
Total Posts : 1841
   Posted 3/24/2012 12:39 PM (GMT -6)   
@ InSoFla,

Usually antibiotics are dosed in such a way that the high serum level of antibiotics is maintained almost throughout the day. So taking antibiotics will probably survive yeast but certainly not bacteria. Actually, that is just waste of money. It takes about 3/4 days for the system to clear off all antibiotics (of course depends on the one and formulation). Hence I wait for 4 days. If she is going to take probiotics 4-5 hours away from antibiotics course, most likely it will be time for next dose of antibiotics (which will act faster than probiotic). Its the serum level of antibiotics that kills bad (and good) bacteria so no matter when you take them, as long as your serum level is high enough to kill bad bacteria, good ones are going to the coffin as well.

If the gut is going to be in bad shape at the end of antibiotics course, it WILL, no matter you take them or not (unless yeast is the one that is helping you a lot).
Please correct me if I am wrong in my understanding.

InSoFla
Veteran Member


Date Joined Jan 2011
Total Posts : 4679
   Posted 3/24/2012 12:54 PM (GMT -6)   
Delta,

In my experience, and when I checked with my doctor, she confirmed about the importance of taking the probiotics along with antibiotics, BUT at least 4-5 hours apart (so she said).

Btw, did you see my response to you in the thread on lobster and glucosamine?
I am curious to hear your thoughts....
Dx - UC 09/2010.Tried various Mesalamine enemas/suppos/pills with Prednisone for several rounds without any help.PaleoDiet of proteins,veggies,salads, fruits, & protein shakes w/almond milk, Liquid Minerals& Vitamins,Maca powder,L-Glutamine 15g, D-Ribose 5g,L-ArgEthylEster,chia seeds,VSL#3,K2,VIt. D3 100,000 IU every 10 days.Transdermal LDN put me remission!

pb4
Elite Member


Date Joined Feb 2004
Total Posts : 17835
   Posted 3/24/2012 1:33 PM (GMT -6)   
It's imparative that you take probiotics daily and indefinitely and especially since we are often perscribed antibiotics which completely clear the system of all bacteria (good and bad) making it that much more vulnerable for bad bacteria to move in and wreak havoc.

They key is to take your probiotics at least 2 hours after your done taking your antibiotics for the day so that the antis don't kill off the probiotics...it's basically a must.
bee propolis caps 500mg one cap twice/day
omegas 369 caps one cap twice/day
probiotics 10 billion cfu once/day
vitamins C-calcium ascorbate (easy on the gut) and vitamin A each once/day
Prodiem fibre supplement one cap before bed
I've also altered my diet (no junky stuff at all, processed, fast-foods, refined sugars, ect) and exercise regularly.
I went from 30+ bloody BM's/day with lots of lower back pain to an average of 5/day no bleeding no back pain and completely formed stools, still have severe urgency issues.
~~~~~~~~My bum is broken....there's a big crack down the middle of it! LOL :)~~~~~~~~

tstoll
New Member


Date Joined Sep 2012
Total Posts : 1
   Posted 9/11/2012 7:25 AM (GMT -6)   
I am on Flagyl and Bactrim. Flagyl three times a day and Bactrim twice a day. I usually take the two at 7 am, the Flagyl again at 1 pm., and the two again at 6 pm. When should I take my probiotic?

InSoFla
Veteran Member


Date Joined Jan 2011
Total Posts : 4679
   Posted 9/11/2012 10:20 AM (GMT -6)   
Welcome to the forum.
 
The general rule is 4 hours APART from when antibiotics are taken.
 
Let me know how else we can help you.
Rx meds didn't help me. But 4.5 mg LDN +Paleo diet +supplements=REMISSION.Protein shakes w/almond milk,Maca powder,L-Glutamine,D-Ribose,chia seeds.VSL#3,K2,VIt. D3,slippery elm bark powder.For more info,my protocol is the 11th post at this link: http://www.healingwell.com/community/default.aspx?f=38&m=1666318
If you have any questions, you can find my email address at my profile.

quincy
Elite Member


Date Joined May 2003
Total Posts : 25572
   Posted 9/11/2012 12:48 PM (GMT -6)   
Take the probiotics at bedtime.

q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

Denvermom
New Member


Date Joined Sep 2012
Total Posts : 1
   Posted 9/11/2012 1:39 PM (GMT -6)   
I am having my third flare, and this time I am ahead of the curve. I started taking a Probiotic immediately, and my flare seems to be staying mild. I am taking Mesalamine suppositories, no coffee, wine, gluten. Seems to be stalled, and the probiotics are keeping me pretty mobile without worry of the bathroom triangulation. The probiotic is called Bio-V, made by a local woman from around here in Denver. I has a special coating to make it through your digestive system and release in in your large instestine....pretty cool.

pb4
Elite Member


Date Joined Feb 2004
Total Posts : 17835
   Posted 9/11/2012 2:11 PM (GMT -6)   
Yeah, it's a good idea to take a good probiotic daily and indefinitely...flaring or not, since we IBDers are prone to bacterial overgrowth.
bee propolis caps 500mg one cap twice/day
omegas 369 caps one cap twice/day
probiotics 10 billion cfu once/day
vitamins C-calcium ascorbate (easy on the gut) and vitamin A each once/day
Prodiem fibre supplement one cap before bed
I've also altered my diet (no junky stuff at all, processed, fast-foods, refined sugars, ect) and exercise regularly.
I went from 30+ bloody BM's/day with lots of lower back pain to an average of 5/day no bleeding no back pain and completely formed stools, still have severe urgency issues.
~~~~~~~~My bum is broken....there's a big crack down the middle of it! LOL :)~~~~~~~~

soystud
Veteran Member


Date Joined Jan 2004
Total Posts : 4663
   Posted 9/11/2012 2:44 PM (GMT -6)   
short answer = yes
diagnosed with pancolitis december 21, 2003
currently taking: -- Astaxanthin, Ultimate Flora Critical Care, Natures Way Reuteri, Wild Harvest Inflamma Shield, Multi Vit. -
No Gluten, Limited Rice, Corn, Dairy & Sugar - -
1 x 800mg asacpl/day
Lots of H2O, exercise as much as possible & enjoy this great life that God has blessed me with -
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