Shingles, Azathioprine, and Ulcerative Colitis

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UCinGV
Regular Member


Date Joined Mar 2007
Total Posts : 363
   Posted 3/30/2012 8:07 AM (GMT -6)   
I'm 29 and taking 100mg of Azathioprine daily for my UC. I broke out with a nasty rash on Sunday which turned out to be shingles!!! Ughh. I'm now taking the antiviral Valacyclovir pills and I'm just wondering, could this have been caused by my taking the azathioprine? What is the likelihood of it coming back? And are there any interactions with ulcerative colitis?

Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2732
   Posted 3/30/2012 10:03 AM (GMT -6)   
My wife (who does not have UC) got hit by shingles for the first and only time in her life a couple years back... It was vicious and painful but it did subside week by week (she was put on the same drug) and was basically all gone after a month. We researched at the time and although there are some rare instances of recurring shingles, most episodes seem to be a one time thing. Hang in there- it will pass and it sounds like you are doing the right things.

UCinGV
Regular Member


Date Joined Mar 2007
Total Posts : 363
   Posted 3/30/2012 10:47 AM (GMT -6)   
Probiotic said...
My wife (who does not have UC) got hit by shingles for the first and only time in her life a couple years back... It was vicious and painful but it did subside week by week (she was put on the same drug) and was basically all gone after a month. We researched at the time and although there are some rare instances of recurring shingles, most episodes seem to be a one time thing. Hang in there- it will pass and it sounds like you are doing the right things.


Thanks for your reply. I'm glad to hear from other people going through this, and to hear that that recurrences are rare. I really just want to complain! I'm so pissed. RRRRRHHHGGGHHH!

quincy
Elite Member


Date Joined May 2003
Total Posts : 25596
   Posted 3/30/2012 11:19 AM (GMT -6)   
I do hope this is a one-off...but it would also depend on what other exposures you might have to bring it out.

Have you recently had x-rays or been sick with a flu, or have had extreme distress/stress, or took a holiday and travelled? etc...

I've read that L. lysine is also a good thing to take for any herpes viruses...
How long are you to be on the antiviral? 

q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

UCinGV
Regular Member


Date Joined Mar 2007
Total Posts : 363
   Posted 3/30/2012 12:04 PM (GMT -6)   
quincy said...
I do hope this is a one-off...but it would also depend on what other exposures you might have to bring it out.

Have you recently had x-rays or been sick with a flu, or have had extreme distress/stress, or took a holiday and travelled? etc...

I've read that L. lysine is also a good thing to take for any herpes viruses...
How long are you to be on the antiviral?

q

The doctor said I would be on for ten days but gave me a refill in the unlikely event I still needed more.

No flu. But I was tearing out my old kitchen floor the day before the pain really started hitting me, which was probably the stress trigger. Until visiting the doctor I thought I had inhaled some weird mold under the old vinyl floor which caused me to get the rash.

X-rays --- now that you mention it, I did just have some dental X-rays taken last week.

nightside of eden
Veteran Member


Date Joined Sep 2009
Total Posts : 518
   Posted 3/30/2012 6:30 PM (GMT -6)   
i had the shingles last month, and was on pred, and lialda at the time took the antiviral drug and clear up in two weeks.... it just popped up, and hurt like hell

ByeByeUC
Veteran Member


Date Joined Feb 2011
Total Posts : 3066
   Posted 3/30/2012 6:36 PM (GMT -6)   
I broke out with a case of shingles when I was on Remicade so that was definitely because my immune system was suppressed. Shingles is nasty...hope yours clears up soon!
Marianne

DX UC - in 2005 when I was 37
Tried every drug-even Remicade-Tried diets-nothing worked-wanted my life back!
Step 1: J-pouch surgery (Laparoscopic restorative proctocolectomy w/ temporary diverting loop ileostomy) 6-25-10
Step 2: Take down surgery (Ileostomy reversal) 10/8/10
No more UC!!! Very happy with my results of this surgery-got my life back! :)

Anthonyv
Regular Member


Date Joined Jul 2011
Total Posts : 153
   Posted 3/31/2012 12:53 AM (GMT -6)   
i got shingles a couple of years ago whilst taking azathioprine, not fun at all
Adelaide, Australia

19 year old male

Osteoporosis diagnosed june 2011 thanks to extensive prednisolone use

crohns colitis disease diagnosed 2000

moderate - severe left sided colitis - 2011

current status : flaring, been better, been worse!

current meds - Colazide 3 x 3 daily, azathioprine 175mg, nexium 20mg, prednisolone 25mg

Old Hat
Veteran Member


Date Joined Feb 2007
Total Posts : 4512
   Posted 3/31/2012 2:15 AM (GMT -6)   
Anyone who had chicken pox can later develop shingles-- because it's caused by reactivation of the dormant herpes virus that remains in one's body after the pox heals. Doctors think that stress plus weakening of one's immune system can lead to shingles; in fact, an anti-shingles vaccine is now recommended for seniors in the U.S. since many cases of the disorder have been hitting elderly people here in recent decades. Seniors apparently are more likely to develop complications from shingles, such as recurrent pain along nerve paths where the rash developed. Taking the anti-viral med should help you to avoid complications. Best wishes for a speedy recovery! / Old Hat (31 yrs with left-sided UC; presently in remission taking brandname Colazal)
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