Sunlight Endorphins, perhaps it is not the Vitamin D

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Old Mike
Veteran Member


Date Joined Jan 2007
Total Posts : 2471
   Posted 4/12/2012 2:49 PM (GMT -6)   
While looking into how LDN works, I was interested in what other ways that you can raise endorphin levels.
 
It turns out one of them is sunlight.
 
Then I start to wonder since LDN works well on IBD and other autoimmune diseases, and there is a
North/South gradient for UC which would appear to be exposure to the sun,what might really be going on.
Perhaps it is not just vitamin d from the sun but increased endorphin levels that produce a lessening of symtpoms in the summer for some people.
Ways to increase endorphins are,eating fat,chocolate,laughter,excercise,sun,LDN,hot peppers on the tongue.
Trying to figure out how increased endorphins work on the immune system is another story.
Also trying to figure out how to up regulate endorphins besides LDN,or decrease what destroys them.
Perhaps something to think about.
Here is an interesting blog about coffee and opioid receptors,seems interesting,I drink 1 cup a day.
Old Mike
 
 
 
 
 
 

Post Edited (Old Mike) : 4/12/2012 3:19:47 PM (GMT-6)


ItsAlwaysSomething
Veteran Member


Date Joined Oct 2011
Total Posts : 1407
   Posted 4/12/2012 7:00 PM (GMT -6)   
When I was younger, I would do several tanning sessions before going on vacation to Mexico.
I felt that "endorphin high" after 30 minutes in the tanning bed...:-)
Female, Retired
Diagnosed pancolitis 12/2003, Colazal generic (balsalazide), mesalamine (Rowasa generic) enemas as needed.
Benebiotic and Jarrow S Boulardii probiotics, vitamins, slippery elm bark, chia seeds, L-Glutamine and LDN.
Working toward a more organic, gluten-free, lactose-free diet.
Goals: (1) REDUCE INFLAMMATION (2) KEEP A SENSE OF HUMOR

aguywithuc
Veteran Member


Date Joined Jun 2010
Total Posts : 2459
   Posted 4/13/2012 1:00 AM (GMT -6)   
Thanks for posting this. I have always liked the beach, prefer to ski these colorado mountains when its a sunny day and always like to go outside when its sunny. I should have used more sun block. This could explain why I like it so much and do not care for grey overcast days.

InSoFla
Veteran Member


Date Joined Jan 2011
Total Posts : 4679
   Posted 4/13/2012 7:24 AM (GMT -6)   
OldMike,
 
Thanks for posting this.
Very interesting.
 
Of course, LDN does not need vit. d3 to work efficiently (at least not that the researchers have discovered yet).
Dx - UC 09/2010.Tried various Mesalamine enemas/suppos/pills with Prednisone for several rounds without any help.PaleoDiet of proteins,veggies,salads, fruits, & protein shakes w/almond milk, Liquid Minerals& Vitamins,Maca powder,L-Glutamine 15g, D-Ribose 5g,L-ArgEthylEster,chia seeds,VSL#3,K2,VIt. D3 100,000 IU every 10 days.Transdermal LDN put me remission!

InSoFla
Veteran Member


Date Joined Jan 2011
Total Posts : 4679
   Posted 4/13/2012 7:46 AM (GMT -6)   
OldMike,
 
I thought you might find this interesting:
 
 
there's a video that explains how LDN works.
 
What do you think?
Dx - UC 09/2010.Tried various Mesalamine enemas/suppos/pills with Prednisone for several rounds without any help.PaleoDiet of proteins,veggies,salads, fruits, & protein shakes w/almond milk, Liquid Minerals& Vitamins,Maca powder,L-Glutamine 15g, D-Ribose 5g,L-ArgEthylEster,chia seeds,VSL#3,K2,VIt. D3 100,000 IU every 10 days.Transdermal LDN put me remission!

beatUC
Veteran Member


Date Joined Mar 2010
Total Posts : 1125
   Posted 4/13/2012 7:50 AM (GMT -6)   
interesting. since i've had UC I crave the sun, even on hot days.
Imuran
Asacol
prednisone as needed

Old Mike
Veteran Member


Date Joined Jan 2007
Total Posts : 2471
   Posted 4/13/2012 9:20 AM (GMT -6)   
Thanks InSoFla: I understand the rebound effect.What I am trying to do is make the connection between LDN/endorphins,the Sun/endorphins,endorphins in general and UC. Since LDN works, without extra vitamin d, and it is believed that there is a North South gradient, and possibly a seasonal difference in UC symptoms, I am starting to wonder that the doc's are wrong and it is not the vitamic D from the sun but endorphins.
The other question of course is what are the endorphins doing with the immune sys, the biochemical pathways are many and perhaps not well understood,and difficult to sort out.
Old Mike

Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2741
   Posted 4/13/2012 11:49 AM (GMT -6)   
Mike- as always, thanks for pursuing all these lines of inquiry- ya just never know. I coukdnt find much re. Seasonal variation- indeed this study suggests none- mahbe a slight increase in flares in the spring, which one could guess might be delayed onset of sunlight deficiency, but that correlation was very weak.

http://www.ncbi.nlm.nih.gov/pubmed/14988820
"In order to save the village organ, we had to destroy remove it" -- Doctor's Prescriber's proverb. 
 

therearemiracles
Veteran Member


Date Joined Dec 2006
Total Posts : 2929
   Posted 4/13/2012 3:23 PM (GMT -6)   
oldmike did you try the combo antibiotic therapy? I can't remember. I don't see anything in your signature line. I'm on LDN too right now, cream. Are you capsules or cream?
UC since '05, asacol,LDN, L-glutamin, flora balance, florastor, super bio curcumin,DHEA, 5-lox inhibitor (boswellia), astaxathin, Vit d3 (spray)

Old Mike
Veteran Member


Date Joined Jan 2007
Total Posts : 2471
   Posted 4/13/2012 4:03 PM (GMT -6)   
Therearemiracles: I don go to GI doc's so hard to get LDN,that is one reason I am trying to figure out what is going on with LDN, and if there is any other way to upregulate endorphins besides LDN.
I was on 37 days of cipro last year, did nothing, have been on flagyl and amox at the same time, no change in UC. Although bactrim DS seems to do something,but effect does not last. I will give a update in a week or so if I continue to improve on fish/fish oil,no veggie oils,kerry butter,grass fed milk.
Old Mike

Post Edited (Old Mike) : 4/13/2012 3:31:15 PM (GMT-6)


SS0000
Veteran Member


Date Joined Feb 2012
Total Posts : 670
   Posted 4/13/2012 4:21 PM (GMT -6)   
WITH UC I CRAVE SUN TOO

Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2741
   Posted 4/13/2012 9:53 PM (GMT -6)   
Mike- rest assured, no GI is going to rx, and few will approve of, LDN- one needs to see a so-called alternative med doc to get an LDN rx- however, there are links on LDn sites on how to order regular naltrexon from a Mexican pharmacy and then dilute it down into LDN at home.
"In order to save the village organ, we had to destroy remove it" -- Doctor's Prescriber's proverb. 
 

DanthaMan
Regular Member


Date Joined May 2005
Total Posts : 467
   Posted 10/7/2012 7:23 AM (GMT -6)   
I would like to comment about this thread. I have gone on a cruise the past three years in May, June, and Sept down to the Caribbean. The past two years when I went I was in bad shape before I left. I am thinking that its probably due to the stress of worrying about having problems which in itself is counterproductive! Last year I was drinking a lot of mint mojitos and noticed that my tummy actually did really well while I was on the trip. I thought hey looks like mint helps let me get a peppermint supplement to see if that works. Didnt replicate the success. This year I was having a lot of D before we left it came out of nowhere so I remembered that I had a D supplement that I havent really used before called Diarreha Relief or something like that it has Clay, Charcoal, and Apple Pectin as the only ingredients. I started that on saturday and the cruise was the next day. It seemed to help calm things down but on Monday besides the normal active morning I went 8 hours without even thinking about the bathroom. That day we spent all day in the sun, I did put on suncreen but only once and it was SPF 15. All week during the cruise I enjoyed lots of alcohol, sun and no tummy issues. Fast forward to reality and back home things are going back to the way they were before the trip. I am doing the exact same protocol, I even ate gluten and diary on the trip everday. I am pretty confident that Old Mike is correct in his assumption about sunlight and endorphins based on my experience two years now. I do notice that it seems the lower the SPF the better I feel which makes sense.

Old Mike
Veteran Member


Date Joined Jan 2007
Total Posts : 2471
   Posted 10/7/2012 7:57 AM (GMT -6)   

Seems to be a day for digging up old info.

Glad you found this thread usefull.
Kind of difficult to separate the effects of vitamin D and endorphins from sunlight,which one is it or both, that helps.
Have taken large doses of vitamin D for extended time,does not seem to help.
Old Mike


stereofidelic89
Veteran Member


Date Joined Sep 2011
Total Posts : 1923
   Posted 10/7/2012 9:43 AM (GMT -6)   
InSoFla, can I ask how often you administer LDN? In the video it says the positive rebound effects will continue to last for 18 hours.
Diagnosed Crohns-Colitis Sept 2011
Gluten Free, VSL#3, InflaGuard, Zyflamend, Asacol
Metametrix Labs stool testing reveal yeast overgrowth/parasite
Two Month Protocol: Candida Control Diet, Phytostan, ParaGuard, ADP
Results: Stools are firm, no aches, normal bowel habits and less cravings

freddyj
Veteran Member


Date Joined Aug 2011
Total Posts : 1168
   Posted 10/7/2012 10:56 AM (GMT -6)   
Old Mike said...
Therearemiracles: I don go to GI doc's so hard to get LDN,that is one reason I am trying to figure out what is going on with LDN, and if there is any other way to upregulate endorphins besides LDN.
I was on 37 days of cipro last year, did nothing, have been on flagyl and amox at the same time, no change in UC. Although bactrim DS seems to do something,but effect does not last. I will give a update in a week or so if I continue to improve on fish/fish oil,no veggie oils,kerry butter,grass fed milk.Old Mike



So Does this mean you are not worried about milk fats? And that sounds good, like you are improving? Not to change the subject, but I think I have improved on turmeric the past few days.

Old Mike
Veteran Member


Date Joined Jan 2007
Total Posts : 2471
   Posted 10/7/2012 11:49 AM (GMT -6)   
The processed milk fat could be a problem, not sure.
Best for me is a reduction in veggie oils and the use of fish oil.
I still need to get Meriva which is curcumin mixed with PC for better absorbtion.
Old Mike

InSoFla
Veteran Member


Date Joined Jan 2011
Total Posts : 4679
   Posted 10/7/2012 12:34 PM (GMT -6)   
Stereo,

You take LDN every night, whether orally or via transdermal application.
Rx meds didn't help me. But 4.5 mg LDN +Paleo diet +supplements=REMISSION.Protein shakes w/almond milk,Maca powder,L-Glutamine,D-Ribose,chia seeds.VSL#3,K2,VIt. D3,slippery elm bark powder.For more info,my protocol is the 11th post at this link: http://www.healingwell.com/community/default.aspx?f=38&m=1666318
If you have any questions, you can find my email address at my profile.

ColitisMastery
Regular Member


Date Joined Oct 2011
Total Posts : 188
   Posted 10/7/2012 7:58 PM (GMT -6)   
Old Mike,

Look into cis-urocanic acid, that has an immunomodulatory affect from UV exposure.

And I was wondering if you could write a quite note on what your diet and lifestyle modifactions are. You seem quite into the science of environmental effects on IBD and I'm curious to know what you do for your IBD.
Diagnosed at age 12 with ulcerative colitis in 2002. 21 years old with recent gallbladder surgery!.
Current daily meds
5-ASA
Vitamin D 6000 ui
Calcium 600 mg Magnesium 300 mg
1 packet of VSL #3
Vitamin B12 1000 mcg once a week
Raw kale/collard greens juice daily :D
Avoids: Eggs, gluten/wheat, aspartame, sucralose, food colouring and larges amounts of meats

Old Mike
Veteran Member


Date Joined Jan 2007
Total Posts : 2471
   Posted 10/8/2012 6:03 AM (GMT -6)   
Basically avoid veggie oils,take fish oil.
Just started B536 probiotic two weeks ago.
Will try mervia type curcumin as soon a I get some.
Still smoke on purpose.
Old Mike
New Topic Post Reply Printable Version
Forum Information
Currently it is Saturday, August 30, 2014 7:10 AM (GMT -6)
There are a total of 2,204,868 posts in 245,422 threads.
View Active Threads


Who's Online
This forum has 155293 registered members. Please welcome our newest member, yazka.
284 Guest(s), 8 Registered Member(s) are currently online.  Details
dfrty, PrayingForAMiracle, Judy2, SuperBlanks, FamilyGuy, Dr-A, soystud, bayou jackal


Follow HealingWell.com on Facebook  Follow HealingWell.com on Twitter  Follow HealingWell.com on Pinterest  Follow HealingWell.com on YouTube
Advertisement
Advertisement

©1996-2014 HealingWell.com LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer