What's the usual starting does of Imuran?

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Veteran Member

Date Joined Jun 2008
Total Posts : 867
   Posted 5/4/2012 9:54 PM (GMT -6)   
Reading some of the other threads here I've noticed alot of people saying they are upping their doses to 150mg.  I just noticed my doc prescribed a starting dose of 125mg, is this a normal starting dose?  What do most people start at and do you keep taking the same dose as long as its working for you or do you reduce it eventually?
Just curious as I see people saying they have nausea, and like others I HATE nausea! I'd rather throw up for an hour straight then have nausea for an entire day!
UC - diagnosed 1994, in remission for 10 years, currently getting over a flare
Meds: Colazal 3 pills/3x day, 1 mesalamine enema nightly, 2 probiotics/day, iron, calcium, folic acid

Veteran Member

Date Joined Aug 2004
Total Posts : 633
   Posted 5/4/2012 9:58 PM (GMT -6)   
Not sure on Imuran. 6mp starts at 50mg usually, but I know the dose for that is lower than with Imuran. Someone here will know....

I pray we don't get the nausea :)

Regular Member

Date Joined Mar 2003
Total Posts : 32
   Posted 5/4/2012 11:14 PM (GMT -6)   
There's some helpful info at this link:


Regular Member

Date Joined Jan 2012
Total Posts : 225
   Posted 5/5/2012 5:16 AM (GMT -6)   
I was started at 100 and then upped to 150.
Diagnosed with proctitis in 2010. Diagnosed with UC in sept. 2011.
Allergic to Asacol
finished prednisone (60mg) taper; all symptoms returned 1/2012; tried some alternative approaches
Began new round of prednisone (30mg) taper plus Imuran (150 mg).
Taking fish oil, glutamine, and VSL#3

Regular Member

Date Joined Jun 2010
Total Posts : 117
   Posted 5/5/2012 6:24 AM (GMT -6)   
most doctrors will proscribe imuran at a mini dose at first to see how you react to it as sometimes this drug has been known to cause serious complications like pancreatitis (not commonly tho). and if you have no serious side effects will up your dose. for most ppl this is around 150 mg per day but i believe they go by your body weight. at least thats what mine is. good luck!!!
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