Artificial sweeteners may cause Inflammatory Bowel Disease

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beatUC
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   Posted 5/18/2012 3:31 PM (GMT -6)   
"Inflammatory Bowel Disease (IBD), which includes Crohn’s Disease (CD) and Ulcerative Colitis (UC), may be initiated by saccharin and sucralose, found in Splenda. Splenda reduces good bacteria in the gut, and alters drug metabolism."

www.digitaljournal.com/article/325050

London_Gal
Regular Member


Date Joined May 2012
Total Posts : 46
   Posted 5/18/2012 3:38 PM (GMT -6)   
I think this is probably cr@p - these substances CAUSE bowel conditions? What about those people who have never ingested artificial sweeteners?And what about those who live on Diet Coke and still have no sign of IBD? However I would support the idea that artificial sweeteners - and indeed 'natural' sweeteners aka sugar, agave, honey et al - are no friend to the entire IBD spectrum.

lookforcure
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Date Joined Apr 2012
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   Posted 5/18/2012 4:06 PM (GMT -6)   
I have never used any artificial sweetners in my life, did not use much of any sugars but still got UC.
I still think that Splenda and other type of "fake" sweetners should be banned.

notsosicklygirl
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Date Joined Dec 2008
Total Posts : 10100
   Posted 5/18/2012 4:09 PM (GMT -6)   
I wouldnt be surprised if artifivial sweetners contributed to my development of uc but i dont think they alone caused it. I was probably genetically predisposed in the first place. Ive never done well after ingesting artificial sweetners. Now i cant eat them at all.

Also, i forgot to mention, uc was probably around before the invent of sweetners.

Sorry for the typos. I am on my phone.
Co-moderator: Ulcerative Colitis
Diagnosed with Pancolitis, Laryngopharyngeal Reflux & Migraines. Battling Extreme Exhaustion.
Currently: Asacol (2800mg) + 6mp (25mg) + Pristiq (50mg) + prilosec (40mg) +Canasa (1g PM) + cerazette

IamCurious
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Date Joined Jan 2010
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   Posted 5/18/2012 4:16 PM (GMT -6)   
Great article. Please remember that it is not saying that Splenda is THE ONE ABSOLUTE causative factor for IBD, but it makes an excellent case that it can be a contributing factor. Eating it doesn't help.
Male/60 DX ulcerative colitis Feb08, or maybe Crohn's colitis.
No Meds, allergic to Mesalamine. Remission since Mar10. Psyllium seed mixed with VSL3 is very helpful. Food journal instead of SCD.

Lots of fruit & vegetables (but no plums, kale, or carrots), no soda, no gluten, no HFCS, no xylitol or sorbitol, no trans fat, no shellfish, few processed foods, no carrageenan.
Probiotics, fish oil, multivitamin, extra D3, K2, high gamma E, phos choline, magnesium, boswellia, curcumin, glutamine.
Nature created all of the locks, therefore Nature has all of the keys

Sara14
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Date Joined Mar 2007
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   Posted 5/18/2012 4:46 PM (GMT -6)   
Wow, interesting. Thanks for posting!! I never ate much artificial sweetener but I did eat some in coffee and probably in processed foods where I didn't realize I was eating it. I can't wait to see more studies like this. I like to have something to blame. lol!

Post Edited (Sara14) : 5/18/2012 3:58:13 PM (GMT-6)


pb4
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   Posted 5/18/2012 5:06 PM (GMT -6)   
I'd say it could be a trigger for IBD, from what I've heard, people with IBS are suppose to avoid all sugar alcohols especially the ones ending in "tol" like sorbitol, xylitol, etc.

Trigger would be a better term to use, if one was predisoposed to getting an IBD, then artificial sweeteners could definitely be a trigger for some of them...according to researchers it's very likely that everyone's triggers for IBD will likely vary and possibly more than one environmental trigger would bring on the disease.
bee propolis caps 500mg one cap twice/day
omegas 369 caps one cap twice/day
probiotics 10 billion cfu once/day
vitamins C-calcium ascorbate (easy on the gut) and vitamin A each once/day
Prodiem fibre supplement one cap before bed
I've also altered my diet (no junky stuff at all, processed, fast-foods, refined sugars, ect) and exercise regularly.
I went from 30+ bloody BM's/day with lots of lower back pain to an average of 5/day no bleeding no back pain and completely formed stools, still have severe urgency issues.
~~~~~~~~My bum is broken....there's a big crack down the middle of it! LOL :)~~~~~~~~

London_Gal
Regular Member


Date Joined May 2012
Total Posts : 46
   Posted 5/18/2012 5:20 PM (GMT -6)   
pb4 said...
I'd say it could be a trigger for IBD, from what I've heard, people with IBS are suppose to avoid all sugar alcohols especially the ones ending in "tol" like sorbitol, xylitol, etc.


I would add to that substances ending in "ose" like fructose and glucose and sucrose and dextrose. Examine your packaging people! If it has an 'ose' on the end it's SUGAR!

bananagirl
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Date Joined May 2011
Total Posts : 4407
   Posted 5/18/2012 6:06 PM (GMT -6)   
in 8th grade and through high school, i was a Splenda addict. i probably ate 10 packets a day, usually in coffee and various other foods. my friend had told me how bad it was for you but i just didn't wanna believe him. he finally bought me a book called "Sweet Deception" by Dr. Mercola. i read it and immedicately stopped my Splenda usage. still, i was diagnosed with UC at 17 but don't contribute it to using sweeteners.
Joanna, 22
no meds. doing fecal transplant soon.
i'm taking- earth powder, probiotics, vit d, marshmallow root
tried- canasa, pred, 6mp, remicade, rowasa, lialda, cortico enemas, l-glutamine, vit e enema, VSL enema, aloe vera, NAG, prilosec, zofran, psyllium
diet- no meat, dairy, eggs, gluten. include-fresh juices, fruits, veggies, greens, grains, soy, beans, nuts/seeds

Christine1946
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Date Joined Aug 2008
Total Posts : 5465
   Posted 5/18/2012 6:15 PM (GMT -6)   
     I have used Sweet and Low for years and before that, saccharin.  I believe it is not good for you but don't think it contributed to my IBD.  My maternal grandmother was a diabetic and took saccharin in her coffee for years but never developed IBD.  I inherited those genes from my paternal side who never used a sugar substitute in their lives.

Old Mike
Veteran Member


Date Joined Jan 2007
Total Posts : 2451
   Posted 5/18/2012 6:49 PM (GMT -6)   
Posted the study a few weeks ago.
Anyhow I never ate any that I know about.
My wife drinks gallons of diet coke a week,no problem,her colon is pristine
via scope last year.
For some people perhaps it might be a problem,but believe it is something else.
Here is what I wrote in the other thread.
 
The basis of this theory is the reduction of gut bacateria activity due to saccharin, or other chemicals
that we ingest. Basically it is saying that there is not enough bacterial B-glucorunidase to
deconjugate bilirbuin,if the bilirbuin is not degonjuagated then the digestive proetases will not be deactived
Then the mucus barrier is destroyed,then the bacteria get to the mucosa, then the immune cascade
starts.
I am a big believer that we need a strong mucus barrier, and the loss is the real cause of UC.
There is some form of excess protease dissolving the mucus,whether from too many bacteria, that
exhibit protease, or not enough to deactivate digestive protease.
Will try and do more research on this,but might cut out milk.
Many have improved by cutting out dairy.
Old Mike
 

Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2738
   Posted 5/18/2012 8:12 PM (GMT -6)   
In addition to "-ose" substances, "-ols" such as mannitol can be bad news for IBDers.... i am shocked that flavored VSL3DS has mannitol, If I read someone's post correctly? Also, nanoparticles such as titanium dioxide can exacerbate UC according to at least one study- yet Mutaflor uses it in its enteric capsule- it amazes me that the designers of supplements for IBD can be that dumb, but they are.
"In order to save the village organ, we had to destroy remove it" -- Doctor's Prescriber's proverb. 
 

Lodi
Veteran Member


Date Joined May 2012
Total Posts : 680
   Posted 5/18/2012 10:11 PM (GMT -6)   
I agree, Probiotic, I was amazed at the ingredients list on Mutaflor! I'm still taking them though. I understood the chemical hard shell was necessary to make sure the probiotic got through to the bowel before it was digested.

Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2738
   Posted 5/19/2012 5:26 AM (GMT -6)   
Lodi- I understand, and if it helps you, definitely keep taking it. For some reason Mutaflor seemed to give me D and flare me up- I tried backing off and restarying but it happened again and again. i have a bunch of it in my fridge now that is a year and a half expired- tried some a couple weeks ago and it still had that effect, making me tnink it is still reasonably potent even though not expired. Toying with the idea of trying it in enemas instead of orally, instead of just throwing it all in the trash- as perhaps it is causing D via upsetting my small bowel and not colon, but who knows. As far as the TiO2, it was used in the coloring of the capsule and not for any other reason, which seems a pointless and silly purpose.
"In order to save the village organ, we had to destroy remove it" -- Doctor's Prescriber's proverb. 
 

pb4
Elite Member


Date Joined Feb 2004
Total Posts : 17877
   Posted 5/19/2012 12:09 PM (GMT -6)   
Far as I know, all the "ols" start with a "T"= "tol"
bee propolis caps 500mg one cap twice/day
omegas 369 caps one cap twice/day
probiotics 10 billion cfu once/day
vitamins C-calcium ascorbate (easy on the gut) and vitamin A each once/day
Prodiem fibre supplement one cap before bed
I've also altered my diet (no junky stuff at all, processed, fast-foods, refined sugars, ect) and exercise regularly.
I went from 30+ bloody BM's/day with lots of lower back pain to an average of 5/day no bleeding no back pain and completely formed stools, still have severe urgency issues.
~~~~~~~~My bum is broken....there's a big crack down the middle of it! LOL :)~~~~~~~~

FromChaos
Regular Member


Date Joined Aug 2011
Total Posts : 73
   Posted 5/20/2012 9:38 AM (GMT -6)   
I am not so sure it causes IBD but for me it certainly aggravates my condition.
Sucralose seems to be the worse. It pretty toxic from what I have read. I also stay away from the sugar alcohols, that has immeadiate effect on my
colon.
UC left sided since 1996
Asacol 400 mg 12 tabs daily

probiotics iron fish oil L-Glutamine
no soy no artificial sweetners
low carb

"stay positive and love your life"
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