SSRI (Celexa) and UC

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ActiveUCer
Veteran Member


Date Joined Jul 2012
Total Posts : 1685
   Posted 8/18/2012 10:16 PM (GMT -6)   
I was browsing for some information tonight and just discovered that SSRI's can cause gastrointestinal bleeding? In fact, colitis is listed as one of the side effects of Celexa (a drug that I take). It is listed as a rare side-effect though.

Does anybody know any other information about this? I couldn't find out additional information about what type of colitis, how severe the colitis might be, how long the colitis would take to set in when starting the drug, etc.

I did a search of the forum and found a couple of threads about people starting Celexa and possibly making their UC a bit worse...but just wondered if anyone else had more info.

UC2010
Regular Member


Date Joined Jul 2010
Total Posts : 39
   Posted 8/19/2012 5:23 PM (GMT -6)   
I started Celexa about 6 weeks ago along with Xanax as needed for General Anxiety. I haven't noticed any GI related side effects. My GI suggested I should go on an SSRI so after meeting with my primary doctor he agreed and suggested Celexa.
23 y/o Male
Jan. 28, 2010: Colonoscopy - DX w/ Moderate/Severe UC (Pancolitis)
July 30, 2010: Sigmoidoscope - Lialda not controlling UC
FLARES: Dec. 2009 to Feb., 2010, July 1 to Sept. 25, 2010
CURRENT MEDS: Lialda 1x per day, Humira (began 8/12/10)
PAST MEDS: Lialda 4x per day, Prednisone 60mg to control flare

suebear
Forum Moderator


Date Joined Feb 2006
Total Posts : 5419
   Posted 8/19/2012 6:50 PM (GMT -6)   
I took Celexa for 4 years after my jpouch surgery. I never had bleeding as a side effect.

Sue
Moderator, Ostomy Forum

Ulcerative Colitis- 1987-2001
2001- opted for j-pouch surgery

InSoFla
Veteran Member


Date Joined Jan 2011
Total Posts : 4679
   Posted 8/19/2012 6:50 PM (GMT -6)   
It's very possible.
I posted some time ago a query about Cymbalta having side effects of UC, rare too, but nevertheless a possibility (of course not one that the doctors disclose).
 
 
Let us know what you find out.
Rx meds didn't help me. But 4.5 mg LDN +Paleo diet +supplements=REMISSION.Protein shakes w/almond milk,Maca powder,L-Glutamine,D-Ribose,chia seeds.VSL#3,K2,VIt. D3,slippery elm bark powder.For more info,my protocol is the 11th post at this link: http://www.healingwell.com/community/default.aspx?f=38&m=1666318
If you have any questions, you can find my email address at my profile.

ActiveUCer
Veteran Member


Date Joined Jul 2012
Total Posts : 1685
   Posted 8/19/2012 9:36 PM (GMT -6)   
Thanks for the links to the threads. Unfortunately I did not find out any additional outside information to share.

InSoFla
Veteran Member


Date Joined Jan 2011
Total Posts : 4679
   Posted 8/20/2012 7:11 AM (GMT -6)   
 
My pleasure.
What do you think is the connection?
Rx meds didn't help me. But 4.5 mg LDN +Paleo diet +supplements=REMISSION.Protein shakes w/almond milk,Maca powder,L-Glutamine,D-Ribose,chia seeds.VSL#3,K2,VIt. D3,slippery elm bark powder.For more info,my protocol is the 11th post at this link: http://www.healingwell.com/community/default.aspx?f=38&m=1666318
If you have any questions, you can find my email address at my profile.

ActiveUCer
Veteran Member


Date Joined Jul 2012
Total Posts : 1685
   Posted 8/20/2012 9:28 AM (GMT -6)   
Well, the "connection" was merely the fact that colitis is listed as a possible side effect of celexa. I had never heard that before. general GI bleeding is also listed as a side effect, but it generally refers to upper GI bleeding. I started Celexa about 1.5 years before I was dx'ed with UC so I was just looking at potential influences/ causes. Both side effects are listed as very rare though.

I think I read somewhere that serotonin had some role to play in the intestines, but I wasn't paying too much attention.
UC sufferer diagnosed July 2011
One never ending flare
enemas, suppositories, Asacol, Lialda, and Colazal = worthless for me
Imuran/Azathioprine = bad liver and pancreas values
Remicade = First dose was a success but subsequent doses were useless
Prednisone = sitting at 40mgs. Still symptomatic :(
Paleo Diet = hospitalized with first flare while on Paleo

Step 1 of 3 scheduled end of Augus

bearmama
Regular Member


Date Joined Oct 2011
Total Posts : 20
   Posted 8/20/2012 9:43 AM (GMT -6)   
There has been some evidence that Wellbutrin can HELP UC--it is a TNF inhibitor like Remicade, Humira. Maybe you could switch and see what happens. There have even been studies on it but nothing definitive yet.
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