Histamine Intolerance

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garylouisville
Veteran Member


Date Joined Aug 2012
Total Posts : 6607
   Posted 11/16/2012 3:14 PM (GMT -6)   
Does anyone know anything about this? Recently I have been trying to figure out why I have such a bad reaction to Cheddar Cheese, high amounts of Orange Juice, and recently Pizza Hut Pizza. I have had a problem since UC day one regarding cheddar cheese, too much OJ and fruits (especially very ripe fruits), and have only recently(in the last few months) had problems with pizza. I also had a very bad reaction to the probiotic Florastor, which is a yeast and also has a small amount of lactose. I was believing my problem to be a reaction to casein since I have eaten regular amounts of lactose with no real problems. While researching a possible connection to the casein in cheeses I have come accross some very interesting information. Apparently people who have a problem with cheeses fall into 3 categories:
 
1. lactose intolerance
 
2. casein intolerance
 
3. amine intolerance, which is very closely related to histamine intolerance
 
If you are lactose inolerant then many different dairies will bother you. In my case, I tolerate many items containing lactose and have taken lactaid with cheddar cheeses, only to still have major problems. Cheddar cheese and other aged cheeses tend to have very little lactose in them.
 
If you have a casein intolerance you generally have a problem with all cheeses since all cheeses tend to have a fair amount of casein in them. I have tolerated other cheeses with no problems.
 
Now comes the interesting part. An amine or histamine intolerance will be more prevelant in aged items like some cheeses (cheddar for one), pizza (because of tomatoes and cheese), aged fruits and fruit juices (such as OJ), and yeasts (like in Florastor and foods high in yeast). Histamines are also involved in stress and I had a high amount of stress at my UC onset. Something in my brain is saying, "Bingo!".  There is actually a low histamine diet because there are histamines in foods, obviously some more than others. There are two main enzymes in your body which help break down histamine in foods. One is called diamine oxidase. It has been found that many of those who have UC have lower amounts of diamine oxidase in their bodies and has even been found that a genetic problem can be responsible for this. There are other allergic symptoms that can happen to you if you have a histamine problem. I have also read studies where some treat their UC with antihistimines with limited success but I have come accross a supplement of diamine oxidase you can buy to break down the histamines and the reviews seem to tout them much better than taking antihistamines and you can supposedly eat the foods you want as long as you take this enzyme at the same time. This may actually be the problem in some who are doing certain diets or think they have a gluten intolerance or candida problem. I would appreciate any comments or knowledge.
 
 
Asacol 400mgs 2 pillsX4; VSL#3 112.5mgs 2 pillsX4; DGL 400mgs 2 pillsX3; Monolaurin 300mgs 2 pillsX3; Vitamin D 5000 ius 1 pillX2, Thorne SF722 10pills/day, garlic 3 pills/day

Discontinued: Prescription - Glycopyrrolate; Natural - peppermint oil, Inflaguard (Boswellia), Pepto Bismol, Omega 3 fish oil, Imodium, Beano, Zymactive, Renew Life Probiotic 80 billion, Florastor, Slippery Elm

Post Edited (garylouisville) : 11/16/2012 1:19:48 PM (GMT-7)


DBwithUC
Veteran Member


Date Joined Feb 2011
Total Posts : 1612
   Posted 12/10/2012 10:22 AM (GMT -6)   
what brand are you using?
11/08: ischemic colitis and scope perf colon. 12cm colon/ileocecal resected. IV antib:sepsis.
01/10: Dx: Mod. UC pancolitis. Rx: Lialda 3x.
02/11: Major flare w/antib:sinus. Rx: 40mg Pred taper. 6mp.
07/11: Histol remiss rt/trans; worse sigmoid. Rx: Rowasa & hydrocort
---
Curr: 3-6 loose stool w/ blood, limited urgency: Lialda, 10mg Pred (dependent), sf-Rowasa, VSL DS, Vit-D/C, Omg3

GutsZilla
Regular Member


Date Joined Dec 2012
Total Posts : 64
   Posted 12/10/2012 12:49 PM (GMT -6)   
Interesting tidbits about histamine intolerance that may help you are here: http://thepowerofpoo.blogspot.com.au/p/my-story.html

garylouisville
Veteran Member


Date Joined Aug 2012
Total Posts : 6607
   Posted 12/10/2012 1:18 PM (GMT -6)   
I am taking Swanson DAO. Histame is another one but appears to have other ingredients in it along with the diamine oxidase enzyme. This makes the Histame a little more expensive as the Swanson version has the enzyme only.
Asacol 400mgs 2 pillsX4; VSL#3 112.5mgs 1 pillX4; DGL 400mgs 2 pillsX3; Monolaurin 300mgs 2 pillsX3; Vitamin D 5000 ius 1 pillX2; Thorne SF722 5pillsX3; garlicin 1 pill X 2; B6 1/day; diamine oxidase meals

Discont: Robinul; Natural - peppermint oil, Inflaguard (Boswellia), Pepto Bismol, Omega 3 fish oil, Imodium, Beano, Zymactive, Renew Life Probiotic 80 billion, Florastor, Slippery Elm

DBwithUC
Veteran Member


Date Joined Feb 2011
Total Posts : 1612
   Posted 12/10/2012 2:26 PM (GMT -6)   
worth a try. I seem to have some loose stool/D symptoms that persist no matter what.
11/08: ischemic colitis and scope perf colon. 12cm colon/ileocecal resected. IV antib:sepsis.
01/10: Dx: Mod. UC pancolitis. Rx: Lialda 3x.
02/11: Major flare w/antib:sinus. Rx: 40mg Pred taper. 6mp.
07/11: Histol remiss rt/trans; worse sigmoid. Rx: Rowasa & hydrocort
---
Curr: 3-6 loose stool w/ blood, limited urgency: Lialda, 10mg Pred (dependent), sf-Rowasa, VSL DS, Vit-D/C, Omg3

garylouisville
Veteran Member


Date Joined Aug 2012
Total Posts : 6607
   Posted 12/10/2012 2:40 PM (GMT -6)   
The enzyme is supposedly very safe with no side effects. I saw a video by a doctor. Basically you want to have just as much or slightly more DAO in your body than histamine. Of course that is about impossible to calculate. The doctor said that if you take more DAO than you have histamine it does not provide you any more benefit but that it is basically a protein and you could theoretically take 10,000 bottles of it a day and it would not harm you. Supposedly this works for ingested histamine only and not other forms of histamines which are allergy or otherwise related. I just recently bought four bottles of 30 pills for $15 per bottle. I was able to eat all of my problem foods with absolutely no problem whereas before I would be running to the bathroom about 20 times in the next few hours with bloody diarrhea. I'm hoping it helps my UC other than just helping me with my problem foods but so far there isn't any evidence that that is happening other than having a little bit better than normal day even after eating a problem food. So, there is a little hope in it all.
Asacol 400mgs 2 pillsX4; VSL#3 112.5mgs 1 pillX4; DGL 400mgs 2 pillsX3; Monolaurin 300mgs 2 pillsX3; Vitamin D 5000 ius 1 pillX2; Thorne SF722 5pillsX3; garlicin 1 pill X 2; B6 1/day; diamine oxidase meals

Discont: Robinul; Natural - peppermint oil, Inflaguard (Boswellia), Pepto Bismol, Omega 3 fish oil, Imodium, Beano, Zymactive, Renew Life Probiotic 80 billion, Florastor, Slippery Elm

Petah
Veteran Member


Date Joined Nov 2012
Total Posts : 995
   Posted 9/2/2013 8:24 AM (GMT -6)   
garylouisville said...
The enzyme is supposedly very safe with no side effects. I saw a video by a doctor. Basically you want to have just as much or slightly more DAO in your body than histamine. Of course that is about impossible to calculate. The doctor said that if you take more DAO than you have histamine it does not provide you any more benefit but that it is basically a protein and you could theoretically take 10,000 bottles of it a day and it would not harm you. Supposedly this works for ingested histamine only and not other forms of histamines which are allergy or otherwise related. I just recently bought four bottles of 30 pills for $15 per bottle. I was able to eat all of my problem foods with absolutely no problem whereas before I would be running to the bathroom about 20 times in the next few hours with bloody diarrhea. I'm hoping it helps my UC other than just helping me with my problem foods but so far there isn't any evidence that that is happening other than having a little bit better than normal day even after eating a problem food. So, there is a little hope in it all.
Gary did ypu
Just guess you had a histamine intolerance? I've read it hard to pinpoint?

garylouisville
Veteran Member


Date Joined Aug 2012
Total Posts : 6607
   Posted 9/2/2013 9:00 AM (GMT -6)   
I self diagnosed if that's what you mean. It wasn't really a guess. It was more like a very very educated guess. Medical professionals were not involved. There were several different things seemingly unrelated which made my UC much worse. They were so different I figured there must be something they all had in common. After much research I discovered that there was only one thing they all had in common - they were either high in histamine or somehow reacted with your body to increase histamine. That was the absolutely only thing that all of these different things had in common. Since taking the DAO I can now eat high histamine foods with no problem.
Asacol 800mgs 1 pillsX3; VSL#3 112.5mgs 1 pillX2; Prescrip Assist Probiotic 1 pill X 2;Vitamin D3 5000 ius 1 pillX2;Bentyl;DAO;Folic acid

Discontinued: Robinul; Natural - peppermint oil, Inflaguard (Boswellia), Pepto Bismol, Omega 3 fish oil, Imodium, Beano, Lactaid;Zymactive, Renew Life Probiotic 80 billion, Florastor, DGL, Monolaurin, slippery elm;black cherry concentrate
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