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Levi
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Date Joined Nov 2009
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   Posted 2/13/2013 2:45 PM (GMT -6)   
Well, I told myself and told myself I would not post about this even if I thought it was helping me, but I have changed my mind. I started reading about how DMSO is a proven anti-inflammatory for certain conditions. I read a couple of testimonials about how it has helped Crohn's patients. Most said that it would only help the pain and not the underlying inflammation itself. I decided to give it a try anyway.
 
I promised myself if I thought it worked I would at least wait a little while before posting about it. I have taken one teaspoon of the 99.98 pc pure DMSO every single day since October 22nd. I rub one teaspoon on my abdomen and let it absorb thru the skin and into my bloostream. I stay there for 15-20 minutes most days. In October I was coming off a Pred taper and still had a good amount of blood and loose stools up to the point I was off Pred. In the past almost four months my blood has decreased to almost nothing, maybe a small stringly piece at the end of the stool or beginning, especially if I haven't done Rowasa the previous night and have a really firm bowel movement.
 
The most dramatic (and immediate change) was the form. It firmed up instantly. It was amazing to go to the bathroom, wipe with the toilet paper, and see nothing on it. I would say 80% (at least) of my bowel movements I wipe absolutley nothing, the paper is completley clear except for maybe some Rowasa detritus early in the morning. I have never had such good firm bowel movements, even in my six month remission a couple of years ago when I had a scope that only showed internal hemmies. I don't know if it's the DMSO, I hope it is because it *seems* to be working for me. Ninety percent of the time I go in the morning and a few hours after lunch. The last two days I've only been once in the morning-something that is very very very rare for me.
 
That's about it. Correlation doesn't prove causality, but if it did, the DMSO would be proven effective for IBD, at least in my case.

Old Mike
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Date Joined Jan 2007
Total Posts : 2481
   Posted 2/13/2013 2:51 PM (GMT -6)   
Yep,I did this years ago but had to stop due to the stench,I believe the newer
DMSO is more refined and you dont get the sulfur smell so much or not at all.
It comes out of your skin,my wife could not stand it.
Do you smell any sulfur odors from your skin.
May revisit.
Old Mike

Levi
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Date Joined Nov 2009
Total Posts : 1553
   Posted 2/13/2013 2:57 PM (GMT -6)   
Yeah, the new more refined compound is a LOT better than the testimonials I have read, though I still smell it emanating up through my mouth though. I grilled some hamburgers in late October (the first week I was on it) after a 'treatment' and thought they must have been raw or something and was really worried how it would affect my CD. A few days later I realized what it was, just DMSO aftertaste. The fiance also would not kiss me due to 'sour milk breath'. For whatever reason though, the external smell is completely gone (well, I'm not getting complaints for a few months.) The internal is 90% gone, so much so that I sometimes try to make sure I can still taste it a little during the treatment as I guess it gives me a little comfort that it's still working.

Post Edited (Levi) : 2/13/2013 1:02:05 PM (GMT-7)


Old Mike
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Date Joined Jan 2007
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   Posted 2/13/2013 3:02 PM (GMT -6)   
The smell is due to oxidized DMSO/impurities, it is the oxidized sulfur metabolites that smell. It would seem you now have much less oxidation going on.
Do you take it straight or dilute with water before swallowing.
Thanks
Old Mike

killcolitis
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Date Joined Dec 2009
Total Posts : 2396
   Posted 2/13/2013 3:06 PM (GMT -6)   
Congrats Levi-it's not something I've really looked into due to safety issues but I'm glad it's working for you. Which meds are you on now?

Levi
Veteran Member


Date Joined Nov 2009
Total Posts : 1553
   Posted 2/13/2013 3:09 PM (GMT -6)   
Hmm...why might I have less oxidation going on? My body getting used to it and it becoming less effective? Less oxidation of free radicals or something else?
 
Edit: oh I read again you said it's the sulfur being oxidized...shouldn't the same amount be oxidized everytime then, if I'm taking the same amount? Hopefully it's not becoming slowly less effective.

I take it straight, no dilution-but not orally. I rub it right on my belly, one teaspoon, maybe a little more. I put it on it probably four different applications over the first half of the 20 minutes and let it soak in the last ten. I clean the belly very well and three fingers on my left hand. You have to keep them clean though because that stuff will itch like nobody's business. The first day I didn't know how badly it would itch and I had started reading a paperback, so both hands were possibly 'contaminated'. I didn't want to start over so I endured it. I was thrashing and bucking like The Exorcist by the end. From then on, it's iPad in my right hand, and just sorta keep rubbing every so often with my left hand, middle, ring, and pinky fingers.

Post Edited (Levi) : 2/13/2013 1:12:33 PM (GMT-7)


Levi
Veteran Member


Date Joined Nov 2009
Total Posts : 1553
   Posted 2/13/2013 3:10 PM (GMT -6)   
KC-Pentasa, VSL#3DS, Rowasa, & 6mp and supplements-all of which I've been on since at least the end of 2011.
29 years old
Diagnosed 2009 proctosigmoiditis, 2010 Crohn's colitis, 2011 ileocolitis
Symptoms since 10.2007
Pentasa, four grams/day, 6mp 50 mg/day
Rowasa enema, 3 grams every other night
VSL#3 DS one packet/day and VSL#3 yogurt
Turmeric, digestive enzymes, boswellia, propolis, cat's claw, l-glutamine, fish oil, vitamin D, kefir, blueberries
Liver-Milk Thistle; Heart-Hawthorn, sometimes

Old Mike
Veteran Member


Date Joined Jan 2007
Total Posts : 2481
   Posted 2/13/2013 3:17 PM (GMT -6)   
What I mean is that,your body is not in a high oxidizing state,the DMSO
has quenched what was going on and it would seem you are healing.
That is what the lower level of smell means to me,along
with your improved symptoms.
Old Mike

Levi
Veteran Member


Date Joined Nov 2009
Total Posts : 1553
   Posted 2/13/2013 3:25 PM (GMT -6)   
Awesome, yes that would definitley go along with my improving symptoms.

I went back and looked at my excel file (where I track food and bowel movemnts etc-never has so much crap been documented so meticulously :)), and to the best of my recollection the smell waned gradually around the Thanksgiving to Christmas time period where it reached it's current minimal level. Although stool form improved instantly, bleeding did not. It's improvment, did however, correspond pretty well with the decrease in smell and odor.

Thanks for helping with that correlation!
29 years old
Diagnosed 2009 proctosigmoiditis, 2010 Crohn's colitis, 2011 ileocolitis
Symptoms since 10.2007
Pentasa, four grams/day, 6mp 50 mg/day
Rowasa enema, 3 grams every other night
VSL#3 DS one packet/day and VSL#3 yogurt
Turmeric, digestive enzymes, boswellia, propolis, cat's claw, l-glutamine, fish oil, vitamin D, kefir, blueberries
Liver-Milk Thistle; Heart-Hawthorn, sometimes

hateuc
Veteran Member


Date Joined Jun 2010
Total Posts : 1762
   Posted 2/13/2013 3:34 PM (GMT -6)   
That is great Levi! I remember you mentioning this once before, but you were not ready to officially declair it. Hope it continues to work great for you!!


B
UC diagnosed in 2010 but had prob. in 2009
2 Lialda/day Rowasa nightly, periodic anucort supp, starting Cortifoam 8/12
VSL#3, slippery elm
Metamucil wafers

Somedude
Veteran Member


Date Joined Jul 2011
Total Posts : 3392
   Posted 2/13/2013 3:41 PM (GMT -6)   
can you link to the actual product you are using, so I may check it out and buy it.
DX Ulcerative Colitis (pancolitis) - May 2011. (Remicade Max/6 wks, LDN, SCD, vitam.)

"Life is like a box of chocolates; you never know what you' gonna get. " by Forrest Gump

IamCurious
Veteran Member


Date Joined Jan 2010
Total Posts : 2224
   Posted 2/13/2013 3:43 PM (GMT -6)   
I tried a 70 percent solution of DMSO because there were reports that it cures hemorrhoids. It did not work for me because it turned out that I did not have hemorrhoids at all but a perianal abscess.
Male/61 DX IBD in Feb08. No meds, allergic to Mesalamine. Remission since Mar10. Powdered psyllium seed mixed with VSL3 is very helpful. Food journal instead of SCD or Paleo.

Lots of fruit & vegetables (but no plums or cruciferous), No Gluten, no soda, no HFCS, no xylitol or sorbitol, no trans fat, no shellfish, few processed foods, no carrageenan.
Probiotics, fish oil, multivitamin, extra D3, K2, E complex, phos choline, magnesium, boswellia, curcumin, DGL, glutamine.
Nature created all of the locks, therefore Nature has all of the keys

Levi
Veteran Member


Date Joined Nov 2009
Total Posts : 1553
   Posted 2/13/2013 3:52 PM (GMT -6)   
hateuc said...
Hope it continues to work great for you!!
Thanks. From your lips to God's ears!
 
Somedude, I get it from here, the 99.98 pc pure. It says to dilute I think, I don't. The first week it REALLY irritated my skin. Also got to much on a 3/4 inch x 3 inch or so swathe of my belly and it tore it up-red and ugly for a week or so. Seems my skin has adapted if you will though and don't have irritation problems.
 
 
I just went in my mother's office (I work for BOTH my parents cry haha) anyway, and told her about the correlation Old Mike posited about the smell and healing. She said don't you remember a couple of months ago I kept telling you how great your complexion looked and you kep saying, jokingly, "do I have a self esteem problem I don't know about you are tyring to build up for some reason?" I honestly didn't know what she was talking about or why she was saying it, I haven't had acne since high school, but I wonder if it has something to do with the medicine. I don't want to go on too many tangents-I think humans are by nature prone to look for patterns and connections...but it is slightly odd.

Old Mike
Veteran Member


Date Joined Jan 2007
Total Posts : 2481
   Posted 2/13/2013 4:03 PM (GMT -6)   
The smell may not totally go. Your body is always oxidizing many compounds,but in IBD there is increased oxidation going on. You may have noticed I am always talking about,ROS, superoxide,
peroxynitrates, iron,fenton reaction, antioxidants,and many others.
And yes it does irritate the skin, and possibly what is below it.
I may have taken it internally,in addition to on the skin, so long ago can't remember.
DMSO may not cure the underlying cause of IBD,but then again who knows.

Old Mike

Post Edited (Old Mike) : 2/13/2013 2:36:26 PM (GMT-7)


NatWell
Regular Member


Date Joined Dec 2010
Total Posts : 101
   Posted 3/19/2013 11:20 AM (GMT -6)   
The oxidation issue from all of my research has something to do with oxygen being OUTSIDE the cell instead of inside. This is why people with UC cannot use H202. The smell may be also getting rid of the excess which is contributing to free radicals that are oxygen driven. Also, this H202 story always seems weird to me because of course oxygen heals, but not in our case. Cellfood is a product developed with the H202 concept, just less free radical throw-off, but if it is true that it brings nutrients and oxygen into the cell, then why is this and H202 not good? I have also read that because the oxygen is outside the cell with UC that it turns into H202. Mmmm - anyone else looked into this?

NatWell
Regular Member


Date Joined Dec 2010
Total Posts : 101
   Posted 3/19/2013 11:21 AM (GMT -6)   
Some recent research also says there may be something wrong with the spleens of people with UC
First pancolitis flare Nov. 10'. Very up and down, never quite the same. TSO keeps me out of the hospital. Went off TSO, back in the hospital, back on TSO, out of the hospital. Resistant to ALL meds. 40mg Pred. Currently 10-20 BBM's/day. Just started Fecal Transplant at home 1/19/2012 using mother as donor… VERY HOPEFUL! Protocol- 1/day 10days and go from there. -Too many supplements to list-

garylouisville
Veteran Member


Date Joined Aug 2012
Total Posts : 6363
   Posted 3/19/2013 1:05 PM (GMT -6)   
What if you don't have a spleen?
Asacol 400mgs 2 pillsX3; VSL#3 112.5mgs 1 pillX3; Vitamin D3 5000 ius 1 pillX2;Bentyl & Swanson DAO with meals;black cherry concentrate

Discontinued: Robinul; Natural - peppermint oil, Inflaguard (Boswellia), Pepto Bismol, Omega 3 fish oil, Imodium, Beano, Zymactive, Renew Life Probiotic 80 billion, Florastor, DGL, Monolaurin, slippery elm

Malkavian
Veteran Member


Date Joined Mar 2009
Total Posts : 1439
   Posted 3/19/2013 3:40 PM (GMT -6)   
DMSO is a laboratory solvent and it's actually somewhat toxic and can allow toxic substances on your skin to enter the body (which is why we wear gloves when handling anything solved in it). I doubt the way you're taking it is actually delivering the chemical to your gut-you might as well rub it on your nose since the only way you're going to get it from your skin to your gut is through the bloodstream.

I also hope you are keeping it in a flammables cabinet of some sort as it explodes below the temperature of boiling water.
Heather, 25 year old immunology Ph.D candidate
Ulcerative colitis from rectum to mid transverse colon, diagnosed 3/6/2009, symptoms for 2 years beforehand
In remission for ~3 years
Currently on lialda 4x/day, azithioprine 150 mg/day, vitamins
Allergies: penicillin, sulfa, bee stings, environmental (especially ragweed!), singulaire and otc meds daily

Levi
Veteran Member


Date Joined Nov 2009
Total Posts : 1553
   Posted 3/19/2013 4:05 PM (GMT -6)   
I don't put it on my abdomen because it's proximal to the colon-it just happens to be the most natural position for my arms to be to rub it in. I put it on the top couple of inches of my leg as well.

If I put it on my nose it would probably burn the sensitive flesh and I would look like Rudolph
29 years old
Diagnosed 2009 proctosigmoiditis, 2010 Crohn's colitis, 2011 ileocolitis
Symptoms since 10.2007
Pentasa, four grams/day, 6mp 50 mg/day
Rowasa enema, 3 grams every other night
VSL#3 DS one packet/day and VSL#3 yogurt
Turmeric, digestive enzymes, boswellia, propolis, cat's claw, l-glutamine, fish oil, vitamin D, kefir, blueberries
Liver-Milk Thistle; Heart-Hawthorn, sometimes

Levi
Veteran Member


Date Joined Nov 2009
Total Posts : 1553
   Posted 3/20/2013 6:34 AM (GMT -6)   
Reading the post about the laboratory usage of DMSO triggered a dormant memory. I've been following the development of a stem cell for Crohn's called Prochymal. It is being tested on moderate to severe cases that have failed at least TWO biologics. Prochymal is showing very promising results. On of the trials had to be cancelled and redone though because of the way the stem cells were stored in DMSO even the placebo group was receiving DMSO. The results were that Prochymal didn't show any statically significant healing in the stem cell patients over those picked to receive the placebo. Ostensibly, the DMSO was having a healing affect on the placebo patients as well. The company's stocked actually tanked as a result of patients responding to the placebo/DMSO.
29 years old
Diagnosed 2009 proctosigmoiditis, 2010 Crohn's colitis, 2011 ileocolitis
Symptoms since 10.2007
Pentasa, four grams/day, 6mp 50 mg/day
Rowasa enema, 3 grams every other night
VSL#3 DS one packet/day and VSL#3 yogurt
Turmeric, digestive enzymes, boswellia, propolis, cat's claw, l-glutamine, fish oil, vitamin D, kefir, blueberries
Liver-Milk Thistle; Heart-Hawthorn, sometimes

DanthaMan
Regular Member


Date Joined May 2005
Total Posts : 467
   Posted 3/26/2013 10:08 AM (GMT -6)   
okay I have done DMSO in the past and this thread reminded me of it. I just started trying to do sauted spinach and the next day like clock work I am going to that bathroom way more. I thought it was from the oxlates but having read that most of them are destroyed in the cooking process I began looking elsewhere.

www.livestrong.com/article/497467-nutritional-value-of-fresh-vs-cooked-spinach/

You will see that there is way more iron once its cooked. I just started DMSO yesterday and did a spinach smoothie this morning while also applying the DMSO. I want to ease back into cooking the spinach.

This is why I think DMSO will work:
www.newtreatments.org/ga.php?linkid=60

davea0511
New Member


Date Joined Aug 2014
Total Posts : 1
   Posted 8/26/2014 10:35 PM (GMT -6)   
Malkavian said...
DMSO is a laboratory solvent and it's actually somewhat toxic and can allow toxic substances on your skin to enter the body (which is why we wear gloves when handling anything solved in it). I doubt the way you're taking it is actually delivering the chemical to your gut-you might as well rub it on your nose since the only way you're going to get it from your skin to your gut is through the bloodstream.

I also hope you are keeping it in a flammables cabinet of some sort as it explodes below the temperature of boiling water.


I know this is a necropost, apologies, but it would really be unfortunate if someone decided due to faulty information to not try something that could be very beneficial.

DMSO is indeed a solvent, assuredly used in laboratories and other places. So is water. Any liquid that things dissolve in may also be considered "a solvent".

It does *not* even remotely explode below 100°C (212°F), boiling point of water. It's auto-ignition point (where it might explode) is at 215°C (419°F). It's flash point is 89°C (192.2°F), but did you know the flash point for whiskey is 26 °C (79 °F) and for wine it's between 97°F and 126°F? Although DMSO is flammable (as is your hair and most things in your house), it isn't at room temperature and it will put out fire at up to 197°F just as water will when you pour it on fire. Extremely safe in that regard.

Consider that the flash point of that nail polish in your medicine cabinet is -4°C (24°F), ie - even in your fridge nail polish can explode if exposed to an ignition source, and you keep that in closed cabinets ... thousands of people foolishly do so with the cap off, but you don't hear about those same people having nail-polish related explosions.

Calling it toxic is like calling dihydrogen oxide (H2O) bad because water is found in all liquid poisons.

DMSO in and of itself is surprisingly non-toxic and entirely bio-compatible. The only study which showed a negative effect was it was altering the corneas of mice when they were force fed daily amounts exceeding their own body weight over a period of many weeks. No human has ever consumed so much, nonetheless some practitioners warn that it can adversely affect eyesight, whereas many at early cataract onset claim DMSO eyedrops cleared their cataracts up. Note that the rat's vision eventually returned to normal after use was discontinued.

Like anything, too much is probably bad, but that also depends on the condition you're treating. I believe you can handle more with greater illness.

It *IS* a chemical hypodermic needle, so you must be extremely careful to have extremely clean hands and washed skin wherever it touches. Only apply it with biocompatible things (like a cotton cloth, perhaps washed with baking soda instead of detergent and well rinsed), diluted only with purified water, and combined only with substances that you can consume in large quantities without adverse side effects. Anything with a molecular weight above 1000 will not be carried with it into the blood stream (it will not transport bacteria or viruses).

You will smell like garlic, body odor and breath for up to 2-3 days. Less so if you use small amounts (less than 1ml), you might loose the body odor but will still have the breath - nothing to do about that ... it's coming from your lungs so brushing teeth won't help much. Many advocates claim that after a while the odor goes away ... having something to do with your body gaining the ability to take care of the resulting sulfuric metabolites, which may be improved as your body looses toxicity due to DMSO use. Some say combining with D-limonene (citrus essential oil) helps with smell. Other possible remedies include parsley, Chlorella, fenugreek sprouts, and chlorophyll and external use of urea. Some claim that if you have toxicities the smell will be much worse (not just garlic smell) for the first while until the toxins are removed.

It will cause you to absorb everything for up to 6 hours so lay off any lotions, don't touch poisons, don't use soaps at that time. Do not take it with any drugs as it may enhance any negative side effects. Wear natural fibers during use, not polyester.

No residual accumulation of DMSO has occurred in man or lower animals who have received DMSO treatment for protracted periods of time.

Recommended administration: DMSO applied to the skin is administered in 50% concentration above the neck and 70% below the shoulders. It may be administered multiple times throughout the day.
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