Cirrhosis/ fatty liver

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Petah
Veteran Member


Date Joined Nov 2012
Total Posts : 1005
   Posted 3/19/2013 11:46 PM (GMT -7)   
What are the chances of getting this from this disease? I just found out its possible

Teddtlove
Veteran Member


Date Joined Jan 2013
Total Posts : 1027
   Posted 3/20/2013 1:01 AM (GMT -7)   
I have fatty liver but it could be because I am overweight. My mom who does not have UC also has fatty liver.
30 female. Sherrie, 2007 diagnosed with UC, also have Hypothyroidism, Leukocytosis, Agoraphobia, Bipolar tendencies, Panic disorder, Acid reflux, Lactose intolerance, Eczema, Migraines, Degenerative disk, Hypertension, and Anemia.
Lialda, Canasa, Hyoscyamine sulfa, digestive ad lactose defense, lyrica, Lomotil , klor-con20, VSL 3DS, Rainbow light, bit D Pred 10 mg, started Humira 12/31

deltaforce
Veteran Member


Date Joined Jun 2010
Total Posts : 1995
   Posted 3/20/2013 8:59 AM (GMT -7)   
I would not worry about it, UNLESS I am taxing liver too much. For e.g. I take medications those are primarily metabolized by the liver and affect liver enzymes. In such case, if I am going out every weekend to get drunk then I would worry.

Since I started Imuran, I gave up ALL alcohol.

I too have fatty liver from last year's long Pred course. Haven't performed liver panel in last 5 months, so its time for it.
Diagnosed March 2007 with left sided UC.
Currently on daily dose of,
Colazal 9 caps, Imuran, 200mg, Vit. B12, 1mg, Multivitamin, 1 tablet, Fish oil 2400mg , Vit D 2000 IU, Benebiotics 2caps

Verapamil 320mg, Nortryptyline 20mg for migraine, Migraine episode now at least 4X a month,
Nabumetone 750mg as an abortive, so far so good with GI side effects.

Red_34
Forum Moderator


Date Joined Apr 2004
Total Posts : 22145
   Posted 3/20/2013 9:14 AM (GMT -7)   
There are a lot things possible with this disease but it doesn't mean it will happen. You need to stop looking at the what ifs or you're going to drive yourself crazy.
SHERRY
Moderator-Allergies/Asthma, Alzheimer's, IBS, Co-moderator-UC
Diagnosed Left sided UC '92 - meds: Colazal, Remicade (6mp discontinued due to neuropathy)*Unable to tolerate ALL mesalamines*, IBS, Diverticuliar Disease, Fibro, Sacroiilitis, Raynauds, OA, PA, Rosacea, Psoriasis, Dry Eye and allergies controlled by Zyrtec and Singular

quincy
Elite Member


Date Joined May 2003
Total Posts : 25828
   Posted 3/20/2013 10:04 AM (GMT -7)   
ditto Sherry....we can do a comparison here and see that not all have the same extraintestinal issues. General complaints are similar, however.
You won't control what happens that's related to UC specifically...or what's autoimmune, etc.  Genetics rule, and you'll not control the triggers.
 
You can, however, note meds such as prednisone and its continued use....and hopefully avoid using it by maintaining and treating with meds that are less likely to cause more serious issues. I'll get on the 5ASA bandwagon for now...and hopefully you can remain on it.
 
q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

Post Edited (quincy) : 3/20/2013 10:08:31 AM (GMT-6)


Petah
Veteran Member


Date Joined Nov 2012
Total Posts : 1005
   Posted 3/20/2013 4:31 PM (GMT -7)   
I know Sherrie. It's so hard not to worry! :( hopefully good things will start happening soon.
Proctitis ??
Pentasa 1g Enema
Slippery elm powder/ Manuka Honey 20+ Active.
Kefir Yogurt.

deltaforce
Veteran Member


Date Joined Jun 2010
Total Posts : 1995
   Posted 3/20/2013 5:14 PM (GMT -7)   
Although I agree with Sherry, I always keep an eye on related conditions (so your worry is not worthless). Take this with a pinch of salt, I came across a scientific article that studied genome-wide association of IBD and it turns out, we are predisposed to ankylosing spondylitis and psoriasis. This is just a warning for us, so in case in future, you are the unlucky one, you know where to look for (in case your expert MD fails to figure out).
Diagnosed March 2007 with left sided UC.
Currently on daily dose of,
Colazal 9 caps, Imuran, 200mg, Vit. B12, 1mg, Multivitamin, 1 tablet, Fish oil 2400mg , Vit D 2000 IU, Benebiotics 2caps

Verapamil 320mg, Nortryptyline 20mg for migraine, Migraine episode now at least 4X a month,
Nabumetone 750mg as an abortive, so far so good with GI side effects.

bettylou
Regular Member


Date Joined May 2009
Total Posts : 118
   Posted 3/20/2013 5:33 PM (GMT -7)   
I ended up in hospital with liver problems on AZA. Not uncommon but plenty do fine on it.
Ulcerative Colitis: diagnosed as moderate pan-colitis August 2008.
Baby daughter born October 2010. Struggling to cope since.
Done Prednisolone a few times and have recently stopped Azathioprine due adverse liver reaction.
Lialda/Mezavant 4.8g/day; Salofalk enemas as needed.
Low carb diets all relieve symptoms, but cannot achieve remission.

Petah
Veteran Member


Date Joined Nov 2012
Total Posts : 1005
   Posted 3/20/2013 6:29 PM (GMT -7)   
Quincy you've had this for a long time, how's your liver held up?
Proctitis ??
Pentasa 1g Enema
Slippery elm powder/ Manuka Honey 20+ Active.
Kefir Yogurt.

Red_34
Forum Moderator


Date Joined Apr 2004
Total Posts : 22145
   Posted 3/20/2013 9:20 PM (GMT -7)   
I can't speak for Q but I'm also a long term Uc'er. I've had this for 21 years and my liver is just fine.

Delta, I always wondered about the psoriasis connection...in my case it's more what came first? The chicken or the egg...because I had psoriasis 5 years before I was diagnosed with Uc.
SHERRY
Moderator-Allergies/Asthma, Alzheimer's, IBS, Co-moderator-UC
Diagnosed Left sided UC '92 - meds: Colazal, Remicade (6mp discontinued due to neuropathy)*Unable to tolerate ALL mesalamines*, IBS, Diverticuliar Disease, Fibro, Sacroiilitis, Raynauds, OA, PA, Rosacea, Psoriasis, Dry Eye and allergies controlled by Zyrtec and Singular

quincy
Elite Member


Date Joined May 2003
Total Posts : 25828
   Posted 3/21/2013 12:52 PM (GMT -7)   
Petah...I have PBC (primary biliary cirrhosis), as recently decided by the docs based on the blood testing and some visuals from the MRCP.
I'm on ursodiol, and all my liver enzyme tests are perfect. They were quite elevated about 15 years ago, hence the thought I had PSC.

I refused to have the ERCP, was put on URSO and eventually had an MRCP.

Everything is fine meaning nothing is worse. I believe that my goal for keeping UC as quiet as possible is helpful in keeping all the other stuff quieter as well. But, I could be wrong...lol, at this point, all is good.

q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

deltaforce
Veteran Member


Date Joined Jun 2010
Total Posts : 1995
   Posted 3/22/2013 6:28 AM (GMT -7)   
@Red_32,
It is difficult to say what came first. So far the literature isn't specific about it but they do mention that you could have one autoimmune condition dormant when the other is flaring and the flaring one could be as a result of the dormant one. This current understanding is honestly freaking me out that, is my migraine result of some autoimmunity? If not, why the heck the medications that work with majority of migraneurs do not work for me? And/or, is there any other condition that is dormant at this moment I am unable to figure out?

The condition Quincy mentioned, PBC, could also be a result of UC. about 3.5% of UC sufferers show this extraintestinal manifestation. I wonder why Quincy refused ERCP, the literature states thats the best way to go (but I don't know the downsides, hence the question.)

http://www.ncbi.nlm.nih.gov/pubmed/23371321 is a very good overview of many extraintestinal manifestations. Let me know if anybody wants to read it, will upload somewhere.
Diagnosed March 2007 with left sided UC.
Currently on daily dose of,
Colazal 9 caps, Imuran, 200mg, Vit. B12, 1mg, Multivitamin, 1 tablet, Fish oil 2400mg , Vit D 2000 IU, Benebiotics 2caps

Verapamil 320mg, Nortryptyline 20mg for migraine, Migraine episode now at least 4X a month,
Nabumetone 750mg as an abortive, so far so good with GI side effects.

quincy
Elite Member


Date Joined May 2003
Total Posts : 25828
   Posted 3/22/2013 1:17 PM (GMT -7)   
Are you asking Red or me about why I refused the ERCP?

Out of the 3" stack of paper information on it that I got through a friend who has access to medical info, one page written by a doctor said that the definitive diagnostic tool of the ERCP isn't the best. As well, the side effects can also cause serious problems.

An ERCP can exacerbate a slow progressing early stage PSC into full blown activation. As well, it can cause pancreatitis, infection of the bile ducts..etc It's invasive.
It's not the only diagnostic tool.

My symptoms were only raised liver enzyme levels.

I wasn't wanting to deal with anything else for just a fishing expedition.

I was put on URSO anyway, enzyme levels dropped immediately.

The MRCP was in the process of being a diagnostic tool during that time (1998)...so in 2005 I finally had one.

PBC is considered autoimmune, with that and my age and being female, and having UC...combo connection.
My blood tests leans towards that. The specific markers wouldn't be active with PSC.

If I had obvious blockages, pain, turning yellow, I would have had one...for those reasons alone.

The vanco treatment is a new one, and definitely worth a shot after an MRCP. I'd still suggest putting off the ERCP unless one has blockages and needs to be stented. Oh, and besides, another ERCP is needed to remove the stent...that's also another risk.

q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!
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