Remicade infusions?

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Mud10
Regular Member


Date Joined Jan 2013
Total Posts : 33
   Posted 4/29/2013 7:49 AM (GMT -6)   
So after an 8 week to 9 week trial of 6MP my GI would like to start Remicade infusions. Again, I am frightened of doing this and am looking into a more hollistic approach. Not sure if that is the best idea or not.

I have had UC for a little over three years now and still havent felt "remission". I dont bleed, but have BMs way too often. Usually 10 to 15 sometimes 20 a day. Currently I am on Apriso and the 6MP. I have been on Apriso/Asacol for three years and have tried Prednisone as well as mesalamine enemas.

What is the process of "Remicade infusions"? and has anyone here been through that process? Should I be frightened and looking into a more hollistic approach to the whole thing? These drugs terrify me, especially when the success rate for me hasn't been very high.

ByeByeUC
Veteran Member


Date Joined Feb 2011
Total Posts : 3116
   Posted 4/29/2013 9:25 AM (GMT -6)   
I was on Remicade for a little while and it didn't help me. It has helped a lot of people though and the results vary from person to person. The process is pretty simple. You get 3 loading doses that are spaced closer together. Then after the loading doses you go every 8 weeks for the infusion. It takes about 2 hours for the infusions. I wasn't too thrilled about trying it but it was my last resort before heading into surgery so I felt I had to give it a try. Now I'm happy the Remicade didn't work because having surgery turned out to be a blessing in disguise.

If you haven't done the holistic approach yet, it probably wouldn't hurt to try. I tried that route as well and I actually wound up sicker. So because of that I don't have much faith in the holistic approach.

Everyone is different and its trial and error for what works for everyone. Best of luck to you.
Marianne

DX UC in 2005. Family history of UC.
Tried every drug-even Remicade-Tried diets-nothing worked-wanted my life back!
Step 1: J-pouch surgery (Laparoscopic restorative proctocolectomy w/ temporary diverting loop ileostomy) 6-25-10
Step 2: Take down surgery (Ileostomy reversal) 10/8/10
No more UC and no more drugs!! Very happy j-poucher!! :)

Post Edited (ByeByeUC) : 4/29/2013 8:29:54 AM (GMT-6)


ScienceGirl
Veteran Member


Date Joined Oct 2012
Total Posts : 511
   Posted 4/29/2013 9:55 AM (GMT -6)   
I've been on Remicade since early March, and I'm finished with my loading doses. I am not in remission yet, but after being essentially bedridden, I'm down to 5 BMs or less a day, and I'm able to work.

Remicade is an antibody against TNF-alpha, a molecule in the body that's often responsible for inducing inflammation. The antibody against it acts like a sink, neutralizing the TNFa and preventing it from inducing inflammation.

Like 6MP, the side effects of Remicade are pretty serious, but they're also rare. That's in contrast to prednisone, which has very serious side effects that are obnoxiously common.

Your mileage may vary in terms of your infusion center, but basically, you'll go to the doctor's office or the hospital every 8 weeks. They'll place an IV and hook you up to the Remicade, and you'll be there about 2 hours. After that, you'll have your IV removed, and you're all set.

There are three loading doses to get you started; the first two are 2 weeks apart, and the third one is 4 weeks later.

A lot of people on the forums here have tried Remicade unsuccessfully, but it's important to stress that: 1) the majority of people who post regularly on this forum are still in a flare, and 2) there's a huge number of UC sufferers who aren't on this forum.
26yo female
Diagnosed with moderate pancolitic UC 10/07, severe 2/13
Flares: 8/07-12/07, 7/10-1/11, 2/12-ongoing
Currently taking: Asacol HD 6x/day, 6MP 50mg/day, mesalamine enemas nightly
Remicade: 3/6/13, 3/18/13

Boston, you're my home

PSUDOC
Regular Member


Date Joined Jun 2007
Total Posts : 357
   Posted 4/29/2013 1:05 PM (GMT -6)   
Why is your GI looking to do Remi after only 8-9 weeks on 6MP? It typically takes, at minimum,3 months, and more likely 6+, to get any results from 6MP ... I would resist changing treatments until one has run its course.
Alison
Age 41, married w 10 yo girl and 4 yo boy, working professional
Diagnosed w UC 2002
Tried sulfas, 5ASAs, Imuran, Remicade, Canasa, Rowasa, and way too much Prednisone
Hospitalized 4 times w flares in 2012
Total colectemy 4/2/13
J-pouch construction planned for June 2013

Madcat25
Veteran Member


Date Joined Oct 2012
Total Posts : 1111
   Posted 4/29/2013 1:39 PM (GMT -6)   
Its not a very scary process. Nurses are always there in case you have a reaction which is rare. And starting infusions are 3 hours (2 for the infusion and 1 you sit there in case you have a reaction). The nurses are usually nice and so are the people there. Don't be afraid to try it worked for me and it may work for you!
ASK THE CAT
UC Forum Moderator

Ulcerative Colitis diagnosed Oct 2007. Prednisone for flares until Oct 2012. Half-remission from Remicade.
Currently on: Prednisone 5 mg, Imuran 100 mg, Remicade 300 mg (5 infusions)
Supplements: Ultimate Flora x 1, L-glutamine 1000 mg x 1

ScienceGirl
Veteran Member


Date Joined Oct 2012
Total Posts : 511
   Posted 4/29/2013 2:41 PM (GMT -6)   
PSUDOC--my doctor started me on 6MP and was trying to get me on Remicade at the same time. Often, 6MP boosts the effectiveness of Remicade.
26yo female
Diagnosed with moderate pancolitic UC 10/07, severe 2/13
Flares: 8/07-12/07, 7/10-1/11, 2/12-ongoing
Currently taking: Asacol HD 6x/day, 6MP 50mg/day, mesalamine enemas nightly
Remicade: 3/6/13, 3/18/13

Boston, you're my home
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