I've been on Remicade since early March, and I'm finished with my loading doses. I am not in remission yet, but after being essentially bedridden, I'm down to 5 BMs or less a day, and I'm able to work.
Remicade is an antibody against TNF-alpha, a molecule in the body that's often responsible for inducing inflammation. The antibody against it acts like a sink, neutralizing the TNFa and preventing it from inducing inflammation.
Like 6MP, the side effects of Remicade are pretty serious, but they're also rare. That's in contrast to prednisone, which has very serious side effects that are obnoxiously common.
Your mileage may vary in terms of your infusion center, but basically, you'll go to the doctor's office or the hospital every 8 weeks. They'll place an IV and hook you up to the Remicade, and you'll be there about
2 hours. After that, you'll have your IV removed, and you're all set.
There are three loading doses to get you started; the first two are 2 weeks apart, and the third one is 4 weeks later.
A lot of people on the forums here have tried Remicade unsuccessfully, but it's important to stress that: 1) the majority of people who post regularly on this forum are still in a flare, and 2) there's a huge number of UC sufferers who aren't on this forum.
Diagnosed with moderate pancolitic UC 10/07, severe 2/13
Flares: 8/07-12/07, 7/10-1/11, 2/12-ongoing
Currently taking: Asacol HD 6x/day, 6MP 50mg/day, mesalamine enemas nightly
Remicade: 3/6/13, 3/18/13
Boston, you're my home