Budesonide (difference between Uceris & Entocort??)

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barelyholdingon
New Member


Date Joined Mar 2013
Total Posts : 13
   Posted 5/11/2013 11:43 PM (GMT -6)   
So my doctor recently wrote me a script (a few weeks ago) for Budesonide, but was really kind of unhelpful as to where to go and what to do to get it ... so I am kind of on my own having to investigate and find out about it.

Called the pharmacy and found out for the 8 week course of pills its $1000 or something ...

Now for my previous expensive medicatiosn, due to my unfortunate finanical situation, I qualified for completely 'free' supplies of the drugs (examples would be Lialda, Dificid for my c.diff last year, and most recently Humira to name a few).

I was wondering if anyone knows of any similar programs for either Uceris or Entocort, and what the difference between the two is? As I recall I think I read people saying they had some issues or dislike for Entocort, whereas everyone seemed to rave about Uceris. If it is the same active drug in each steroid, I don't understand why the Uceris is so much better than the entocort? Is it the additives that cause less negative effects in the Uceris?

I am just really kind of in the dark on this.. so any info would be helpful. I found some things on the Uceris website about 'discounts' for people with insurance... but that's really not going to do me any good, and I was not able to find a proper phone # to call the company that makes Uceris.

Honestly I really don't care which of them I get (and if there's other similar options for Budesonide I'd like to know also), I just want to know the differences between them and if one is better then the other and for what reason, but honestly I think any of them would be MUCH better than this Prednisone I've been on for 6+ months now, I know how bad it is.

My doctor and I have been working on me getting off the prednisone, I was at 20mg but I have been weaning off it 5mg every 2 weeks, just recently went down to 10mg and I think I am noticing some bad things starting to happen again... so if possible I'd really like to try getting on the Budesonide ASAP now.

Any help anyone could provide as far as the difference between these 2 (and possibly others)? and also if they have any patience assistance programs similar to the ones I described would be greatly appreciated, thank you!!

justwantmylifeback
Regular Member


Date Joined Feb 2013
Total Posts : 27
   Posted 5/12/2013 12:23 AM (GMT -6)   
To put it in short, Budesonide is not a new drug and from my understanding its a steroid with effects like pred. However Uceris is a new drug although its based on on Budesonide it has delayed-release which is meant to target your colon and not your blood like other steroids (including Budesonide) and therefore side effects are supposed to be a lot less then other steroids.

I'm not sure why you got such a high quote $1000 for Budesonide it should be more like $100 while Uceris is a nice $1200 without insurance.
M 22,
UC diagnosed April 2012 - no remission yet
currently on 6MP 50mg daily, Uceris 9mg, Canasa 3x daily, Cortifoam 2x daily, SCD
also taking Vitamin D, Calcium, VSL#3 DS 1 sachet daily
Tried Asacol with SCD (4 months),

barelyholdingon
New Member


Date Joined Mar 2013
Total Posts : 13
   Posted 5/12/2013 2:19 AM (GMT -6)   
justwantmylifeback said...
To put it in short, Budesonide is not a new drug and from my understanding its a steroid with effects like pred. However Uceris is a new drug although its based on on Budesonide it has delayed-release which is meant to target your colon and not your blood like other steroids (including Budesonide) and therefore side effects are supposed to be a lot less then other steroids.

I'm not sure why you got such a high quote $1000 for Budesonide it should be more like $100 while Uceris is a nice $1200 without insurance.


I should've been more clear, it was $1000 or so for the Uceris specifically.

According to this site: http://www.medicinenet.com/budesonide/article.htm

The Entocort does the same thing as the Uceris ... that is why I was confused. It says the Entocort also targets the colon and not the blood stream...

imagardener2
Veteran Member


Date Joined Jan 2010
Total Posts : 3714
   Posted 5/12/2013 6:52 AM (GMT -6)   
I had no problems with Entocort but can't remember the price (been several years). Even though it says it "targets" the colon I still felt like Superwoman while on it, energy out the wazoo. I had no bad side effects, however when I stopped taking it the bleeding came back.

I didn't know it was the same as Budesonide.
Current diet=modified Paleo (sm amts of swiss cheese and some fruit OK)
In remission April 2010 after 10 years of UC with no remission ever
gluten-free (bleeding stopped) and dairy-free (less gas) started remission path+food diary
current meds=(9)Balsalazide+(2)Citrucel,(1) VSL#3 nightly
Rx meds have never worked for me except for mesalamine enema

garylouisville
Veteran Member


Date Joined Aug 2012
Total Posts : 6336
   Posted 5/12/2013 7:50 AM (GMT -6)   
Uceris is supposed to target the large intestine while Entocort releases farther up. Entorcort is used more for Crohns. Uceris is better for UC.
Asacol 400mgs 2 pillsX3; VSL#3 112.5mgs 1 pillX2; Prescrip Assist Probiotic 1 pill X 2;Vitamin D3 5000 ius 1 pillX2;Bentyl;DAO;Folic acid

Discontinued: Robinul; Natural - peppermint oil, Inflaguard (Boswellia), Pepto Bismol, Omega 3 fish oil, Imodium, Beano, Lactaid;Zymactive, Renew Life Probiotic 80 billion, Florastor, DGL, Monolaurin, slippery elm;black cherry concentrate

barelyholdingon
New Member


Date Joined Mar 2013
Total Posts : 13
   Posted 5/15/2013 12:00 AM (GMT -6)   
So in other words, Entocort and Uceris are both Budesonide, however they each have a different delivery mechanism, is this correct?

I just don't know really which one I should try to get... though I am not too confident I'll be able to get the Uceris free of charge, unless anyone knows of a patience assistance program for it?

Tornado6
Veteran Member


Date Joined Mar 2013
Total Posts : 1149
   Posted 5/15/2013 5:02 AM (GMT -6)   
Yes, there is an assitance program on their website, IF your insurance covers it, you'll have a $25 copay.
Ulcerative colitis / 35 / female

budesonide - 9 mg
budesonide enema
Imuran – 100 mg
Remicade - 7.5 mg / kg
Ca, Fe, Zn, Vit B Complex, Vit C, Vit D, Colostrum, Fish Oil, Kelp, L-glutamine, PD Ultra

FODMAP Elimination Phase 4/7/13

Prior: Colestyramine, Xifaxan, Lialda, Apriso, Symax Duotab, Imuran, Remicade, Prednisone, hydrocortisone enema, Align, acidophilus, SCD yogurt

Sweets7
Regular Member


Date Joined Feb 2008
Total Posts : 54
   Posted 8/11/2013 12:34 PM (GMT -6)   
You probably know everything i'm about to say by now. Uceris is not like prednisone because very little of the medicine enters the bloodstream. The target release area is the colon, not the small intestine (where entorcort is released and does no help for people with UC). It has already started to help me, so i'm keeping my fingers crossed.

The price is up there. I am posting a blog with some payment assistance offers for this med. hope this helped you or someone.
35 yr. old single female
as of 2012 - UC again.. Now I call it IBD because who knows what it is!
Crohn's Colitis dx in October 09
UC from 97-09
12mg Prednisone
150mg EFFEXOR ER
Imodium - 2 tabs 4 X /day (PRN)
Homeopathic Medicine - Pedophyllum peltatum, Cinchona
Calcium, vit D, vit K, multi vit, iron by infusion, B-12
Restricted Diet - No gluten, no dairy. **now only ORGANIC meat & produce**

Tornado6
Veteran Member


Date Joined Mar 2013
Total Posts : 1149
   Posted 8/11/2013 1:31 PM (GMT -6)   
Entocort does help with UC, and when combined with Entocort enemas, covers the exact same areas as Uceris, for a fraction of the cost.

Budesonide does have some systemic absorption in either form, but it is not as pronounced as Prednisone.
Ulcerative colitis / 36 / female

Imuran – 175 mg
Remicade - 7.5 mg / kg
Hydrocortisone / Mullein enema
Limited FODMAPs
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