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beatUC
Veteran Member


Date Joined Mar 2010
Total Posts : 1140
   Posted 6/2/2013 8:21 AM (GMT -7)   
So, my doc has taken me off Asacol after more than 10 years, doing my own research I found that there is a toxic plastic that was found in Asacol, leading to it being pulled from the market.
My questions are:

Should I get tested for this toxic plastic and if so, how do I go about it?

Is there a class action suit at this time?

How do the other drugs stack up to asacol?

I'm a bit apprehensive about switching maintenance meds, it's a delicate balance.
I'd like to know more about where I go from here.

Madcat25
Veteran Member


Date Joined Oct 2012
Total Posts : 1111
   Posted 6/2/2013 9:18 AM (GMT -7)   
Ahhh America. Sue first ask questions later). I suggest you talk to your doc and do a search of the forums (there was a big thread on this). Otherwise dont know much about it myself. Good luck!
ASK THE CAT
UC Forum Moderator

Ulcerative Colitis diagnosed Oct 2007. Prednisone for flares until Oct 2012. Half-remission from Remicade.
Currently on: Imuran 100 mg/1 day, Remicade 600 mg/6 weeks.
Supplements: L-glutamine 1000 mg/1 day, Fiber Smart 2 capsules/1 day.

beatUC
Veteran Member


Date Joined Mar 2010
Total Posts : 1140
   Posted 6/2/2013 9:21 AM (GMT -7)   
It's not about a lawsuit, I just wanted to know if the plastic found is Asacol is dangerous or harmless.
Also, I'm not American and don't live in the United States!
Madcat25, Thats a pretty nasty, nationalistic thing to say -especially for a moderator!

Post Edited (beatUC) : 6/2/2013 2:11:03 PM (GMT-6)


notsosicklygirl
Forum Moderator


Date Joined Dec 2008
Total Posts : 10595
   Posted 6/2/2013 9:30 AM (GMT -7)   
I have heard about asacol being pulled but I haven't heard any details about the coating or if we should get some kind of testing... I am curious about the same thing. I was on Asacol for about 5 years.
Co-moderator: Ulcerative Colitis
Diagnosed with Pancolitis, Laryngopharyngeal Reflux & Migraines. Battling Extreme Exhaustion.
Currently: 6mp (25mg) + Lialda (2400mg) + Canasa (1g PM)

garylouisville
Veteran Member


Date Joined Aug 2012
Total Posts : 7147
   Posted 6/2/2013 9:53 AM (GMT -7)   
I personally believe the toxic plastic thing is a load of crap. I don't think it exists, contrary to some published reports. Asacol HD has not been pulled and it is presumably made the same way as Asacol, just twice as big. Also, the new drug delzicol is nothing but a regular Asacol pill put inside of a capsule that dissolves in the stomach and nobody is talking about the plastic in that. The public has been duped into accepting that generic Asacol will not be available and that we must continue with the expensive meds. This all just magically happened right at the very same time the patent expires and generic Asacol would have become available. I'm not sure how this effects the generic Asacol that has been available in certain countries such as Canada.
Asacol 400mgs 2 pillsX3; VSL#3 112.5mgs 1 pillX2; Prescrip Assist Probiotic 1 pill X 2;Vitamin D3 5000 ius 1 pillX2;Bentyl;DAO;Folic acid

Discontinued: Robinul; Natural - peppermint oil, Inflaguard (Boswellia), Pepto Bismol, Omega 3 fish oil, Imodium, Beano, Lactaid;Zymactive, Renew Life Probiotic 80 billion, Florastor, DGL, Monolaurin, slippery elm;black cherry concentrate

beatUC
Veteran Member


Date Joined Mar 2010
Total Posts : 1140
   Posted 6/2/2013 10:00 AM (GMT -7)   
Gary -this doesn't look like a load of crap:

"In one case, the man taking Asacol for his ulcerative colitis, an inflammatory bowel disease, had a concentration of a dibutyl phthalate (DBP) metabolite in his urine measuring nearly 17,000 parts per billion, according to a case study reported by the Harvard/CDC team. The average for the general population was 46."

17,000 vs 46, that's a whole lot!
Imuran
Asacol
Rowasa
prednisone as needed

fightUC
Regular Member


Date Joined Jun 2011
Total Posts : 258
   Posted 6/2/2013 10:21 AM (GMT -7)   
I made a thread earlier titled "Asacol dibutyl phthalate" on THIS very forum, and somehow it was deleted. (I know I didn't delete it)

I made that thread when my Gastro (the same one who tried to push pred before anything else) Rx'd me Asacol HD.

Dibutyl Phthalate is pregnancy category C as it may cause testicular damage in developing fetuses.

Post Edited (fightUC) : 6/6/2013 12:25:38 AM (GMT-6)


garylouisville
Veteran Member


Date Joined Aug 2012
Total Posts : 7147
   Posted 6/2/2013 12:07 PM (GMT -7)   
beatuc: I'm not sure what that particular case study actually means. They themselves only mentioned ONE case. If it was so prevalent then why didn't they report many cases of high levels instead of just one? Maybe it is possible that in that one case the patient was actually ingesting something else which caused such a high level of DBP. Also, I'm not really understanding why regular Asacol is bad news while Asacol HD is ok to take. It looks like the same exact thing to me, just twice the dose. On top of that I'm not understanding why Asacol is bad news but if you put the Asacol in a capsule that dissolves in the stomach then all of a sudden it is ok, no DBP to worry about. Somehow there is a lot more to this than meets the eye. I often roll my eyes at those who talk medical conspiracies but this might actually have some meat to it. It's just too convenient that this all happened exactly at the time the patent was running out.
Asacol 400mgs 2 pillsX3; VSL#3 112.5mgs 1 pillX2; Prescrip Assist Probiotic 1 pill X 2;Vitamin D3 5000 ius 1 pillX2;Bentyl;DAO;Folic acid

Discontinued: Robinul; Natural - peppermint oil, Inflaguard (Boswellia), Pepto Bismol, Omega 3 fish oil, Imodium, Beano, Lactaid;Zymactive, Renew Life Probiotic 80 billion, Florastor, DGL, Monolaurin, slippery elm;black cherry concentrate

notsosicklygirl
Forum Moderator


Date Joined Dec 2008
Total Posts : 10595
   Posted 6/2/2013 12:50 PM (GMT -7)   
i wouldn't be surprised if it's BS and just a way to continue making companies unable to make a generic form of the medication. Is the new drug generic? I know asacol was about to be generic.

I did not remove any threads. I don't see any reason for that to be removed unless there was some kind of violation of the terms and even in that case, it would have most likely been locked and reviewed.
Co-moderator: Ulcerative Colitis
Diagnosed with Pancolitis, Laryngopharyngeal Reflux & Migraines. Battling Extreme Exhaustion.
Currently: 6mp (25mg) + Lialda (2400mg) + Canasa (1g PM)

notsosicklygirl
Forum Moderator


Date Joined Dec 2008
Total Posts : 10595
   Posted 6/2/2013 12:52 PM (GMT -7)   
is this the topic you're looking for
www.healingwell.com/community/default.aspx?f=38&m=2689473
Co-moderator: Ulcerative Colitis
Diagnosed with Pancolitis, Laryngopharyngeal Reflux & Migraines. Battling Extreme Exhaustion.
Currently: 6mp (25mg) + Lialda (2400mg) + Canasa (1g PM)

fightUC
Regular Member


Date Joined Jun 2011
Total Posts : 258
   Posted 6/2/2013 6:28 PM (GMT -7)   
No notsosicklygirl, I made the topic a few months ago and I remember a very desperate mother replied to it. I did not reply back to her and I regret it.
Hoping for a cure, this is what I think helps me:
cigs for constipation, garlic, multiple brands of probiotics, Spirulina and Chrollela (nasty! but seems to help), high lignan flax oil, Apriso (occasionally), Canasa (dipped in liquid vitamin E sometimes), sfRowasa.

fruitgirl
Veteran Member


Date Joined Feb 2009
Total Posts : 6980
   Posted 6/3/2013 6:44 AM (GMT -7)   
fightUC, is this the thread you're looking for?
http://www.healingwell.com/community/default.aspx?f=38&m=2530577
Symptomatic remission as of May 2009
Colonoscopy in Oct. 2011 showed no inflammation
Symptoms began in Nov. 2008, about 4 weeks after birth of first child; diagnosed with pancolitis in Jan. 2009
Second child born March 2013; no post-partum flare up thus far.
Meds: Apriso (Four 0.375 g pills once daily), Mesalamine enema twice weekly, multivitamin, vitamin D, probiotic

fightUC
Regular Member


Date Joined Jun 2011
Total Posts : 258
   Posted 6/3/2013 8:11 AM (GMT -7)   
fruitgirl! wow yes that was the one! amazing! so I guess it wasn't mysteriously deleted haha, yay
Hoping for a cure, this is what I think helps me:
cigs for constipation, garlic, multiple brands of probiotics, Spirulina and Chrollela (nasty! but seems to help), high lignan flax oil, Apriso (occasionally), Canasa (dipped in liquid vitamin E sometimes), sfRowasa.

fruitgirl
Veteran Member


Date Joined Feb 2009
Total Posts : 6980
   Posted 6/3/2013 8:19 AM (GMT -7)   
Glad I could help! If you want to know how I found it let me know and I'll try to walk you through it. Basically, I used the function where you can sort the forum by "started by" instead of "last comment" to find all of the posts you started. It takes a bit of time, but once you know what you're doing it's pretty easy.
Symptomatic remission as of May 2009
Colonoscopy in Oct. 2011 showed no inflammation
Symptoms began in Nov. 2008, about 4 weeks after birth of first child; diagnosed with pancolitis in Jan. 2009
Second child born March 2013; no post-partum flare up thus far.
Meds: Apriso (Four 0.375 g pills once daily), Mesalamine enema twice weekly, multivitamin, vitamin D, probiotic

Sara14
Veteran Member


Date Joined Mar 2007
Total Posts : 3770
   Posted 6/3/2013 8:36 AM (GMT -7)   
Check out this thread for previous discussion about this: http://www.healingwell.com/community/default.aspx?f=38&m=2689473&p=7

beatUC - I just started Delzicol a week ago and it's working the exact same as Asacol so far. I was on Asacol since 2007. Delzicol is exactly the same except they took out the DBP and replaced it with another inactive ingredient.
29 years old; diagnosed pancolitis March 2007

Just started Delzicol, 6 capsules, 2xday; Rowasa nightly; Ortho Tri-Cyclen; Singulair; Allegra; Deva multivitamin; B-12. Vegan diet.

"I know you're tired, but come, this is the way." - Rumi

Chrissysoul
Veteran Member


Date Joined Jun 2012
Total Posts : 1055
   Posted 6/3/2013 10:07 AM (GMT -7)   
I'm gonna ask my gi about this I'm in her office right now. I am also on Asacol hd and this alarms me. I'm pregnant too so I hope this isn't true! I will post what I find out

ByeByeUC
Veteran Member


Date Joined Feb 2011
Total Posts : 3317
   Posted 6/3/2013 11:00 AM (GMT -7)   
Is there an article or something to back this up? I swallowed a boat load of asocol when I had UC. I searched and didn't find anything that said it contained a toxic plastic hence why it was pulled.
Marianne

DX Pancolitis in 2005. Family history of UC.
Tried every drug-even Remicade-Tried diets-nothing worked-wanted my life back!
Step 1: J-pouch surgery (Laparoscopic restorative proctocolectomy w/ temporary diverting loop ileostomy) 6-25-10
Step 2: Take down surgery (Ileostomy reversal) 10/8/10
No more UC and no more drugs!! Very happy j-poucher!! :)

twiggs
Veteran Member


Date Joined Mar 2012
Total Posts : 784
   Posted 6/3/2013 11:11 AM (GMT -7)   
I am taking max dose of 6 per day of the 800 HD now to get over this flare. I was reading and didn't know that it is not recommended to take for longer than 6 weeks per the detailed instructions on their website. Can any of you tell me how much and how long you have taken it? I will be seeing my doc in 2 weeks to talk to him and will talk about other maintenance meds and options at that time. It sounds like I may be on this for a while. How do you all feel about the companies recomendation of 6 weeks max on the 800hd?
 
 
I guess my only other options would be delzicol or colazal since asacol 400 wont be avail in the states?
 
Thanks

Post Edited (twiggs) : 6/3/2013 11:14:00 AM (GMT-6)


Meredith610
Regular Member


Date Joined Oct 2011
Total Posts : 48
   Posted 6/3/2013 11:30 AM (GMT -7)   
From my understanding, they say the 6-weeks thing because, as most pharmaceutical companies do, they rushed the trials to get the product to market. So in essence, they say 6-weeks only because they didn't study over a longer period of time because time = money. "Rushing trials" sounds dangerous, but really, Asacol HD is just regular Asacol in bigger pill form so the longer trial studies weren't really needed for the HD as regular Asacol was already well-established as safe for long-term use. Gotta love politics and corporate greed...

beatUC
Veteran Member


Date Joined Mar 2010
Total Posts : 1140
   Posted 6/3/2013 4:14 PM (GMT -7)   
Byebyeuc:
Every study I post here usually gets slammed, but here ya go:

www.environmentalhealthnews.org/ehs/news/prescription-drugs-can-deliver-high-doses-of-phthalates

MilkyChocoxD
Regular Member


Date Joined Feb 2013
Total Posts : 117
   Posted 6/3/2013 9:26 PM (GMT -7)   
I don't believe this is real, if Asacol has been on the market for more than 10 years, I'm sure someone would've noticed before and it would've been pulled a while ago. And if there is any kind of plastic I don't believe it's toxic or else people would've gotten sick and they would've eventually linked it back to Asacol.

quincy
Elite Member


Date Joined May 2003
Total Posts : 25881
   Posted 6/3/2013 9:29 PM (GMT -7)   
Asacol's been on the market since 1987 or 1988.

Nothing's been pulled in Canada...and there's generic version of it here as well. Why not in the US? anyone got any info on that?

q
*Heather* I give suggestions, do with them what you will.
Status: ...Asacol 3 @ 2x daily; Salofalk enema @ 3rd night (nightly/ flares, tapered/maintenance)
~diagnosed January 1989 UC (proctosigmoiditis)
~Bentylol 20mg as needed; Zantac 150mg; Pulmicort/Airomir (asthma);Effexor XR 37.5 (depression)
~vitamins/minerals/supplements; Probiotics....(RenewLife Ultimate Flora Critical Care+Primadophilus Reuteri capsules @ bedtime)
~Metamucil capsules 6 twice daily with meals; Vitamin D 4500 IU
~URSO for PBC(or PSC?) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS" worth it !!!

tap
Regular Member


Date Joined May 2008
Total Posts : 472
   Posted 6/4/2013 4:51 AM (GMT -7)   
Here is the FDA's safety comment with respect to pregnancy.

www.fda.gov/Safety/MedWatch/SafetyInformation/ucm215476.htm

beatUC
Veteran Member


Date Joined Mar 2010
Total Posts : 1140
   Posted 6/4/2013 5:22 AM (GMT -7)   
This Asacol thing is is the preliminary stages. The typical process is, someone has toxicity from the drug, it's identified by medical tests, then another, and another and so on.
The fact that there is information out there linking toxic plastic and toxicity in patients taking Asacol, then the drug is pulled from the market speaks volumes.
This situation will play out legally, which may take years before we know what the real deal is.
Yes, this whole thing may be linked to the patent running out, but if documented birth defects are found, the shark lawyers will tear into this company and reap millions while we Asacol users will end up with $20 (or less) each and a lifetime of tests for toxicity....
Gotta love our legal system.
Imuran
Asacol
Rowasa
prednisone as needed

fightUC
Regular Member


Date Joined Jun 2011
Total Posts : 258
   Posted 6/4/2013 9:24 AM (GMT -7)   
Why can't we have an oral mesalamine that is JUST MESALAMINE? Can't we use Apriso's delivery method without the aspartame and edible ink/crap? Like canasa or sfRowasa, please!
Hoping for a cure, this is what I think helps me:
cigs for constipation, garlic, multiple brands of probiotics, Spirulina and Chrollela (nasty! but seems to help), high lignan flax oil, Apriso (occasionally), Canasa (dipped in liquid vitamin E sometimes), sfRowasa.
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