Repeat Remicade Level Test?

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zarch
Regular Member


Date Joined Apr 2015
Total Posts : 40
   Posted 6/16/2017 8:30 PM (GMT -6)   
about 3 weeks ago I had a blood test done to check my Remicade levels to see if the medication has failed me completely, or if I just need an increased dosage. I had the test done about 10 days after my last infusion.

I finally got in touch with my GI doctor today, and she wants to repeat the test about a week or two before my next infusion. I was hoping not to have to wait longer as I want to get of pred. as soon as possible.

I'm not exactly sure what test I had done, but I thought it would check my blood for antibodies against Remicade. Is it normal to get a repeat test? Thanks!

iPoop
Forum Moderator


Date Joined Aug 2012
Total Posts : 10527
   Posted 6/17/2017 5:09 PM (GMT -6)   
The infliximab serum trough (minimum) and antibody test measures two things.

Do you have antibodies to remicade and that component can be run at any time. Small amounts of antibodies can be fought with a higher dose of remicade. High levels of antibodies mean switching to humira or simponi.

What is your minimum remicade concentration within 24 hours of your next infusion? That can only be run 24 hours before your next infusion and helps with dosing, is your concentration fine? If no then the frequency can be decreased to every 6 weeks, 4 weeks, and/or you can get 10mgs per kilogram instead of 5mgs. If yes, means you've failed the tnf-alpha clas of biologics.
Moderator Ulcerative Colitis
John
, 39, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; 75mgs 6MP, 4.8g Lialda, and rowasa

I swore to myself that once i was off of prednisone that I'd burn both the pills and bottle with great hedonistic enjoyment: booze, food, and dance. And if I ever need a colectomy... ;-)

zarch
Regular Member


Date Joined Apr 2015
Total Posts : 40
   Posted 6/17/2017 10:01 PM (GMT -6)   
Thanks for replying iPoop. I thought I had the antibody test done (or does the test check both antibodies and levels?). My doctor did not give me any info about my test results, just to get it repeated about a week or so before my next infusion. She didn't mention anything about 24 hours before. Should I call her about this?

iPoop
Forum Moderator


Date Joined Aug 2012
Total Posts : 10527
   Posted 6/18/2017 6:04 AM (GMT -6)   
Same test and two results. I'd call and ask what ypur doctor's intending to use tge test, when you shpuld have it done, and what your last test results were.
Moderator Ulcerative Colitis
John
, 39, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; 75mgs 6MP, 4.8g Lialda, and rowasa

I swore to myself that once i was off of prednisone that I'd burn both the pills and bottle with great hedonistic enjoyment: booze, food, and dance. And if I ever need a colectomy... ;-)
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