If you're already at the maximum dose of oral mesalamine (at least 4,000mgs a day) and have a rectal-route mesalamine enema (4gs a day) then I'd cobsider a low dose of azathioprine.
Moderator Ulcerative Colitis
John, 39, UC Proctosigmoiditis
Rx: Remicade @5mgs/kg/6wks; 75mgs 6MP, 4.8g Lialda, and rowasa
I swore to myself that once i was off of prednisone that I'd burn both the pills and bottle with great hedonistic enjoyment: booze, food, and dance. And if I ever need a colectomy... ;-)