non- refrigerated probiotics

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asobel
Regular Member


Date Joined Oct 2004
Total Posts : 27
   Posted 11/13/2007 10:26 AM (GMT -6)   
Hello-
I have been taking natren probiotics, that need refrigeration, for a month or so now and now I'm planning on traveling for about a year. I was telling my GI this and he said that I could take probiotics that don't be refrigerated, he gave me a sample of this product called Align. I am just wondering why they wouldn't need to be refrigerated while others do? It makes me a bit skeptical. any thoughts?

pb4
Elite Member


Date Joined Feb 2004
Total Posts : 18002
   Posted 11/13/2007 1:38 PM (GMT -6)   
I think if it were me, as I take a refridgerated probiotic myself, I would ask a health food store if they had a non-refridgerated one that was comparable to the fridgerated one you're currently taking...since it is only for travelling I don't see it being a problem, afterall any probiotic is better than no probiotic.

:)


My bum is broken....there's a big crack down the middle of it!  LOL  :)


UMDTerp2001
Regular Member


Date Joined Sep 2006
Total Posts : 246
   Posted 11/13/2007 1:55 PM (GMT -6)   
I have good luck with Garden of Life Primal Defense Probiotics which do not require refrigeration.
 
 
__________________________________________________________________________________
- 29 y/o single IT professional male residing in Northern VA, USA
- UC Diagnosis - April, 2006 - Symptoms were sudden and drastic
- GI did not determine type of UC as I was too inflamed during the c-scope
- Completed 3rd Prednisone taper on 4/13/07 - Tapered from early January through mid-April after being hospitalized from a bad flare with anemia & severe joint pain.
- Currently in remission and enjoying life again since getting out of the hospital in early Jan 07' from a nasty flare
- Survive on 4 Colazal/day, 1 GNC Multivitamin, occassional Fish oil & Primal Defense Probiotics
- Enjoy the outdoors, relaxing and spending time with family and friends


relativelyquantum
Regular Member


Date Joined Sep 2007
Total Posts : 196
   Posted 11/13/2007 2:00 PM (GMT -6)   
Probiotics are mostly freeze-dried, where the water is removed and the bacteria remain suspended. This prolongs their life. This is why it is often best to keep them cool. However, they last longer when in cold conditions generally speaking, but usually they are fine at room temperature, especially if it is only a few weeks, since exposure to high temperature or air decreases their viability. Most will die off when over a 100 degrees F (hence, a fever kills many microbes). A year is a long time, so you should check the expiration date, because even with a metabolism greatly slowed down, they can still die off with time, so you won't be getting quite the microbial count you think you are. I am skeptical certain brands are better at preserving (maybe more air-tight), but it depends more on the particular probiotic strains and how sensitive they are to heat. Even with that said, it is hard to say because there really are not the standards out there to ensure most of these claims, but there is a lab that does some testing: http://www.consumerlab.com/results/probiotics.asp

Depending on where you are traveling, you might find food sources that will give you the same benefits, especially in europe (cheeses, fermented milks, sauerkraut, etc.), though asia has kimchi and miso.
Pancolitis '04
Yet to go into remission, Flare-up since Aug 12th and still atempting to work in the midst of it
On Lialda (2/dy), probiotics, Oriental Medical Tea & Prescribed Diet, Greens+, Fish Oil


Red_34
Forum Moderator


Date Joined Apr 2004
Total Posts : 22057
   Posted 11/13/2007 2:25 PM (GMT -6)   
Pro-Bio has a shelf life of 12 months not refridgerated and 24 months refridgerated. I'm not sure though what the difference is between Pro-Bio and other ones.
 @--->--SHERRY--<---@
Left sided Uc -'92 - Colazal, 6mp, Prilosec, Biotin, Forvia, Pro-Bio 
Allergies - Singulair, Astelin(got the script - just haven't tried it yet!)
Secondary Reynauds Syndrome - '04 - Norvasc
Fibromyalgia - '06 
PLEASE HELP HEALINGWELL CONTINUE TO HELP OTHERS BY CLICKING HERE: DONATE
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relativelyquantum
Regular Member


Date Joined Sep 2007
Total Posts : 196
   Posted 11/13/2007 2:30 PM (GMT -6)   
Another gold star for Pro-Bio...
Pancolitis '04
Yet to go into remission, Flare-up since Aug 12th and still atempting to work in the midst of it
On Lialda (2/dy), probiotics, Oriental Medical Tea & Prescribed Diet, Greens+, Fish Oil


quincy
Elite Member


Date Joined May 2003
Total Posts : 25764
   Posted 11/13/2007 2:41 PM (GMT -6)   
plus it has good strains in it...I'd give it another gold star.

q
*Heather*Status:mini flare June 23* 6asacol daily+ Salofalk (tapered every 4th night)
~diagnosed January 1989 UC (proctosigmoiditis)
~5ASA: Asacol + Salofalk enemas (increase for flares tapered to maintenance)
~Bentylol (dicyclomine) 20mg as needed
~vitamins/minerals 
~Probiotic 2 (Natural Factors Protec) + 1 (Primadophilus Reuteri) at bedtime
~Natural Factors Multi Digestive Enzymes with supper
~Ranitidine,Pariet (reflux) Effexor XR 75mg;  Pulmicort/Airomir (asthma)
~URSO for PSC (or PBC) 500mg X 2 daily (LFTs back to NORMAL!!)
My doc's logic.. "TREAT (FROM)BOTH ENDS"  worth it !!!


relativelyquantum
Regular Member


Date Joined Sep 2007
Total Posts : 196
   Posted 11/13/2007 5:01 PM (GMT -6)   
I much agree.  I also want to try Culturelle, which has Lactobacillus rhomnosus GG, which has shown very effective with a number of diseases and conditions, including IBD.  Looks like a good quality product too.
http://www.culturelle.com/

Pancolitis '04
Yet to ever go into remission, additional Flare-up since Aug 12th and still atempting to work in the midst of it Time off work since 10/17. 
 
Finally seeing some improvement; likely was complicated with a digestional yeast overgrowth.
 
On Lialda (2/dy), probiotics, Oriental Medical Tea & Prescribed Diet, Fish Oil


Bmshurt
Regular Member


Date Joined Oct 2007
Total Posts : 28
   Posted 11/13/2007 5:54 PM (GMT -6)   
Many of the Probiotic brands have Lactobacillus rhomnosus GG.  I do however like the idea that Culturelle is available in local stores versus ordering off the internet and paying shipping. Think i will check for Culturelle next time im out. I currently take Natures Bounty Extra Strength Probiotic. It too can be purchased in store but i found that its missing a few of the other ingredients but has the main ones, including calcium.
Here is a list of the should be Probiotic ingredients and brief explanation:
 

Lactobacillus acidophilus performs many critical functions including inhibiting pathogenic organisms and preventing them from multiplying and colonizing, when present in sufficient numbers.

 

Bifidobacterium bifidum is a prominent probiotic microorganism that takes up residence primarily in the mucous membrane lining of the colon. B. bifidum prevents the colonization of invading pathogenic bacteria by attaching to the intestinal wall, crowding out and taking nutrients from these unfriendly bacteria and yeasts.

 

Lactobacillus rhamnosus is one of the most intensely studied probiotic strains. Its advantages in the treatment of gastrointestinal disorders are well documented. In laboratory animal studies, L. rhamnosus has been shown to inhibit the growth of colon tumors, especially when supplementation with L. rhamnosus is started before tumors were induced with a carcinogenic substance.

 

Lactobacillus salivarius has the unique ability to eradicate the dreaded Helicobacter pylori (H. pylori) bacteria which is now known to be the major cause of peptic ulcers. The H. pylori microorganism interferes with the normal defenses against stomach acid and/or produces a toxin that contributes to peptic ulcer formation.

 

Bifidobacterium longum is an abundant organism found in the large intestine. B. longum has been found to reduce the frequency of gastrointestinal disorders (diarrhea, nausea, etc.) during antibiotic use. Furthermore, in the Cancer Research Journal, researchers report that dietary intake of B. longum significantly inhibits the development and growth of colon, liver and breast cancers in laboratory animal models.

 

Lactobacillus casei is reported to have the most potent protective activity against the potentially lethal Listeria bacteria than any other beneficial bacteria. Reports in the medical journal Cancer Letters show that L. casei not only shows an inhibiting activity in tumor cells but it also has a beneficial stimulating activity in normal cells.

 

Lactobacillus lactis acts as a natural antibiotic, which reduces the ability of pathogenic bacteria to grow and cause infection. It is especially effective against the bacteria Listeria monorytogenes, which causes severe food poisoning.


Medication:
Prednisone 20MG Daily
Imuran x2 Daily
Probiotic x2 Daily
Multivitamin x1 Daily
Oscal Calcuim Tabs X2 Daily
Fish Oil x1 Daily
 
Diagnosed with UC in May of 2007
 


munchkindd
Regular Member


Date Joined Oct 2007
Total Posts : 348
   Posted 11/13/2007 6:17 PM (GMT -6)   
Very Interesting...........I was just about to log in and ask some questions about pro biotics.  What stores can these be purchased in?  Is there a big variety to choose from (hope not)  How will I know if I'm getting the right one?  Are the prices better online?  I am about to give these a try as soon as I can...........

diagnosed with uc 27 years ago.
asacol 400 mg 3 tabs 3x a day
hoping for remission soon


munchkindd
Regular Member


Date Joined Oct 2007
Total Posts : 348
   Posted 11/13/2007 6:54 PM (GMT -6)   
is there a brand of pro biotics that has all the listed ingredients that Bmshurt listed above?
diagnosed with uc 27 years ago.
asacol 400 mg 3 tabs 3x a day
hoping for remission soon


pb4
Elite Member


Date Joined Feb 2004
Total Posts : 18002
   Posted 11/13/2007 7:36 PM (GMT -6)   
Reuteri is also very necessary...
 
Reuteri stimulates gastrointestinal epithelial cell development and improves intestinal cell structure leading to more efficient nutrient uptake, enhanced physical growth and overall better health.


Reuteri is the only lactobacillus species to produce and secrete reuterin, which has been shown to exhibit broad spectrum antimicrobial activity.

Reuteri uniquely contains the specific protein "AGGH" that encourages lactobacteria to cluster and colonize in the intestinal tract.

In clinical use, Reuteri effectively colonized in over 90% of patients. Reuteri supplementation is clinically shown to promote healthy digestion and intestinal integrity in humans. It is also being researched for cholesterol control, nutrient absorption, immune system support, seasonal respiratory health, and vaginal health.
 
 
There is this link as well...
 
 
 
 
:)


My bum is broken....there's a big crack down the middle of it!  LOL  :)


munchkindd
Regular Member


Date Joined Oct 2007
Total Posts : 348
   Posted 11/13/2007 8:18 PM (GMT -6)   
is there a particular brand that has all this? I'm very confused on what to look for and where to look for it
diagnosed with uc 27 years ago.
asacol 400 mg 3 tabs 3x a day
hoping for remission soon


icanrace
Regular Member


Date Joined Sep 2007
Total Posts : 204
   Posted 11/14/2007 9:00 PM (GMT -6)   
bump
Presciptions:
2400mg of Asacol daily = (6) 400mg pills)
30mg of Prednisone daily = (3) 10mg pills)
 
Supplements:
Pro-Bio
fish oil
multi-vitamin
additional calcium & vitamin D
Bi-Flex (joint support)
creatine
protein bars / powders
BCAA's
No-Xplode

started Prednisone & Asacol on Thursday 10-4-2007

10-22-07- coming out of about an 8 week flare (my first one ever)


Susiebuddy
Veteran Member


Date Joined Feb 2005
Total Posts : 1373
   Posted 11/14/2007 9:55 PM (GMT -6)   
I take Culturelle and have had much success with it.. I couldn't eat cheese or drink milk and now I can since taking it. It does not require refridgeration and it's very inexpensive, about 15 bucks for a 30 day supply. You can get it at most drug stores or pharmacies, the one here in Seeley Lake MT doesn't carry it, but they ordered it for me and I'll pick it up tomorrow.
SusieBuddy  
Diagnosed with U/C January 31st, 2004, IBS on July 21st, 2006, Dr says possible Crohn's...We'll see....
 
Meds: Rowasa enema's - Back to every night... probably forever!!!
         Canasa 1000mg. AM Only when needed, - Bentyl 10mg. As needed, -         Nexium - 40mg, 1x per day, - Xanax .5mg as needed,  Effexor 37.5mg. 
         Culturelle 1x a day 
         http://www.myspace.com/77016897         


princesa
Veteran Member


Date Joined Aug 2007
Total Posts : 2198
   Posted 11/16/2007 1:27 PM (GMT -6)   
Here's another link to a probiotic formula Mercola touts that doesn't require refrigeration:

http://www.mercola.com/products/complete-probiotics
 
 
munchkindd said...
is there a brand of pro biotics that has all the listed ingredients that Bmshurt listed above?

Custom Probiotics six strain blend has the first four strains listed.

http://customprobiotics.com/Merchant2/merchant.mvc?Screen=PROD&Product_Code=1013&Category_Code=

 

munchkindd said...
What stores can these be purchased in?  Is there a big variety to choose from (hope not)  How will I know if I'm getting the right one?  Are the prices better online?  I am about to give these a try as soon as I can...........

Health food stores are your best bet, if you want to purchase locally. If you have an alternative physician or naturopath locally, you might be able to purchase quality probiotics there. Even the big mainstream stores like Wal-Mart carry some these days, but they may not be the best quality. I purchase mine online. I'm currently using Custom Probiotics and Natren.

Unfortunately, there is a wide variety of brands out there and there isn't a perfect brand that works for everyone. There are some tried-and-true brands members here will recommend, but ultimately, you'll just have to try a few and see what works for you.


Diagnosed with ulcerative colitis spring 1999
 
Therapeutic dose sulfasalazine, back on a pred taper for first flare in years. Down to 10 mg and feeling much better.
Probiotics, l-glutamine and fish oil caps. George's aloe vera juice and Mucosaheal.
 
 

Post Edited (princesa) : 11/16/2007 11:39:14 AM (GMT-7)


Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2775
   Posted 11/16/2007 6:23 PM (GMT -6)   
Interesting links, Princesa. Mercola is always interesting- sometimes he can get overboard on stuff, especially when he is nvolved in selling the stuff to his patients, but nonetheless at least he thinks outside the box. Customprobiotics is certainly high quality. Primal Defense is one of my mainstays in part because it doesn't officially require refridgeration (although most any probiotics, with a few specific strain exceptions, benefit at least long term from refridgeration, and tend to die off quite quickly in high heat eg 90F +). I think it's because it;s core probiotic strains are the soil-based bacterias that do not need any refridgeration, but it does contain acidophilus and bifidobacteria too and those certainly would die off if unrefridgerated.
Pancolitis dx'd 1986, full med-free remission 88-97
Flaring or simmering ever since
10 20 17.5 15 12.5 mg pred, 100 mg Imuran
Probiotics (Primal Defense and others), TSO
Turmeric/circumin, fish oil, many vits/minerals
Lower-carb version of Specific Carb Diet (SCD)
 
 
 


relativelyquantum
Regular Member


Date Joined Sep 2007
Total Posts : 196
   Posted 11/16/2007 6:39 PM (GMT -6)   
I am not sure there is an abundance of Lactobacillus rhomnosus GG, because most brands do not contain the strain in concentration (i.e. GG in this case) and I believe it is patented, but I'm sure if one looks online you can find just about anything or combination... otherwise this particular stain does not seem common when I check the labels at food stores or it is not clear which ones they are using.

As far as what to buy, princesa has a good recommendation. Sadly there are not regulations on the number counts (except for yogurt) and quality of the microbes, as well as their preservation, so it may be best to buy from larger companies that are held to stricter standards and are known for their quality. What I've done is just browse through the many different brands and get as much variety in microbial strains (or at least species) that I can. So if you want all the ones Bmshurt mentioned, then just read through the labels... though customizing sounds like a great idea.

Susie, good to hear it has helped. I just started a couple days ago.
Pancolitis '04
Yet to ever go into remission, additional Flare-up since Aug 12th and still atempting to work in the midst of it Time off work since 10/17. 
 
Finally seeing some improvement; likely was complicated with a digestional yeast overgrowth.
 
On Lialda (2/dy), probiotics, Oriental Medical Tea & Prescribed Diet, Fish Oil


Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2775
   Posted 11/16/2007 7:05 PM (GMT -6)   
I agree that it's a real shame that there isn;t better documentation on what the off the shelf probiotic counts of these various brands are, as oppsoed to their official claims.

An alternative MD made a good suggestion once to me: that it's wise to rotate probiotics around and not keep taking the same ones day in, day out. I do tend to stick with those I know help, but once I do find a variety of brands that seem high quality and don't hurt me, I plan to mix them up a bit- take combinations and/or on and off spurts- sort of makes sense to me intuitively, to prevent jeep the competition (pathogenic bacteria) on their toes.

Mercola's biggest pearl of wisdom in the link Princesa posted was that no single probiotic seems to help everyone- it is a very individual thing and requires some serious trial and error and food / supplement/ symptom logging.
Pancolitis dx'd 1986, full med-free remission 88-97
Flaring or simmering ever since
10 20 17.5 15 12.5 mg pred, 100 mg Imuran
Probiotics (Primal Defense and others), TSO
Turmeric/circumin, fish oil, many vits/minerals
Lower-carb version of Specific Carb Diet (SCD)
 
 
 


icanrace
Regular Member


Date Joined Sep 2007
Total Posts : 204
   Posted 11/18/2007 4:00 PM (GMT -6)   
I've been taking Pro Bio and seem to be doing really well with it. After reading about Culturelle, I'm half tempted to try it. I need to buy one or the other but not sure what to do. Ugh!
Culturelle is about 7.00 cheaper but I wonder if it would be as effective.
Presciptions:
2400mg of Asacol daily = (6) 400mg pills)
30mg of Prednisone daily = (3) 10mg pills)
 
Supplements:
Pro-Bio
fish oil
multi-vitamin
additional calcium & vitamin D
Bi-Flex (joint support)
creatine
protein bars / powders
BCAA's
No-Xplode

started Prednisone & Asacol on Thursday 10-4-2007

10-22-07- coming out of about an 8 week flare (my first one ever)


munchkindd
Regular Member


Date Joined Oct 2007
Total Posts : 348
   Posted 11/18/2007 8:19 PM (GMT -6)   
thanks to everyone for all the input on pro-biotics. Still seems a bit confusing. I've never attempted taking any of these. Does anyone take just acidophillius????
diagnosed with uc 27 years ago.
asacol 400 mg 3 tabs 3x a day
hoping for remission soon


pb4
Elite Member


Date Joined Feb 2004
Total Posts : 18002
   Posted 11/18/2007 8:41 PM (GMT -6)   
I've taken just acidophilus in the past with hardly noticable improvements (something is always better than nothing) but found the most success with primadophilus reuteri.

:)
My bum is broken....there's a big crack down the middle of it!  LOL  :)


relativelyquantum
Regular Member


Date Joined Sep 2007
Total Posts : 196
   Posted 11/19/2007 3:40 AM (GMT -6)   
munchkindd,
Yes, it can get confusing. You might want to try just taking something that lists several microbes under the ingredients or somewhere on the label and that you can find at a local store. You may benefit for just your standard type. Or try one or some of the ones mentioned here. If you are not satisfied with the results, then make a list of the specific probiotic bacteria and yeasts that we mentioned on the post or other posts and start looking for them specifically.

This disease is not simple and not surprisingly all the medications and alternative therapies can also be complex. The best thing is to be educated in the options, even if it takes some time and we can all learn from one another.
Pancolitis '04
Yet to ever go into remission, additional Flare-up since Aug 12th and still atempting to work in the midst of it Time off work since 10/17. 
 
Finally seeing some improvement; likely was complicated with a digestional yeast overgrowth.
 
On Lialda (2/dy), probiotics, Oriental Medical Tea & Prescribed Diet, Fish Oil


munchkindd
Regular Member


Date Joined Oct 2007
Total Posts : 348
   Posted 11/19/2007 9:18 AM (GMT -6)   
that's what I wanted to do, try something that I can purchase locally that has several different microbes, but I am not having any luck finding them. I've tried CVS, Brookes, Walmart, BJ's Wholesale Club. I even tried GNC health and they had 1 product which had only 1 of the ingredients. I'd really like to be able to purchase them around here. (Massachusetts) I settled for the only one that CVS carried, which is the Acidophillius (sp), I figure one is better than nothing? I'll still keep looking though................
diagnosed with uc 27 years ago.
asacol 400 mg 3 tabs 3x a day
hoping for remission soon


Probiotic
Veteran Member


Date Joined Mar 2007
Total Posts : 2775
   Posted 11/19/2007 3:11 PM (GMT -6)   
I wouldn't put much faith in the un-refridgerated probiotics at places like CVS, Wal-green and Walmart etc. ... the bacterial count is very low to begin with and the shelf life poor. You're better off either getting refridgerated stuff from a health food store, or ordering it online and paying for the shipping. The only probiotic that I find seems ok unrefridgerated is Primal Defense (although once I get it home I throw it in the fridge).

An extremely "poor man's" test of probiotic potency is to mix some (a capsule's worth) in with some milk and let it sit overnight and see how much curdling takes place. This is hardly very scientific, but it's better than nothing. You'd probably have to incubate it at 100F+ to get a more accurate test though.
Pancolitis dx'd 1986, full med-free remission 88-97
Flaring or simmering ever since
10 20 17.5 15 12.5 mg pred, 100 mg Imuran
Probiotics (Primal Defense and others), TSO
Turmeric/circumin, fish oil, many vits/minerals
Lower-carb version of Specific Carb Diet (SCD)
 
 
 

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