From everything I'm learning about GERD (I also have Barrett's esophagus) alcohol is one of the trigger foods and increases acid. I'm not sure about interaction with the PPI, but I wouldn't drink it because it would aggravate overall symptoms, plus, like Kitt, I take other medications. I used to enjoy a glass of wine now and then, but have stopped that. Also had to stop my night time chocolate habit! :-(
If I did decide to have a drink on a very special occasion, I would keep it to one. I think 3 might be pushing it. I'd ask your pharmacist about interaction with the meds.