I noticed your post from April 2005 "Managing PPI Side Effects". I am curious if now three years later you have found a solution, or what was the outcome of your situation?
I have been on PPIs for 5 years and they have always worked find with none (or very little) side effects. However, three months ago I developed side effects: Ringing in ears, then light headedness, then shortness of breath. The side effects stopped after I ceased the PPI.
Working with my doctor, I have tried all the current ones, in standard and 1/2 doeses. And the same thing happens, when I start the side effects start, when I stop the side effects go away. And like you when I stop the PPI the symptoms of GERD return.
I am currently starting 40mg Famotidine PM with 20mg AM, and may increase to 40mg Famotidine 2X daily. All these trials, starts, stops, symptoms, side effects are driving me crazy and greatly affect my livelyhood. (It's hard to go to the gym when acid is creeping up my esophgus).
Several years ago, the PPI (Aciphex) I was taking suddenly did not work as well, and I also had severe gastritis which took me to ER but no diagnosis. Now thinking back, I think it was the PPI that caused the gastritis, as it re-occured several times after that.
At that time I did see a GI specialist who was hell bent on surgery. But thankfully (I think) the endoscopy showed good splincher and no Barrett's. So I was instructed to continue PPIs. And I have until now where my body can't seem to tolerate them.
So I am hoping you can share what was your outcome? Did you find a solution? Thank you.