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hisfaithful1
Regular Member


Date Joined May 2010
Total Posts : 167
   Posted 8/17/2010 10:01 PM (GMT -6)   
Do any of you take Tramadol for pain? If so has it caused muscle twitching or jerking? At first I had the twitching, but now its actually big jerks!  I'm wondering if I should go off of it?   Thanks, Debbie

Alcie
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Date Joined Oct 2009
Total Posts : 3398
   Posted 8/19/2010 9:03 AM (GMT -6)   
It sounds like you are getting the first effects of serotonin syndrome. That's the way mine starts out all the time. And yes, I get it even with just a little too much tramadol.

No you don't have to go off it, just reduce the dose.

But are you taking something else with it, or even on the same day? That's where we usually get in trouble. If you look up serotonin syndrome there are nicelists of the meds not to mix. Wiki has a particularly good explanation and good list. But the lists are not all-inclusive. I've had problems with mising newer meds that aren't on the lists yet. Serotonin syndrome can be life-threatening if you let it get to the point of not being able to control your body temperature. I got that once with a mix of tram and Flexeril. At least I recognized it and stopped both meds. (I'm back on tramadol.)
Alcie
 
 

shanadine
Regular Member


Date Joined Aug 2010
Total Posts : 48
   Posted 8/20/2010 11:09 PM (GMT -6)   
hi i just wanted to let you no, i was on tramadol slow release for about 8 months,the dose was gradually increased until i was on 400mg per day.i was still in a lot of pain and i noticed i started to get slight jerks in all different areas of my body.as the tramadol was increased the jerky movements did get worse but i never put it down to the meds.i did then start to pass out suddenly and without any warning.i got some nasty bumps on my head and hurted my shoulder very badly due to this. i thot it was another symptom of my fibro (as i im still learning about fibro ).when i told the dr at the pain clinic i was taken off the tramadol right away. the dr said ii shouldv told him about the jerky movements soon as they started as the tramadol was the def cause! the twiching started slightly in my face then my arms and so on,i just didnt even think for a min it could be the tramadol. the doc said some people got this with tramadol and its got to be stopped a.s.a.p when this happens. i dont mean to frighten you,but i dont want you to end up as bad as i was. ithink you should let your dr know about this. the jerky movements are quite scary arent they and also annoying.

i hope this helps you a little debbie,i think its worth getting it cheked out.
we all react different to meds, you may only have to reduce the dos as alcie says but please ask your dr first and dont just do it yourself.
when i stopped the tramadol the jerky movements stopped after about 2weeks and so did the blackouts. i wish you all the best ,
s.

Alcie
Veteran Member


Date Joined Oct 2009
Total Posts : 3398
   Posted 8/21/2010 9:38 AM (GMT -6)   
Shana-
I react to tramadol alone in higher amounts, but I'm fine if I keep it to 100 - 150 mg/day.

Were you taking anything else at the time? Tramadol reacts with just about everything.
Alcie
 
 

shanadine
Regular Member


Date Joined Aug 2010
Total Posts : 48
   Posted 8/21/2010 11:34 PM (GMT -6)   
hi alcie, yes i was also taking do-drydamol 30/500. 8 per day. i still take these with the butrans patch although not 8 most days 4-6 a day. the thing you mentioned - serotonin syndrom iv never heard of this. is it due to too many pain killers or is it a certain type of pain med, it does sound a frightening thing. thanks shanadine

hisfaithful1
Regular Member


Date Joined May 2010
Total Posts : 167
   Posted 8/23/2010 8:00 AM (GMT -6)   
 
 
 
 
          Thanks for the replys. 
 
   Gee here I have been taking
Tramadol 200mgs a day, plus Flexeril at night. Shanadine what you went through sounds awful, it's a wonder you didn't really hurt yourself even worse!I appreciate you sharing, thanks so much.
 
I guess I need to talk to my doctor.
 
 Alcie, I read alot about tramadol awhile back and only one site mentioned Tramadol can cause muscle twitches. So I thought ok, this is a normal side effect of it. The twitches are now pretty bad jerks all over. Every single muscle in my body has beened jerked.  Lol  Even my fingers and toes. should'nt have my doctor have at least warned me about taking the flexeril with tramadol?
 
Shanadine,I am afraid my doctor will not give me a pain med to replace the tramadol that will work as well, I too have Fibro and the tramadol really helps.
I guess I'll find out.  I'll let you know after I see my doctor.
 
Blessings, Debbie
 
  

stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32599
   Posted 8/23/2010 10:46 AM (GMT -6)   
Link to great info on serotonin-syndrome.  You will see in the info the many different drugs that may cause this syndrome.  Just click on the link.  :-)
http://www.mayoclinic.com/health/serotonin-syndrome/DS00860
~~Kitt~~
Moderator: Anxiety/Panic, Osteoarthritis, GERD/Heartburn and Heart/Cardiovascular Disease.
www.healingwell.com

"If you can't change the world, change your world"

hisfaithful1
Regular Member


Date Joined May 2010
Total Posts : 167
   Posted 8/23/2010 8:40 PM (GMT -6)   
 
 
                 Stkitt,    Thanks so much for the link.
 
 I checked it out, and it was really helpful, especially since I am seeing my doctor tomorrow. I will be asking him to change two of my meds. I'll let you know how it goes.    
 
   Blessings, Debbie S 

stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32599
   Posted 8/24/2010 9:20 AM (GMT -6)   
Debbie,

Glad you found the link helpful. It is good to understand serotonin-syndrome and I am  glad to read you are going to talk with your physician re your issues.

Keep us posted.

Kindly,
Kitt
~~Kitt~~
Moderator: Anxiety/Panic, Osteoarthritis, GERD/Heartburn and Heart/Cardiovascular Disease.
www.healingwell.com

"If you can't change the world, change your world"

Alcie
Veteran Member


Date Joined Oct 2009
Total Posts : 3398
   Posted 8/24/2010 6:40 PM (GMT -6)   
Muscle twitches are NOT a normal reaction to tramadol. They are the first warning that you are getting serotonin syndrome. After that comes the whole body twitches/seizures, then you lose control of your body temperature and you need medical treatment fast.

If you start getting twitches you need to cut down the tramadol, or stop taking it or the snri or whatever you are taking with it. You can do a search easily for tramadol and X. Or go to drugs.com and search for drugs that don't go together there.
Alcie
 
 

stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32599
   Posted 8/25/2010 10:06 AM (GMT -6)   

Alcie,

The link I posted gives indepth info re serotonin syndrome.  Serotonin syndrome generally doesn't cause any problems once serotonin levels are back to normal. But if left untreated, severe serotonin syndrome can lead to unconsciousness and death.

Anyone with these sx should see their  physicians or present to the ER.  

Treatment of serotonin syndrome depends on the severity of your symptoms.

  • If your symptoms are minor, a visit to the doctor and stopping the medication causing the problem may be enough.
  • If you have symptoms that concern your doctor, you may need to go to the hospital. Your doctor may have you stay in the hospital for several hours to make sure you're OK.
  • If you have severe serotonin syndrome, you may need additional medications and longer hospitalization. reference Mayo Clinic

Just my 2 cents for today. :-)


~~Kitt~~
Moderator: Anxiety/Panic, Osteoarthritis, GERD/Heartburn and Heart/Cardiovascular Disease.
www.healingwell.com

"If you can't change the world, change your world"

Alcie
Veteran Member


Date Joined Oct 2009
Total Posts : 3398
   Posted 8/29/2010 8:19 PM (GMT -6)   
Kitt -
Right! I was unclear in recommending stopping the drug that one should call or visit the doctor. Of course you call the doctor! If you can't get hold of him, go to the ER if symptoms are really bad.

I think that we should all read about our medications, and a lot of us don't.

I just seem to keep getting the symptoms from even a little too much tramadol without anything else. For me that can be only 3 pills in a day sometimes, and I just cut back and am OK.

I like the explanation of serotonin syndrome on the wikipedia also.
Alcie
 
 

applevenus
Veteran Member


Date Joined Aug 2011
Total Posts : 934
   Posted 7/9/2012 5:23 PM (GMT -6)   
I realize I am resurrecting a really old post by commenting, so I hope you won't mind too badly! I am usually active on the Fibromyalgia forum here at HealingWell.

I am dumbfounded why my rheumatologist put me in Tramadol and Flexeril at the same time. She prescribed them together and never said that they should not be taken together.

Most of the time though, I do not take them together. Occasionally, I feel muscle pain so bad I will take both at night. They help me sleep pretty well -- usually -- but last night I awoke from jerking and twitching all through the night so that's how I ended up here.

I think I will read up more on Serotonin Syndrome now. Thanks for the good info!

Dixiespeed
New Member


Date Joined Jul 2012
Total Posts : 2
   Posted 7/11/2012 4:49 PM (GMT -6)   
I have been taking Ultram for about 10 years. I went from 1 a day to 2 then to 4 a day. If i miss one dose or get close to time for another dose, I will get the jerks. I missed 2 days of it and thought I was going to lose my mind. Impossible to sit still. I got into bed I was so tired and every part of me jerking, no way to sleep. I took the regular dose and calmed down. I have not had a natural feeling since I have been on this stuff. I always feel like I am high. I hate the feeling. What should I do? I talked to the doctor that is giving me this stuff and she says that it is not habit forming. I would say that was a lie.
 
 
 

stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32599
   Posted 7/12/2012 1:21 PM (GMT -6)   
 
I do not know what doses you have been prescribed of Tramadol and Flexeril, however, I would advice you to call your pharmacist to see if these 2 meds at the dose prescribed are safe to take together ?  If your pharmacists says no then do contact your Dr. 
 
 
Hello and thank you for posting.  I am sure you know this so bear with me - Ultram (tramadol) is a narcotic-like pain reliever. Ultram can be habit forming and withdrawals sx are very similiar to withdrawing from some of the major narcotics or antidepressants.  I agree, your Dr. is reciting what she has been told by the Pharm company.  Also this is not a drug you want to just stop taking "cold turkey".  Perhaps it is time to see a physician with a background in helping people wean off of this type of medication. 
 
This may be a site you will find helpful.
On-line drug weaning information: (to be used in conjunction with, not substitution for your doctor's instructions)
 
I wish each of you peace,
Kitt


~~Kitt~~
Moderator: Anxiety, Osteoarthritis,
GERD/Heartburn and Heart/Cardiovascular Disease.



"I am not afraid of storms for I am learning how to sail my ship" ~ Louisa May Alcott

Dixiespeed
New Member


Date Joined Jul 2012
Total Posts : 2
   Posted 7/13/2012 3:01 PM (GMT -6)   
Thank you stkitt
You seem to be very knowledgeable about meds. I thought maybe I should show you what all I am taking and maybe you can tell me why I have the shakes and tremors so bad. I wish I could get off all meds but i know that is not possible. I am 60 year old male with osteoarthritis, lupus and you can tell by the meds some other conditions.

Celebrex 200 mg
Voltaren Gel
Tramadol HCL 100 mg (50 mg X 2)
Metformin 500 mg
Benazepril HCTZ 20 12.5 mg
Ropinerol (Requip) 1 mg
Bystolic 20 mg
Potassium Citrate ER 10 meq
Lansoprazole (Prevacid) 30 mg
Venlafaxine HCL (Effexor) XR 150 mg
Osteo Bi-flex
Morphine
Amlodipine (Norvasc) 30mg
5mg
Testosterone 1 unit
Biotin 5000mg
Demerol 50mg
Cialis 5mg
Vitamin D 50000mg
Vitamin D3 2000iu
Methocarbamol (Robaxin 750mg
I have found out it is not good to mix tramadol with effexor.

stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32599
   Posted 7/18/2012 8:00 PM (GMT -6)   
Hey there,
 
That is quite a list and longer than mine.  I hear you when you say you would like to get off of all of them.  My exact sentiments re my own meds.
 
Twitches, shakes and tremors are often symptoms of conditions or diseases,   but could also be side effects associated with certain medications. Please remember I am not a Dr. and do contact your's if you continue to have these symptoms.
 
Effexor is an antidepressant used to treat depression and anxiety. It is a serotonin-norepinephrine reuptake inhibitor (SNRI). This one I take and I know first hand how some of the side effects feel. 
 
Demerol can cause muscle twitching and tremors.
 
Tramadol can affect the central nervous system and cause tremors, anxiety, muscles spasms, hallucinations and emotional changes.
 
Shaking, twitching,  muscle spasms or body tremors are all associated with Morphine.   
 
Although Requip reduces tremors, it may increase tremor in certain patients.   
 
I am sure you have realized you may be in a catch 22 with your meds, Dixie, as you obviously need to control your symptoms from your disease and disorders yet your list is extremely long and knowing which medications are the culprit will be hard to figure out.  Talk with your Dr. about taking away one at a time and if that is the one causing the problem.  
 
I wish I had better advice and my heart goes out to you as I have often sat down and cried when I realize I take 10 different meds daily. 
 
Take care and know we are here to support you.
 
Kindly,
Kitt
 
 
 
~~Kitt~~
Moderator: Anxiety, Osteoarthritis,
GERD/Heartburn and Heart/Cardiovascular Disease.



"I am not afraid of storms for I am learning how to sail my ship" ~ Louisa May Alcott

pocketfull
Regular Member


Date Joined Mar 2012
Total Posts : 350
   Posted 7/31/2012 11:48 AM (GMT -6)   
Many times the meds we take are actually very dangerous when taken with other meds. I found out the hard way with xanax and gabapentin. I took xanax as needed and just a .05 mg worked fine. Usually didnt take over twice a week. When I started gabapentin I didnt have any problem at all, taking xanax very little. It was Xmas week and a house full of people, children to seniors for nearly a week. I HAD to take xanax every day, sometimes more than one. Well, I had swelling on my face, mainly my lips. I didnt feel any internal swelling. The week after I was just exhausted and hurting so bad. I took 1 xanax a day that week to help me take a nap. Well, on saturday my husband was away all day. When he got home I had swollen on my entire face. Eyes swelled shut, ears swollen, lips swelled at least 5 times normal size. My neck was swollen down to my shoulders. Had I swollen in my throat as quickly as my face did, I would have died. My tongue swelled just a little bit. I was VERY LUCKY. I was also very stupid because I should have gone to emergency room. It turned out that when I took the xanax so that I had a build up of it, then it and the gabapentin did not work together. I stopped the xanax for good, forever. My doctor then gave me valium. I take it 3 times a day, very low dose. It works well. I have never had any swelling at all.

Post Edited (neuropathy10) : 7/31/2012 10:52:33 AM (GMT-6)


lawork1211
New Member


Date Joined Jul 2013
Total Posts : 1
   Posted 7/21/2013 9:52 AM (GMT -6)   
How long after you are off tramadol do the muscle spasms last? I have been off for more than a week and are still having the spams. I was only taking antivert (as needed) and tramadol (as needed). Antivert maybe 3 times a week and tramadol maybe once a day, or on rare bad days two (at lowest dosage pill), some days not at all.
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