Has anyone tested you for Mastocytosis? Gastrcrom is the primary medication used to treat it ~ it's a mast cell stabilizer, so it basically prevents antibodies from activating the allergic response.
And have you been worked up for CMV, EBV, HSV, etc.? Sometimes, systemic viral infections can cause chronic hives/angioedema.
Also, if the doctor is willing to draw blood and do the allergy tests that way (i.e., by measuring IgE responses to specific test substances), then you may be able to get tested without having to go off the anti-allergy medications. My husband has been on steroids for a long time for his food allergies, and his RAST blood tests always show plenty of reactivity against the foods he is allergic to, so I know the blood test method can be an alternative to skin prick/scratch tests.
I hope this helps - take care,
Gluten & Sulfite Sensitivity, Many Food/Inhalant/Medication Allergies & Intolerances, Asthma, Gut issues (dysmotility, non-specific inflammation), UCTD (Lupus?), Osteoporosis, Anemia, T- & B-Cell Lymphopenia, malabsorption/malnutrition, Lyme Disease (Igenex Lab IgM WesternBlot positive/CDC negative), etc.; Currently TPN-dependent.
Meds: Pulmicort, Zofran, Scopalamine Patch, Injectable Vitamin B12, Heparin (to flush PICC line).