Inositol and panic disorderDouble-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. Ben Gurion University of the Negev, Beer-Sheba, Israel.J Clin Psychopharmacol. 2001 Jun;21(3):335-9.Myo Inositol, a natural isomer of glucose and a precursor for the second-messenger phosphatidyl inositol system, has previously been found superior to placebo in the treatment of depression, panic disorder, and obsessive-compulsive disorder OCD, but a direct comparison with an established drug has never been performed. A double-blind, controlled, random-order crossover study was undertaken to compare the effect of inositol with that of fluvoxamine in panic disorder. Twenty patients completed 1 month of inositol up to 18 grams a day and 1 month of fluvoxamine up to 150 mg/day. Improvements on Hamilton Rating Scale for Anxiety scores, agoraphobia scores, and Clinical Global Impressions Scale scores were similar for both treatments. In the first month, inositol reduced the number of panic attacks per week by 4 compared with a reduction of 2.4 with fluvoxamine. Nausea and tiredness were more common with fluvoxamine. Because inositol is a natural compound with few known side effects, it is attractive to patients who are ambivalent about taking psychiatric medication.
Since many antidepressants are effective in panic disorder, twenty-one patients with panic disorder with or without agoraphobia completed a double-blind, placebo-controlled, four week, random-assignment crossover treatment trial of inositol 12 grams per day. Frequency and severity of panic attacks and severity of agoraphobia declined significantly with inositol compared to placebo. Side-effects were minimal. Since serotonin re-uptake inhibitors benefit obsessive compulsive disorder OCD and inositol is reported to reverse desensitization of serotonin receptors, thirteen patients with OCD completed a double-blind controlled crossover trial of 18 g inositol or placebo for six weeks each. Inositol significantly reduced scores of OCD symptoms compared with placebo.
If a member is already on medications for their dx would they have to stop the med they are taking to know if trying this chemical compound is working for them?
I did review the sites but it reads a lot like chemistry class which is above my head. I did understand the part re double blind study.
Thank you Kitt
This really does get technical doesn't it?! I think we all should be open to trying new things for our anxiety treament..everybody is individual and we all need different treatments.
Thanks Peacesoul for finding this one
I have to agree on that one Peacesoul!
I love my pharmacist, I trust her so much more than my doctor. Whenever I get a new script I take it in and discuss it with her, she knows my history better than my doc and she knows which meds will "clash". Best of all she is there 7 days a week and her advice is free. A relationship with your pharmacist is absolute gold.
EmmaT, it is nice to see you here with us. Welcome to HealingWell. We are a peer support group.
I do not have the information but I do think you should ask your physician as they can find the answer for you and each person uses a different BC med. Yes medical pysicians can and many are very knowledgable about natural supplements as many people take them.
Support groups are a place for people to give and receive both emotional and practical support as well as to exchange information. People with health conditions, as well as their friends and families find support groups to be a valuable resource and get confirmation that their feelings are "normal", educate others, or just let off steam.
Again, welcome to HW.