Inositol For Anxiety and Depression

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peacesoul
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Date Joined Jan 2007
Total Posts : 2446
   Posted 1/13/2009 3:48 PM (GMT -7)   
Has anyone heard of this or tried it?
 
I just saw a entire medical show on this. Looks promising. I'm going to try it
 
 
 
 
 

Inositol and panic disorder
Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder.

 Ben Gurion University of the Negev, Beer-Sheba, Israel.
J Clin Psychopharmacol. 2001 Jun;21(3):335-9.
Myo Inositol, a natural isomer of glucose and a precursor for the second-messenger phosphatidyl inositol system, has previously been found superior to placebo in the treatment of depression, panic disorder, and obsessive-compulsive disorder OCD, but a direct comparison with an established drug has never been performed. A double-blind, controlled, random-order crossover study was undertaken to compare the effect of inositol with that of fluvoxamine in panic disorder. Twenty patients completed 1 month of inositol up to 18 grams a day and 1 month of fluvoxamine up to 150 mg/day. Improvements on Hamilton Rating Scale for Anxiety scores, agoraphobia scores, and Clinical Global Impressions Scale scores were similar for both treatments. In the first month, inositol reduced the number of panic attacks per week by 4 compared with a reduction of 2.4 with fluvoxamine. Nausea and tiredness were more common with fluvoxamine. Because inositol is a natural compound with few known side effects, it is attractive to patients who are ambivalent about taking psychiatric medication.

Since many antidepressants are effective in panic disorder, twenty-one patients with panic disorder with or without agoraphobia completed a double-blind, placebo-controlled, four week, random-assignment crossover treatment trial of inositol 12 grams  per day. Frequency and severity of panic attacks and severity of agoraphobia declined significantly with inositol compared to placebo. Side-effects were minimal. Since serotonin re-uptake inhibitors benefit obsessive compulsive disorder OCD and inositol is reported to reverse desensitization of serotonin receptors, thirteen patients with OCD completed a double-blind controlled crossover trial of 18 g inositol or placebo for six weeks each. Inositol significantly reduced scores of OCD symptoms compared with placebo.


The world breaks every one and afterward many are strong in the broken places


stkitt
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Date Joined Apr 2007
Total Posts : 32602
   Posted 1/13/2009 3:57 PM (GMT -7)   

Peacesoul,

If a member is already on medications for their dx would they have to stop the med they are taking to know if trying this chemical compound is working for them?

I did review the sites but it reads a lot like chemistry class which is above my head. I did understand the part re double blind study.

Thank you
Kitt



 

Kitt, Co-Moderator: Anxiety/Panic & Depression
&  Moderator GERD  Forums

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Peace does not dwell in outward things, but within the soul
Clickable Link: Anxiety-Panic Resources


peacesoul
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Date Joined Jan 2007
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   Posted 1/13/2009 4:04 PM (GMT -7)   
I'm not sure. I would have to read more about it.
I would think it would be fine since this is a compound that is already produced by the body and is also in cantelope, wheat, bananas and other foods.
I read that this is found in everyone, but those who have OCD, depression, anxiety etc have a lack of this compound in their spinal fluid.

You cannot overdose and there are no side effects since it's already part of our chemical make up
The world breaks every one and afterward many are strong in the broken places


nervymeg
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Date Joined Jul 2006
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   Posted 1/13/2009 4:20 PM (GMT -7)   

Goodness,

This really does get technical doesn't it?! I think we all should be open to trying new things for our anxiety treament..everybody is individual and we all need different treatments.

Thanks Peacesoul for finding this one wink

Meg


Co-moderator Anxiety/Panic
Panic Attack Survivor
 


Green Grove
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Date Joined Oct 2008
Total Posts : 2424
   Posted 1/13/2009 5:14 PM (GMT -7)   
Very interesting Peacesoul. . . Definitely something to think about for those that are working on different treatments with their physicians and therapist :)
Take care and have a wonderful day! . . . Your Bro . . . Sam :)
 ~Co-Moderator Anxiety & Panic Forum~
  "When you come to the end of your rope, tie a knot and hang on."
~Franklin D. Roosevelt~
Not a professional.  Seek your physician's advice before making changes to your meds or lifestyle.
 


peacesoul
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Date Joined Jan 2007
Total Posts : 2446
   Posted 1/13/2009 6:40 PM (GMT -7)   
this seems like a good site for info
 
 
I would not even bother asking a dr about this unless the dr has a background or knowledge of natural health. An ND is also a medical dr with a background in natural and conventional medicine so they would prob be the best person to ask. Or a pharmacist. A pharmacist has a lot more knowledge of meds than a dr.
 
 

 
 
 
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dx with lupus and lyme disease in 2007. Treated for lyme for 5 months with abx. Now treating my lyme and lupus (I believe lyme caused the lupus) 100% naturally
 
The world breaks every one and afterward many are strong in the broken places


nervymeg
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Date Joined Jul 2006
Total Posts : 2721
   Posted 1/13/2009 8:26 PM (GMT -7)   

I have to agree on that one Peacesoul!

I love my pharmacist, I trust her so much more than my doctor. Whenever I get a new script I take it in and discuss it with her, she knows my history better than my doc and she knows which meds will "clash". Best of all she is there 7 days a week and her advice is free. A relationship with your pharmacist is absolute gold.

Meg 


Co-moderator Anxiety/Panic
Panic Attack Survivor
 


EmmaT
New Member


Date Joined Feb 2009
Total Posts : 2
   Posted 2/1/2009 3:38 PM (GMT -7)   
I have been looking into B vitamin inositol as well for nail and skin picking reasons. I did read a good article from a Doctor on Inositol and Trich. I have a couple websites if you would like to look into them if you are wanted to take it for the same reasons.

I did have a question that I'm hoping you could answer since you look to be doing a lot of information. I was wondering if it counteracts with an oral contraceptive. I am not sure if this vitamin is suppose to work like St. John's Wort or not. I have also seen in research that it can control estrogen levels as well. So I just want to make sure if I start to take this, it would increase any chances for me getting pregnant!

If you know anything or know how to find out this information I would really appreciate it.

stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32602
   Posted 2/1/2009 4:19 PM (GMT -7)   

EmmaT, it is nice to see you here with us. Welcome to HealingWell. We are a peer support group.

I do not have the  information but I do think you should ask your physician as they can find the answer for you and each person uses a different BC med. Yes medical pysicians can and many are very knowledgable about natural supplements as many people take them.

Support groups are a place for people to give and receive both emotional and practical support as well as to exchange information. People with health conditions, as well as their friends and families find support groups to be a valuable resource and get confirmation that their feelings are "normal", educate others, or just let off steam.

Again, welcome to HW.

Kitt

 


 

Kitt, Co-Moderator: Anxiety/Panic & Depression
&  Moderator GERD  Forums

*~*
http://www.healingwell.com/donate *~*
Not a mental health professional of any kind
Peace does not dwell in outward things, but within the soul
Clickable Link: Anxiety-Panic Resources


patzy
New Member


Date Joined Feb 2009
Total Posts : 3
   Posted 2/14/2009 7:05 PM (GMT -7)   
I just took 13 grams. (the bottle has capsules with 650 mg per cap. so that is as close to 12 grams as I could get.)
I was researching online and came across your post. Have you tried Inositol yet? If so, results?
 
What tv program did you see the Inositol subject on?
 
Any idea if the doses should be broken up over the day or ???
 
I'm so desperate I just took the whole 13 grams sublingually. (broke open the caps) Thank goodness Inositol is sweet. smilewinkgrin

EmmaT
New Member


Date Joined Feb 2009
Total Posts : 2
   Posted 2/26/2009 9:16 PM (GMT -7)   
patzy....please read these websites for more info on dosage. this is what im going to guide myself by so you dont have to be concerned on how much to take or if you took too much which wont hurt you as far as I know

http://westsuffolkpsych.homestead.com/inositol.html

hope this helps

patzy
New Member


Date Joined Feb 2009
Total Posts : 3
   Posted 2/26/2009 10:12 PM (GMT -7)   
Thanks so much! Very informative. yeah
Now to find a good source of good quality affordable shocked inositol if I do need to go up to 18 grams.
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