Well I have had a complete hysterectomy myself, but can attest to the fact that when I did have my monthly, I was either in a complete rage or really depressed. So yes, it did affect me. As for the Zoloft, it takes 4-6 weeks to reach full effect, so I think you need to continue to give it some more time.
Gail*Nanners* Co-Moderator for Crohns Disease and Anxiety/Panic Forum
Crohn's Disease for over 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium w/Vit D, and Xanax as needed. Resections in 2002 and 2005. Also diagnosed with Fibromyalgia, Osteoarthritis, and Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
It's scary when you start making the same noises As your coffee maker.
*Every tomorrow has two handles. We can take hold of it by the handle of anxiety, or by the handle of faith"*