Xanax duration of calming feeling

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pharcyder
Regular Member


Date Joined May 2012
Total Posts : 69
   Posted 2/3/2014 9:26 AM (GMT -6)   
Hello all,
I currently take 0.5mg of xanax twice daily for anxiety. I have read that the half life of xanax is about 11 hours. However, the duration that the calming effects last can range from 4 to 6 hours. Why is the half- life longer than the duration of effectiveness? I have been unable to find any information on this subject online. Thanks for all the help!!

stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32602
   Posted 2/3/2014 9:46 AM (GMT -6)   
Half-life is the amount of time it takes for the drug's efficacy to deplete 50%. Side effect intensity and duration varies from person to person.
 
If you have a single dose of a medication and the half life is 3 hours, and you only take that single dose, it will be 1/2 gone in 3 hours, 3/4 gone in 6 hours, 7/8 gone in 9 hours, 15/16 gone in 12 hours and 31/32 (or clean blood) in 15 hours.
~~Kitt~~
Moderator: Anxiety/Panic
and Heart/Cardiovascular Disease.



"She Stood in the Storm & When the Wind Did Not Blow Her Away, She Adjusted Her Sails."

pharcyder
Regular Member


Date Joined May 2012
Total Posts : 69
   Posted 2/3/2014 10:23 AM (GMT -6)   
Kitt, Thank you for your response.

If the half life of the medication is 10 hours, should I still theoretically feel half of the effect from that medication (Xanax) 10 hours after I take it?

stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32602
   Posted 2/3/2014 11:17 AM (GMT -6)   
Taking your example, regardless of dose, onset of action is between 15-30 minutes with peak effect around 1-2 hours after ingestion. It has an average half life somewhere around 11-12 hours, so the effect can last anywhere from 6-12 hours. A higher or lower dose will change strength of the effect, but not really the duration of action. I hope this helps.                 
~~Kitt~~
Moderator: Anxiety/Panic
and Heart/Cardiovascular Disease.



"She Stood in the Storm & When the Wind Did Not Blow Her Away, She Adjusted Her Sails."

pharcyder
Regular Member


Date Joined May 2012
Total Posts : 69
   Posted 2/3/2014 11:20 AM (GMT -6)   
Kitt, thank you. This medication is a life saver. I wish I was prescribed Xanax 10 years ago.

Bella33
Regular Member


Date Joined Aug 2008
Total Posts : 478
   Posted 2/3/2014 1:47 PM (GMT -6)   
Hi,

I've been on half a .25mg Xanax for over 10 years now. As little as the dosage is I can function since I've been on it all these years. When I miss just a day I would get the jitters and vertigo. My family thinks it's all in my head but the only way I would know I missed a dose is when I feel bad so it's not.

I want to go off of it once and for all. How do I wean off? I stopped today and I already feel light headed and out of focus. I usually take it around 6:30am and it's been about 5 hours now and I feel it. Am I just super sensitive?

I used to say I would be on this for life and since I have never increased all these years but still I do not like to depend on a drug and my own doctor is tired of prescribing it to me. She thinks it's a crutch that I should get rid of.

pharcyder
Regular Member


Date Joined May 2012
Total Posts : 69
   Posted 2/3/2014 2:54 PM (GMT -6)   
Xanax is highly addictive. Its best to taper off very slowly. Stopping xanax cold turkey can cause death.

Bella33
Regular Member


Date Joined Aug 2008
Total Posts : 478
   Posted 2/3/2014 3:04 PM (GMT -6)   
Even at the tiny dosage I'm on?

pharcyder
Regular Member


Date Joined May 2012
Total Posts : 69
   Posted 2/3/2014 4:01 PM (GMT -6)   
As a new xanax user, im planning on taking it forever because it helps me.

Bella33
Regular Member


Date Joined Aug 2008
Total Posts : 478
   Posted 2/3/2014 4:05 PM (GMT -6)   
That was my intention too but I don't like to have that hold on me. I should be able to function without it.

groverpower
Regular Member


Date Joined Aug 2012
Total Posts : 183
   Posted 2/7/2014 8:04 AM (GMT -6)   
Hello. I used to take Xanax regularly and weaned off. Even if u have are taking a low dose i would suggest that you wean off to minimize possibility of rebound anxiety. You've been on it for 10 yrs anyway what's another 2 months for weaning? In d grand scheme of things its all good. Peace.

Bella33
Regular Member


Date Joined Aug 2008
Total Posts : 478
   Posted 2/7/2014 8:11 AM (GMT -6)   
Thanks. I tried it for just one day and I gave up. I had heart palpitations and fluttering in my throat area and was a nervous wreck and had body pain all over. I couldn't concentrate at work or follow directions. All this from just one day of missing a half .25 pill. Geez!
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