Unusual Xanax Side Effects

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Green Lantern
Regular Member


Date Joined Apr 2006
Total Posts : 105
   Posted 11/1/2006 11:01 AM (GMT -6)   

I have been experiencing uncharacteristic fits of rage and anger and figured it was from one of my many meds.  Xanax seemed like the least likely candidate until I found information such as the following:

The Production of Mania and Rage As the above observations confirm, reactions to Xanax and other benzodiazepines can reach psychotic proportions. As noted in the 1996 edition of Drug Facts and Comparisons, the BZs in general can cause serious psychiatric problems, including "psychosis." They can disrupt central nervous system function, producing, among other things, "disorientation... confusion... delirium.... euphoria... agitation." A special Precautions section notes "Paradoxical reactions," including "excitement, stimulation and acute rage" and "hyperexcited states, anxiety, hallucinations..." Mania, a psychosis, is a special danger in regard to Xanax. The Drug Facts and Comparisons (p. 1440) makes a specific reference to Xanax in this regard, stating that "Anger, hostility and episodes of mania and hypomania have been noted with alprazolam." The fact that mania is a particular risk with Xanax is generally recognized. As another example, Maxmen and Ward's Psychotropic Drug Fast Facts (1995, p. 287) states that "manic reactions" are "Most often reported with alprazolam." It also states that "rage reactions" and "violent episodes" have especially been observed with Xanax and Valium. Yet another example is The Handbook of Psychiatric Drug Therapy (Third edition, 1995, p. 177) by Hyman, Arana, and Rosenbaum. It singles out Xanax to observe "Increased impulsiveness, euphoria, and frank mania have been reported with alprazolam." Drug Facts and Comparisons, Psychotropic Drug Fast Facts and the Handbook of Psychiatric Drug therapy are intended for ready reference for physicians for the purpose of alerting them to adverse drug reactions they need to be aware of. That all three indicate that mania and uncontrollable rage are special problems with Xanax confirms my own clinical observations that this medication is more apt than many others to produce these hyper-excited, aggressive psychotic states. The FDA's "Safety Review and Evaluation of Clinical Data" by J. Knudsen (1989) for Xanax for panic disorder once again highlighted its tendency to produce mania. It included a review of Xanax-induced mania from the literature. It described several cases of mania produced in the panic disorder clinical studies and offered two tables described 14 cases of hypomania and one of mania. Several attacks developed during the first week of treatment at relatively small doses.

Just want people to be aware that this could happen.

 


Generalized Anxiety Disorder, Depression


Twiggygal
Veteran Member


Date Joined Sep 2006
Total Posts : 924
   Posted 11/1/2006 3:11 PM (GMT -6)   
Well, I take Ativan.

BUT I also take Lexapro.

I had the fits of rage for about a week when my dose was too high on the Lexapro, so I lowered my dose by 5 mgs and am fine.

So the culprit isn't the Ativan (which is a benzo). It was just that I was on too many mgs of Lexapro, and I couldn't walk on that high of a dose, because it was so painful, so I lowered it because of that too. Now the leg pain has subsided. As has the rage.

Twiggygal~
"Be glad of life because it gives you the chance to love and to work and to play and to look up at the stars."

DX: Panic Disorder, Depression, TMJ (Temporomandibular Joint Disorder), Chronic Migraines
 
RX: Ativan/Lorazapam (1 MG a day), Lexapro (15 MG a day), Tylonel for the TMJ and Migraines
 



harry4
Veteran Member


Date Joined Mar 2005
Total Posts : 1449
   Posted 11/1/2006 8:00 PM (GMT -6)   

I would like to know the xanax doses and doses of any  other benzos also taken

worth remembering that benzos are many times safer than the old barbituates and other tranquillisers used before benzos came along


recovered former longtime anxiety and panic attack sufferer and helper of other sufferers  but no training or  qualifications in medicine or psychology, any remarks that may be taken as advice must be confirmed with doctor or other health professional


Green Lantern
Regular Member


Date Joined Apr 2006
Total Posts : 105
   Posted 11/3/2006 1:41 PM (GMT -6)   
2mg 3X day.  No other benzos.  I was also on Lexapro, and thought that might be the problem, but I went off it for a few weeks and still had the rage along with some serious depression. 
Generalized Anxiety Disorder, Depression


bluemeanies
Veteran Member


Date Joined Jun 2004
Total Posts : 1372
   Posted 11/3/2006 3:26 PM (GMT -6)   
I have taken Xanax for many years and never had a problem with rage while on it. It calms me down and works quite well. I have had a problem with rage while on prednisone. 6mg a day seems to be a higher dose, I take .5mg as needed. I have never taken more than 1mg in a day. Drugs react differently with different people. What helps someone may cause problems for another. That is why you need to work with your doctor to see what works for you.

Green Lantern
Regular Member


Date Joined Apr 2006
Total Posts : 105
   Posted 11/3/2006 4:52 PM (GMT -6)   
Yeah, it is a very high dose, which could be the problem, or maybe I'm just weird.  He originally started me off at a much lower dose (.5 3x day, I think), but it didn't even put a dent in my anxiety.  I just kept calling him back and asking if I could up the dosage by .5.  I didn't feel normal until I got to 2mg.
Generalized Anxiety Disorder, Depression

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