Luvox Or Zoloft?

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Regular Member

Date Joined Jan 2007
Total Posts : 119
   Posted 1/2/2007 10:47 PM (GMT -6)   
I have Pure O (no compulsions) OCD.
I had a great run on Prozac for 17 years before it gave out. "Prozac Poop Out". Most of that time I was only on 20 mgs. Sometimes up to 40. It was GREAT. Went months with near ZERO symptoms.
In September I switched to Lexapro after going up to 80 mgs of Prozac. Neither have done the trick. In fact 60 and 80 mgs of Prozac made my anxiety much worse. Then 20 mgs of Lexapro just increased the agitation and resulting Obsessions.
At the moment I am tapering off Lexapro. 10 mgs. for a couple of weeks then my Pdoc will switch to another SSRI. We both agree lower doses go a long way with me. That, even though it usually takes higher doses to be effective for OCD.
I have done a lot of web based research. I am very aware that feedback is usually coming from dissatisfied users. So when one judges whether a drug is effective online you have to factor in the fact that people who have had difficulties tend to post. Happy campers don't. BTW, I have seen posts here stating all SSRIs are nearly identical. That is clearly not the case. Prozac worked beautifully for me Lexapro was a bust. Your mileage may vary.
My Doc and I both agree our next choices should be either Zoloft or Luvox. She suggests Zoloft I came up with Luvox. Luvox (generic) is rarely prescribed in the US. However, it is only FDA approved for OCD and sufferers seem to like it. On the other hand, I think the Pdoc prefers what she knows best. Zoloft. I'd love to know what y'all have to say. Luvox or Zoloft? You Luvox users will be few in number so please chime in. Thanks in advance.

Veteran Member

Date Joined Mar 2005
Total Posts : 1449
   Posted 1/3/2007 3:18 AM (GMT -6)   
 since Z and L are both the same SSRI type I suspect neither will help and you need to try antidepressants of different types, there are many
maybe the psych can whip up a cocktail with some augmentation as well
recovered former longtime anxiety and panic attack sufferer and helper of other sufferers  but no training or  qualifications in medicine or psychology, any remarks that may be taken as advice must be confirmed with doctor or other health professional
emails are welcome but do mention healingwell to avoid risk of deletion as spam

Elite Member

Date Joined Jan 2005
Total Posts : 24909
   Posted 1/3/2007 7:08 AM (GMT -6)   
I had tried luvox in the past for OCD and I went off for personal reasons I still do not take ssri's for same reasons
I have and do take fast acting meds such as diazapam or ativan PRN
I do more things now to replacce the meds as I was eating way to many of them IMO
I do CBT relaxation and other things
I think you will find more prozac users here with good results
Please do continue to post and become an active member here
This is a fantastic site with great ppl
As you posted you will get different answers but I would go with what you and your doc do decide but it is good to have the input
You be well and take care
See ya soon and do keep us posted please

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Post Edited (Howlyncat) : 1/13/2007 5:02:44 AM (GMT-7)

Regular Member

Date Joined Apr 2006
Total Posts : 279
   Posted 1/3/2007 3:24 PM (GMT -6)   
Do not have OCD myself, but I know my neighbor does and has excellent results with luvox.  As my doctor told me, it's really a matter of trial and error until the right one is found... wishing you the best!!

Regular Member

Date Joined Jan 2007
Total Posts : 119
   Posted 1/3/2007 5:17 PM (GMT -6)   
Thanks so much for your replies.
I must take issue with Harry4. I do not believe all SSRIs are alike. I had great success with prozac. No success with Lexapro. I want to be gentle and mean this to be constructive. It is bad advice when you say because one SSRI doesn't work then none will. Please explain my success with Prozac and lack of it with Lexapro. My wife had no success with Paxil but is doing great with Wellbutrin. It is trial and error. I don't know of any Pdocs who say if one SSRI fails all will fail to be of help.SSRI's are not the same. How you react depends on each drugs affinity for the 5-HT2C receptors.

Post Edited (porridge) : 1/3/2007 3:20:25 PM (GMT-7)

Regular Member

Date Joined Jan 2007
Total Posts : 119
   Posted 1/13/2007 12:30 AM (GMT -6)   
Starting Luvox tonight. Before bedtime. Supposedly very sedating. I am optimistic after Lexapro let me down. 50 mgs to start for one week. Then 100 mgs.

Regular Member

Date Joined Jan 2007
Total Posts : 119
   Posted 1/16/2007 7:16 PM (GMT -6)   
First few days on Luvox have been a roller coaster.Feel better than ever for a few hours then an anxiety spike kicks in. To be expected in the early stages.
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