New Alternative for Med Selection - rEEG

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Green Lantern
Regular Member

Date Joined Apr 2006
Total Posts : 105
   Posted 5/18/2007 3:30 PM (GMT -6)   
I am making this post to make people aware of an option for med selection, particularly for treatment resistant cases, like mine.  As a brief history, I have had several diagnoses including depression, GAD, bipolar and bipolar mixed.  I have, at different times, and in various combinations taken the following meds:  Zoloft, Wellbutrin, Paxil, Lamactil, Geodon, Xanax, Klonopin, Seroquel, Depakote and Lithium.  The only things that had a positive effect were Xanax, Klonopin and Seroquel; however they still left me with a lot of symptoms.  My pdoc eventually admitted he was stumped and told me about another alternative for med selection; rEEG.
The r stands for referenced, meaning they reference your brain EEG to a database of other brain EEGs.  rEEG uses an outcome database – patients who were treated successfully and unsuccessfully.  They compare your brain EEG to other brain EEGs contained in a database to find similar ones.  The database includes information on what meds work most of the time for people with EEGs similar to yours.  They also look for certain biomarkers that indicate what types of meds you are likely to respond to and those that you may have an adverse reaction to.
I just had my rEEG performed on Tuesday and the results take 2-3 weeks to come in.  I will update this thread after I receive my results with what meds were recommended.  I will also update it for the results of the meds (if any).  The worst part about getting the rEEG is that you have to have a "clean" brain for the test.  This means going off all meds (different periods of time for different meds), no over the counter drugs, no herbs or supplements and the worst part:  no caffeine or nicotine for 15 hours prior to the test.  However, after the test you can resume your meds.  The night before the test, I didn't sleep for one minute.  I ended up being awake for 40 hours straight until I got my Klonopin and Seroquel back.  Hope this information is helpful to someone.

No one knows

Veteran Member

Date Joined Mar 2005
Total Posts : 1449
   Posted 5/18/2007 5:33 PM (GMT -6)   
interesting yeah   I hadnt heard of tiis, do let us know how it all turns out
recovered former longtime anxiety and panic attack sufferer and helper of other sufferers  but no training or  qualifications in medicine or psychology, any remarks that may be taken as advice must be confirmed with doctor or other health professional
emails are welcome but do mention healingwell to avoid risk of deletion as spam

Green Lantern
Regular Member

Date Joined Apr 2006
Total Posts : 105
   Posted 6/11/2007 2:10 PM (GMT -6)   
Got the results back today.  Part of my brain (or my brain in general) is going too fast and causing anxiety and the first thing we need to do is slow it down.  Basically, I do not process one thought at a time, but rather think of everything at once.  The medication suggested for this is Neurontin ( a mood stabilizer).  My understanding is that Neurontin is not very effectvie as a mood stabilizer but my pdoc thought it would be effective for the purpose of slowing my brain down and alleviating my anxiety.  The second part of the analysis kind of threw me off.  While my brain in general is going too fast, the activity in the frontal lobes suggests ADD.  This was explained to me as the whole orchestra is there and playing, but the conductor is asleep.  Once we figure out the proper neurontin dose (calming yet I'm not asleep), we will add Adderall for the ADD.  I will keep you posted and let you know how I respond to the meds.

No one knows

Elite Member

Date Joined Jan 2005
Total Posts : 24909
   Posted 6/11/2007 3:06 PM (GMT -6)   
Thanks for the first post and input

Interesting about your results

PLease do keep us posted

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Date Joined Apr 2007
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   Posted 6/11/2007 5:32 PM (GMT -6)   

Thanks for your sharing and it is interesting. Please keep us posted.

I hope you get your meds working and life begins to feel better for you.


Moderator Anxiety ~ Panic Disorders
Dx: Anxiety/Panic, Depression 
"If you doubt you can accomplish something, then you can’t accomplish it. You have to have confidence in your ability, and then be tough enough to follow through.” 
~Rosalyn Carter

Green Lantern
Regular Member

Date Joined Apr 2006
Total Posts : 105
   Posted 6/13/2007 5:51 PM (GMT -6)   

Here is some information on Neurontin (gabapentin):

Gabapentin has had been successful in controlling rapid cycling and mixed bipolar states in a few people who have not received adequate relief from carbamazepine and/or valproate. It also appears that gabapentin has significantly more antianxiety and antiagitation potency than either carbamazepine or valproate. Gabapentin also may be useful as a treatoent for people with antipsychotic-induced tardive dyskinesia.

It's too early to tell if its helping or not, but they are not kidding about sleepiness being a side effect.  I am up to 300mg 3x day and the target is 600mg 3x day.  This stuff knocks me out like Seroquel; however, this is supposed to diminish over time.  I guess I can say it is helping a little bit.  I had severe agitation and this seems to have lessened somewhat.  My major symptoms are severe anxiety and agitation so based on the information I posted above this seems to have some promise.  Will update as the dosage increases.  Thanks for letting me share, no one I know in real life has a clue about this stuff.


No one knows

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