How to prolong the alprazolam half-time? Is omeprazole helpful?

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Licho
Regular Member


Date Joined Jun 2007
Total Posts : 98
   Posted 6/10/2007 11:49 AM (GMT -6)   
Hi everybody, :-)

I'd like to find out if omeprazole (a stomach proton-pump inhibitor drug; as it is metabolised by the cytochrome P450 enzymes) influences on the alprazolam (aka Xanax) half-time and its effect. I have tried 20 mg of omeprazol and 0,5 mg of alprazolam, but I wonder if possible (not so marked) increase of the effect was only an autosuggestion, or real impact. confused

I ask because if it's so, then I could take less tablets of this cure to get desired effect; I would like to save the tablets as it is not very easy to get this cure - doctors but prescribe such ones so unwillingly, although I personally have the social anxiety problems. sad

The most interesting doses for me are 0,5 or 0,75 mg of alprazolam and 20 mg of omeprazole.

Has anyone here tried it?

Or, if it doesn't work, maybe there are some other natural, and safe of course, ways to prolong the alprazolam half-time and concentration in the blood, and maybe you know about some of them? (Maybe the casual carton grapefruit juice, but it's told somewhere it's no impact... eyes

Cheers to you!


I have nothing to add.

Post Edited (Licho) : 6/12/2007 12:13:26 AM (GMT-6)


stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32602
   Posted 6/10/2007 2:27 PM (GMT -6)   

Licha

Hello and welcome as a new member to Healing Well.  I have read this post and also your other posts.

The 2 drugs you mention here, Xanax for anxiety and Prilosec for GERD or acid indigestion are prescribed for specific reasons and Prilosec is now easily available over the counter.

Do I think you should be trying to work out half lifes of drugs etc..........no.  Everyone metabolizes drugs at different rates as well as some are metabolized through the liver and others excreted in urine.

I would not want any of our members to even consider the possibility of manipulating thier drug dosing in this manner. 

This is my 2 cents worth yeah

Again Welcome.

 

 



Respectfully
Kitt
Moderator Anxiety ~ Panic Disorders
Dx: Anxiety/Panic, Depression 
______________________________________________________
"If you doubt you can accomplish something, then you can’t accomplish it. You have to have confidence in your ability, and then be tough enough to follow through.” 
~Rosalyn Carter

Post Edited (stkitt) : 6/16/2007 7:43:49 AM (GMT-6)


harry4
Veteran Member


Date Joined Mar 2005
Total Posts : 1449
   Posted 6/10/2007 3:38 PM (GMT -6)   

I would be asking a pharmacist to look this uo for you , try your usual one first

ironically grapefruit is said to alter xanax


recovered former longtime anxiety and panic attack sufferer and helper of other sufferers  but no training or  qualifications in medicine or psychology, any remarks that may be taken as advice must be confirmed with doctor or other health professional
emails are welcome but do mention healingwell to avoid risk of deletion as spam


Licho
Regular Member


Date Joined Jun 2007
Total Posts : 98
   Posted 6/12/2007 1:20 AM (GMT -6)   
stkitt said...

Licha

Hello and welcome as a new member to Healing Well.  I have read this post and also your other posts.

The 2 drugs you mention here, Xanax for anxiety and Prilosec for GERD or acid indigestion are prescribed for specific reasons and Prilosec is now easily available over the counter.

Do I think you should be trying to work out half lifes of drugs etc..........no.  Everyone metabolizes drugs at different rates as well as some are metabolized through the liver and others excreted in urine.

I would not want any of our members to even consider the possibility of manipulating thier drug dosing in this manner. 

This is my 2 cents worth yeah

Again Welcome.

 

 

 
Well, I only interest myself in pharmacology a bit... :-)
But I take my alprazolam very rarely - only really occasionally - so that's why I consider possible mild interactions. I obviously don't suppose anybody to "playing" with their everyday dosage, as I know some people get the benzodiazepines daily.
Cheers!

Post Edited By Moderator (stkitt) : 6/16/2007 7:43:25 AM (GMT-6)


Howlyncat
Elite Member


Date Joined Jan 2005
Total Posts : 24909
   Posted 6/12/2007 6:23 AM (GMT -6)   
It would be best to talk to your doc or pharmacist about this
I would not do this on my own
Just my half cent worth
Welcome aboard ......STAY with us please


LYN
    Contribute today to support Healing Well Forums...Donate @
 
Co Mod ..Crohns Forum
Moderator .......A/P Forum
Moderator ....Alzheimers Forum 
 
DX with Crohns, Pyoderma Gangrenosum,Anxiety /Panic
 
Take my Hand ...I will WALK with you
 
When the GOING gets TOUGH..The TOUGH get GOING 
 
 God Bless All
 
LYN    
                                  


Licho
Regular Member


Date Joined Jun 2007
Total Posts : 98
   Posted 6/16/2007 5:29 AM (GMT -6)   

OK

Thanks :-)


I have nothing to add.


Howlyncat
Elite Member


Date Joined Jan 2005
Total Posts : 24909
   Posted 6/16/2007 8:26 AM (GMT -6)   
Keep us posted........plz......

LYN
    Contribute today to support Healing Well Forums...Donate @
 
Co Mod ..Crohns Forum
Moderator .......A/P Forum
Moderator ....Alzheimers Forum 
 
DX with Crohns, Pyoderma Gangrenosum,Anxiety /Panic
 
Take my Hand ...I will WALK with you
 
When the GOING gets TOUGH..The TOUGH get GOING 
 
 God Bless All
 
LYN    
                                  


stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32602
   Posted 6/16/2007 8:41 AM (GMT 0)   

Dear Licho,

I did not mean to sound so stern. I was concerned re your post that you might get into serious problems and perhaps exacerbate your condition by looking at half life of a combo of drugs.

I apologize if I misunderstood your post. yeah

Please stay with us and keep posting. Your family now.


Respectfully
Kitt
Moderator Anxiety ~ Panic Disorders
Dx: Anxiety/Panic, Depression 
______________________________________________________
"If you doubt you can accomplish something, then you can’t accomplish it. You have to have confidence in your ability, and then be tough enough to follow through.” 
~Rosalyn Carter


Licho
Regular Member


Date Joined Jun 2007
Total Posts : 98
   Posted 6/17/2007 12:58 PM (GMT -6)   
I see, I guessed that your intention was such. Never mind. yeah
 
And I hope I've not written anything obscene that you've edited my post :-)
 
Cordial cheers! :-)
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