How long does it take for Klonopin to kick in?

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New Member

Date Joined Jul 2007
Total Posts : 19
   Posted 7/22/2007 6:58 PM (GMT -6)   
I have been taking Klonopin .25mg on an as needed basis. I have noticed it take effect after 30-40 mins..
Anyone else out there taking klonopin? How long does it take for it to kick in? Any side-effects?


Veteran Member

Date Joined Nov 2006
Total Posts : 1745
   Posted 7/22/2007 7:15 PM (GMT -6)   
Your dose is really, really small so side effects should be minimal. Some drowsiness. That'll go away with time. Take a look at this website for a very comprehensive look at Klonopin side-effects:

Pay attention to the first column of Table 1. Those are from clinical trials and are accurate. The first column is for 1mg or less per day, and you probably won't be taking that much of it very often.

Klonopin "peaks" from 1-4 hours after the dose is administered. That's the official story, but it varies a great deal from person to person. For example, even when I was a little kid I always metabolized meds slowly. I don't even feel my Klonopin beginning to work until an hour and fifteen minutes or so, and that's if I took it on an empty stomach. My doctor said I should take it on an empty stomach, by the way.

Klonopin's not really designed to work on an as-needed basis. Plenty of people take it that way with good results, but they're not really taking full advantage of the medicine that way. Its slow onset just doesn't make it ideal for that kind of dosing, and it was designed to be dosed at least twice a day so that it would reach a steady plasma level. There's lots of info on Roche's website about it (it and Valium are their top sellers, I think). And they've recently developed a wafer that works a lot faster. Ask your doctor about that.

Don't mean to imply that your doctor was "wrong" to put you on the K PRN. That's a medical decision.
My Brain: My friend, My enemy: A blog to chronicle my attempt to recover from anxiety/panic disorder

Forum Moderator

Date Joined Apr 2007
Total Posts : 32602
   Posted 7/22/2007 7:51 PM (GMT -6)   


Debaser is right, Klonopin works best when there is a constant amount in the bloodstream. To keep blood levels as constant as possible, the doses should be taken at regularly spaced intervals. (source: PDR, 7th edition)

Stay with us and keep posting. yeah

Moderator Anxiety ~ Panic Disorders
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Regular Member

Date Joined Feb 2005
Total Posts : 162
   Posted 7/23/2007 11:31 AM (GMT -6)   
hi, ive been taking 1mg at night before i go to bed for about a week now...i took half a tablet once during the day b/c i felt an attack coming on, and it helped me calm down but i was pretty spacey.

other than that i did have a sore throat, light fever this week that i posted about already, i DEFINITELY think it was from the klonopin but i stuck with it and now im fine.

i hope it works well for you!
"On really romantic evenings of self, I go salsa dancing with my confusion."

Crohn's - (Asacol)
Anxiety - (Klonopin)

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