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Posted By : BrendaGN - 5/12/2016 9:29 AM
Hi I am new to this forum and have a fairly new DX of RA. I have been on Methotrexate and Humeria, but have had so many side effects from the MTX that my Dr. has dropped it completely. I am still taking the Humeria injections every two weeks. My question is does the Humeria work for any of you without MTX? I've read that they usually go together. I'm so ready for some relief.


Posted By : Don_D - 5/12/2016 12:26 PM
Hi Brenda and welcome!

I have read lots that biologics are many times prescribed with MTX but my experience over the last 20 years was that I had a very bad reaction to MTX in pill form in the beginning so my Rheumy scrapped it and put my on Enbrel. This worked great for me for many years all by itself. I also took Orencia and Humira without it but Humira did not work well for me.

about 3 years ago I had a very severe flare up and was put on MTX injection in addition to my other meds and it has helped some. Not enough to really control my disease well but it has helped keep me from those severe flares which is a plus.

I hope that you find relief soon. Sometimes these meds can take a while to truly work and can be quite gradual. Other times they can be quite effective very quickly. I hope for you that it is soon :)

Take care.

Posted By : BrendaGN - 5/12/2016 1:27 PM
Thanks Don, I'm really happy to find a place that I can discuss RA. Sometimes I feel like my Dr talks completely over my head.

Posted By : Don_D - 5/13/2016 11:05 AM
Trust me, we all know where you are coming from. This is a great place to post your questions because there always seems to be someone here who has had the same experience at some point.


Posted By : celebrate life - 5/14/2016 12:01 PM
Hi Brenda and welcome to the HW forum!
I hope we can be of some support and comfort to you.
My first biologic was humira and I was able to get back to an almost normal lifestyle on just humira alone. It quit working well after about five years. Now I'm on Enbril with mtx. I just can't get the same relief without having the mtx added in. Even though I still don't feel as good as I would like, my last blood panel came back all normal, even the sedrate.
How long ago were you put on Humira? It gave me relief really fast. I hope the same is true for you!
P.s. It's good to see you posting again Don. I hope you are having better days with diminishing side effects.

Posted By : Don_D - 5/15/2016 2:32 AM
Hi Beth! Thanks :) The side effects are far better now. I have no biologics left to take though at this point so I am living on MTX and my Rheumy wants me back on Prednizone again :(

Unfortunately all my test results are back to high disease activity levels and Im struggling but it is what it is. It is better than the alternative right? :)

Sorry for the thread hijack Brenda. I hope you are feeling better.

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