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Posted By : Jd7 - 3/2/2017 3:47 PM
I've been on humira for 14 years. Just recently I had to stop it for a month due to illness. Now that I've resumed humira, it no longer works. It's very upsetting bc I've been doing so great on it. My dr is switching my biologic to enbrel instead. He said that I have a 33% chance of it working. I'm wondering if this had happened to anyone else, and if switching to a new biologic worked.

Posted By : BadDay - 3/2/2017 7:01 PM
Hi I posted a response to your other post but just a Quick not to this one the answer is Yes Every Biologic works that little bit different so by switching you may get a better result Just Keep Good contact with your Doctor Talk Everything over with Him and Ask Questions
FORUM MODERATOR Rheumatoid Arthritis for 30Yrs. Asthma,Fibromyalgia,Osteoperosis,Cervical Spondalosos,Degenerative Disc Disese,Disc Bulges, Diabetes,Heart SVT & AF, Sleep apnoea,Nocturnal Respiratory Failure,Panic Attacks,Anxiety
on; Methotrexate , Arava , Endone, Targin 20mg (oxycontin) , Prednisone, Metforman(Diabex) , Tambocor. Oxygen & Cpap, Prolia Injection ,Lyrica

Posted By : Jd7 - 3/2/2017 7:48 PM
Thank you for taking the time to answer my questions. I really appreciate it. Also, thanks for giving me hope. I will stay positive, and hope for the best. I don't start my new biologic until late next week. I'll keep my fingers crossed! 🙂

Posted By : celebrate life - 3/3/2017 12:50 AM
JD 7,
Welcome to the HW forum. There are a lot of good people here with similar experiences. I had exactly the same thing happen to me. I was on humira for 10 years with fabulous results. The enbril has been pretty darn good at keeping my RA in check, but not quite as good, so I have added methotrexate and continue prednisone at as low a dose as I can manage.
The last two weeks have been not so good for me with constant foot flares. But most of the time I can work and exercise with little or no pain from RA.
How have you been doing with joint pain? Are you taking any other meds? There are several new meds out now that might work if enbril fails. Give it several weeks, though.
Best wishes.

Posted By : Jd7 - 3/3/2017 8:54 AM
Thank you Beth. Right now I'm on Celebrex 2x a day and prednisone 5-10mg a day. I'm still on the humira, but it only works for about 5-6 days, and doesn't give me full relief like it did before. My joint pain has come back like crazy. I haven't had a flare like this in 15 years or more. I've had JRA since I was 15. I'm now 50. Unfortunately when I was diagnosed, they really didn't have to much to help with the joint damage, mostly just pain relievers. What little they had (gold, plaquenille) didn't work for me. I've had double hip replacements. I've been doing great though, and consider myself lucky 🍀. I know that I could be way worse. I never took it for granted how great I felt on humira. I was thankful every day. So it's really depressing that it stopped working and that I am back to having trouble getting moving in the mornings. My ankles and feet are really bothering me. I had to stop my humira twice this winter due to illness. Once I restarted, it just doesn't work. I've taken 3-4 injections with no improvement. Through research, and speaking with my doctor, I've found out that your bday can develop antibodies to the medicine, which make it useless. I know that my doctor feels bad that he had me stop the medicine, but he was just doing what he thought was best for me. Hopefully the enbrel will work.

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